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The map label for this gene is argS

Identifier: 32266208

GI number: 32266208

Start: 687966

End: 689612

Strand: Direct

Name: argS

Synonym: HH0709

Alternate gene names: 32266208

Gene position: 687966-689612 (Clockwise)

Preceding gene: 32266207

Following gene: 32266209

Centisome position: 38.24

GC content: 35.34

Gene sequence:

>1647_bases
ATGCACCACCATATCAAAGCTCTTCTCCAAAGTGCATTGAATATTAAAAACACAATTGACATTGTGCTTGAGAGACCAAA
AAACAAAGACTTGGGGCATTTTGCTACACCTCTTGCCCTTAGCCTTGCTAAGATTGAAAAAACCAATCCTAAGCTTATCG
CTGAAGAGATTGCTAAAATACTTACAAATTACGCAGAGTTTGAAAAAGTAGAAACTCTCAATGGCTTTGTAAATCTCACA
CTTTCTACAACTTTTCTTCAACATATTGCACAAAAACAACTGCAGCATTGTATGACTCTTGAAGCAGATTCTATAAATCC
TAACATATCTCAATATACACAAAAGACTCAAATAACACCAAAAGAGCATATTTTGATTGAATTTGTCAGTGCCAATCCCA
CAGGACCGCTTCACATTGGGCACGCAAGAGGTGCTGTATATGGCGATGCACTTACTCGTGTAGGGCGGTTTTTAGGTTAT
GATATACTCACCGAATATTATATAAACGATGCAGGGGCACAGATTTATATGCTTGGGCTATCAATTTTTCTTGCAGGGAG
AGAACATATCCTTAAAACTCAAGTAGAATATCCACAAAGTTATTATAAGGGCGAATATATTATTGATTTAGCAAAACAAT
GTGCGCTACACTTTGGTGAAGATGTTTTTAAAAGTGAAGATTCTATCTCCTCTCTTGCAGATTTTGGCAAAGATATGATG
CTTCAAGAGATTAAAGATAATCTAGCGCAAGTTGGGATTAAATTTGATTCCTTTGTGAGCGAAAAATCCCTTTATGACAG
ATGGCAAGATACGCTTGATACTTTAAAATCTCATCAAGGTATTTATACCAAAGATGGCAAAATCTGGATTGCTTCCTCGC
AAATCAATGATGAAAAAGACCGAGTTGTCGTGAGGGAGAATGGTGAGCCGACCTATCTTGCTGGAGATATTATCTATCAT
CAAGATAAATTTCATCGCCATTTTGAACATTATATTAATATTTGGGGAGCCGATCATCACGGCTATATTGCACGCGTAAA
GGCAGCTATTCATTTTTTGGGCTATGATGAAAATAAACTTGAAGTGTTGCTTTCTCAAATGGTAAGCCTTCTTAAAGGTG
GGCAACCTTATAAAATGAGTAAACGTGCAGGAAATTTTATCCTTATGAAAGATGTAATAGAAGATATTGGAGCTGATGCA
CTTCGTTTTATTTTTCTCTCTAAAAAACCTGATACACACCTTGAATTTGATGTTGATGAACTTAAAAAAGAAGATGGAAG
CAATCCTATTTATTATATTAACTATGCTAATGCTAGAATCCACACACTTTTTAATAAAGCTGGAGTAAATATGCAGCAGA
CAGCACAAAATGCGAATAAATTGGATATAAATGAACAAGCAAAGGCGCTTTTGTTTGAAGCTCTTTGTCTGCAACAAATA
ATAGAATCTAGCTTTCGCAATAGAGAGATTCAAAAAATATGTGATTATCTTAAAAGCCTCTCTGCTTCATTTCACAGCTT
TTATAATACACACAAAATCTTGCAAAGTCCAAATGAATCAAGTATTCTTTATGTGCTAATGATTGTCAGCCAAAGCCTCA
CACTTGGATTATCTCTGCTTGGAATTAAAGCAAAAACAAGAATGTAA

Upstream 100 bases:

>100_bases
ATCAAAGTGAAGAAAATACAAAATCTCAAATCAAACAAAGCGAATCTAAAAATGAGAATGTATCAAAAACTCACACAGAT
TCTCAAAAACAAGACACTTA

Downstream 100 bases:

>100_bases
TATGTGCCAGAGCTCAAAAGCATTTATTGCACTTAAAGATGCTTTTCCACATACAATTCCTATTATGCTTGGTTATATTT
TTATGGGTGCAGTATTTGGT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MHHHIKALLQSALNIKNTIDIVLERPKNKDLGHFATPLALSLAKIEKTNPKLIAEEIAKILTNYAEFEKVETLNGFVNLT
LSTTFLQHIAQKQLQHCMTLEADSINPNISQYTQKTQITPKEHILIEFVSANPTGPLHIGHARGAVYGDALTRVGRFLGY
DILTEYYINDAGAQIYMLGLSIFLAGREHILKTQVEYPQSYYKGEYIIDLAKQCALHFGEDVFKSEDSISSLADFGKDMM
LQEIKDNLAQVGIKFDSFVSEKSLYDRWQDTLDTLKSHQGIYTKDGKIWIASSQINDEKDRVVVRENGEPTYLAGDIIYH
QDKFHRHFEHYINIWGADHHGYIARVKAAIHFLGYDENKLEVLLSQMVSLLKGGQPYKMSKRAGNFILMKDVIEDIGADA
LRFIFLSKKPDTHLEFDVDELKKEDGSNPIYYINYANARIHTLFNKAGVNMQQTAQNANKLDINEQAKALLFEALCLQQI
IESSFRNREIQKICDYLKSLSASFHSFYNTHKILQSPNESSILYVLMIVSQSLTLGLSLLGIKAKTRM

Sequences:

>Translated_548_residues
MHHHIKALLQSALNIKNTIDIVLERPKNKDLGHFATPLALSLAKIEKTNPKLIAEEIAKILTNYAEFEKVETLNGFVNLT
LSTTFLQHIAQKQLQHCMTLEADSINPNISQYTQKTQITPKEHILIEFVSANPTGPLHIGHARGAVYGDALTRVGRFLGY
DILTEYYINDAGAQIYMLGLSIFLAGREHILKTQVEYPQSYYKGEYIIDLAKQCALHFGEDVFKSEDSISSLADFGKDMM
LQEIKDNLAQVGIKFDSFVSEKSLYDRWQDTLDTLKSHQGIYTKDGKIWIASSQINDEKDRVVVRENGEPTYLAGDIIYH
QDKFHRHFEHYINIWGADHHGYIARVKAAIHFLGYDENKLEVLLSQMVSLLKGGQPYKMSKRAGNFILMKDVIEDIGADA
LRFIFLSKKPDTHLEFDVDELKKEDGSNPIYYINYANARIHTLFNKAGVNMQQTAQNANKLDINEQAKALLFEALCLQQI
IESSFRNREIQKICDYLKSLSASFHSFYNTHKILQSPNESSILYVLMIVSQSLTLGLSLLGIKAKTRM
>Mature_548_residues
MHHHIKALLQSALNIKNTIDIVLERPKNKDLGHFATPLALSLAKIEKTNPKLIAEEIAKILTNYAEFEKVETLNGFVNLT
LSTTFLQHIAQKQLQHCMTLEADSINPNISQYTQKTQITPKEHILIEFVSANPTGPLHIGHARGAVYGDALTRVGRFLGY
DILTEYYINDAGAQIYMLGLSIFLAGREHILKTQVEYPQSYYKGEYIIDLAKQCALHFGEDVFKSEDSISSLADFGKDMM
LQEIKDNLAQVGIKFDSFVSEKSLYDRWQDTLDTLKSHQGIYTKDGKIWIASSQINDEKDRVVVRENGEPTYLAGDIIYH
QDKFHRHFEHYINIWGADHHGYIARVKAAIHFLGYDENKLEVLLSQMVSLLKGGQPYKMSKRAGNFILMKDVIEDIGADA
LRFIFLSKKPDTHLEFDVDELKKEDGSNPIYYINYANARIHTLFNKAGVNMQQTAQNANKLDINEQAKALLFEALCLQQI
IESSFRNREIQKICDYLKSLSASFHSFYNTHKILQSPNESSILYVLMIVSQSLTLGLSLLGIKAKTRM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=566, Percent_Identity=21.5547703180212, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI197100773, Length=482, Percent_Identity=21.7842323651452, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1788184, Length=564, Percent_Identity=22.3404255319149, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71985061, Length=607, Percent_Identity=21.5815485996705, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985068, Length=568, Percent_Identity=22.0070422535211, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320548, Length=554, Percent_Identity=19.6750902527076, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321883, Length=567, Percent_Identity=21.5167548500882, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571570, Length=480, Percent_Identity=22.2916666666667, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_HELHP (Q7VI99)

Other databases:

- EMBL:   AE017125
- RefSeq:   NP_860240.1
- ProteinModelPortal:   Q7VI99
- GeneID:   1493763
- GenomeReviews:   AE017125_GR
- KEGG:   hhe:HH0709
- NMPDR:   fig|235279.1.peg.709
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   HHEP235279:HH_0709-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 62313; Mature: 62313

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHHIKALLQSALNIKNTIDIVLERPKNKDLGHFATPLALSLAKIEKTNPKLIAEEIAKI
CCHHHHHHHHHHHCCCCCEEHEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LTNYAEFEKVETLNGFVNLTLSTTFLQHIAQKQLQHCMTLEADSINPNISQYTQKTQITP
HHHHHHHHHHHHHCHHEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCC
KEHILIEFVSANPTGPLHIGHARGAVYGDALTRVGRFLGYDILTEYYINDAGAQIYMLGL
CCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
SIFLAGREHILKTQVEYPQSYYKGEYIIDLAKQCALHFGEDVFKSEDSISSLADFGKDMM
HHHHHCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHH
LQEIKDNLAQVGIKFDSFVSEKSLYDRWQDTLDTLKSHQGIYTKDGKIWIASSQINDEKD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCCCC
RVVVRENGEPTYLAGDIIYHQDKFHRHFEHYINIWGADHHGYIARVKAAIHFLGYDENKL
EEEEEECCCCCEEECCEEECHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCHHH
EVLLSQMVSLLKGGQPYKMSKRAGNFILMKDVIEDIGADALRFIFLSKKPDTHLEFDVDE
HHHHHHHHHHHCCCCCCCHHHCCCCEEEHHHHHHHHCCHHEEHEEECCCCCCCEECCHHH
LKKEDGSNPIYYINYANARIHTLFNKAGVNMQQTAQNANKLDINEQAKALLFEALCLQQI
HHHCCCCCCEEEEEECCCEEEEHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
IESSFRNREIQKICDYLKSLSASFHSFYNTHKILQSPNESSILYVLMIVSQSLTLGLSLL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHE
GIKAKTRM
ECCHHCCC
>Mature Secondary Structure
MHHHIKALLQSALNIKNTIDIVLERPKNKDLGHFATPLALSLAKIEKTNPKLIAEEIAKI
CCHHHHHHHHHHHCCCCCEEHEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LTNYAEFEKVETLNGFVNLTLSTTFLQHIAQKQLQHCMTLEADSINPNISQYTQKTQITP
HHHHHHHHHHHHHCHHEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCC
KEHILIEFVSANPTGPLHIGHARGAVYGDALTRVGRFLGYDILTEYYINDAGAQIYMLGL
CCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
SIFLAGREHILKTQVEYPQSYYKGEYIIDLAKQCALHFGEDVFKSEDSISSLADFGKDMM
HHHHHCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHH
LQEIKDNLAQVGIKFDSFVSEKSLYDRWQDTLDTLKSHQGIYTKDGKIWIASSQINDEKD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCCCC
RVVVRENGEPTYLAGDIIYHQDKFHRHFEHYINIWGADHHGYIARVKAAIHFLGYDENKL
EEEEEECCCCCEEECCEEECHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCHHH
EVLLSQMVSLLKGGQPYKMSKRAGNFILMKDVIEDIGADALRFIFLSKKPDTHLEFDVDE
HHHHHHHHHHHCCCCCCCHHHCCCCEEEHHHHHHHHCCHHEEHEEECCCCCCCEECCHHH
LKKEDGSNPIYYINYANARIHTLFNKAGVNMQQTAQNANKLDINEQAKALLFEALCLQQI
HHHCCCCCCEEEEEECCCEEEEHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
IESSFRNREIQKICDYLKSLSASFHSFYNTHKILQSPNESSILYVLMIVSQSLTLGLSLL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHE
GIKAKTRM
ECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12810954