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The map label for this gene is xanB [H]

Identifier: 32266174

GI number: 32266174

Start: 655154

End: 656587

Strand: Direct

Name: xanB [H]

Synonym: HH0675

Alternate gene names: 32266174

Gene position: 655154-656587 (Clockwise)

Preceding gene: 32266172

Following gene: 32266175

Centisome position: 36.41

GC content: 36.19

Gene sequence:

>1434_bases
ATGACGATTTCAATCCTTTGTGGTGGCTCTGGCACGCGTCTTTTCCCCCTATCGCGTGAGCTTTTGCCTAAACAATTTGC
TAATCTACTTCCATCTAAAAACGCTCAAACTTCCTCACACTCACTTTTCCAAGAGACACTTTTGCGCAATGATTTTTTAC
GCAAAAGCCACAAGGGCAAATTCCAAATTATTACCAATGATAATCACTACTTCATCGCGCAAGAACAAGCTCACAAAATT
AATATTCCCTTATCAGAATTTATTTTAGAATCTCTTGGCAAAAACACCGCTCCAGCACTTACTTTTGCGGCTCTAAAGTC
TTTAGAATCTTTTTCACTCAATCAAAATGAAGATGATATTATTCTTGCGCTGCCAAGCGACCACCTTATCAAAAATACTG
CTGATTACGAACAGAGTATATTTCAAGCCATAGAATTAGCACAAAAAGGATTCTTAGTTACTTTTGGGATTAAGCCAAAT
TGCCCACATACAGGCTATGGCTATATTAAGGCAAAAGATAGCGTTGTAGAAAAATTCATTGAAAAGCCCTCCATTAAAGA
TGCTAAAGCTTATGTAGAAAATGGCAACTATCTATGGAATAGCGGTATGTTTTGCTTTAAAGCAGAAGTGTTTTTACAAG
AGCTTGAAGTGCATAACCCAGAAGTATATAAGCGCTGTAAGCTTACTTTTGAAGCTTCTAAGGAAAGTGAAGCAAAGGAT
TTTATCCGCTTAGATGCCAAAATGAGTGAAAATTTGCCTGATATTAGCATAGATTACGCATTAATGGAAAAAAGTCAAAA
GGTCGCTTGTGTGAGTAGCAATTTTATATGGAATGATATTGGAAGTTTTGAATCTCTCTCTAATGAATATCCCACAGATG
AAGCAGAAAATGCAAGTAAAAATACCTTTATTCAAAAAGAATGCAAAAATAATTTTGTCATTTCAGATAAGCTTGTCGCA
GGGATTGGGCTAGAGGATTTAATGATTATTGATGAAAACGATTGCCTCTTAATAGCCAAAAAAGGGTATTCTCAACAAGT
CAAAGATATTGTGGCTTTGCTAAAAACTACCCACCCTGAACTTACTCAAATTCACAAAACTGCTCATCGCCCTTGGGGAA
CTTATACAATTTTATTAGAATCTCAAAATTACAAAATCAAGCAAATTGTCGTTAAGCCAAAGGGCAAATTGAGCTTACAA
AAACATTATCATCGTAATGAACATTGGATTATTGTAAGCGGTTGTGCCATAATTACACTTGGAGAATCACAAAAATTCCT
CAAAGCAAATCAAAGCACTTATATTCCTATGGGTGAGGTGCATAGACTTGAAAATCCCGGAATCCTGCCACTTGTACTCA
TTGAAGTGCAAATGGGAGAATATTTAGGTGAAGATGACATCGTGCGTTTGAGCGATGATTATCAGCGTAAATAA

Upstream 100 bases:

>100_bases
GTGCAAAGGAGATTCTTAAAAAAGAGGCAAATATTCTCATTGAGACGCAAGATTTAAGAGAAATTCCTAAAGCTCTCAAT
ATTCCCTTTAAGGAGTAAAT

Downstream 100 bases:

>100_bases
TGATTATAGCCATAGTCGTAGATAGTTATAAAGATAGAAGTAATGGCACTTCTATGACAGCCTTTCGCTTTGCAAGAGCT
TTGATCGAAAGAGGACACTG

Product: hypothetical protein

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MTISILCGGSGTRLFPLSRELLPKQFANLLPSKNAQTSSHSLFQETLLRNDFLRKSHKGKFQIITNDNHYFIAQEQAHKI
NIPLSEFILESLGKNTAPALTFAALKSLESFSLNQNEDDIILALPSDHLIKNTADYEQSIFQAIELAQKGFLVTFGIKPN
CPHTGYGYIKAKDSVVEKFIEKPSIKDAKAYVENGNYLWNSGMFCFKAEVFLQELEVHNPEVYKRCKLTFEASKESEAKD
FIRLDAKMSENLPDISIDYALMEKSQKVACVSSNFIWNDIGSFESLSNEYPTDEAENASKNTFIQKECKNNFVISDKLVA
GIGLEDLMIIDENDCLLIAKKGYSQQVKDIVALLKTTHPELTQIHKTAHRPWGTYTILLESQNYKIKQIVVKPKGKLSLQ
KHYHRNEHWIIVSGCAIITLGESQKFLKANQSTYIPMGEVHRLENPGILPLVLIEVQMGEYLGEDDIVRLSDDYQRK

Sequences:

>Translated_477_residues
MTISILCGGSGTRLFPLSRELLPKQFANLLPSKNAQTSSHSLFQETLLRNDFLRKSHKGKFQIITNDNHYFIAQEQAHKI
NIPLSEFILESLGKNTAPALTFAALKSLESFSLNQNEDDIILALPSDHLIKNTADYEQSIFQAIELAQKGFLVTFGIKPN
CPHTGYGYIKAKDSVVEKFIEKPSIKDAKAYVENGNYLWNSGMFCFKAEVFLQELEVHNPEVYKRCKLTFEASKESEAKD
FIRLDAKMSENLPDISIDYALMEKSQKVACVSSNFIWNDIGSFESLSNEYPTDEAENASKNTFIQKECKNNFVISDKLVA
GIGLEDLMIIDENDCLLIAKKGYSQQVKDIVALLKTTHPELTQIHKTAHRPWGTYTILLESQNYKIKQIVVKPKGKLSLQ
KHYHRNEHWIIVSGCAIITLGESQKFLKANQSTYIPMGEVHRLENPGILPLVLIEVQMGEYLGEDDIVRLSDDYQRK
>Mature_476_residues
TISILCGGSGTRLFPLSRELLPKQFANLLPSKNAQTSSHSLFQETLLRNDFLRKSHKGKFQIITNDNHYFIAQEQAHKIN
IPLSEFILESLGKNTAPALTFAALKSLESFSLNQNEDDIILALPSDHLIKNTADYEQSIFQAIELAQKGFLVTFGIKPNC
PHTGYGYIKAKDSVVEKFIEKPSIKDAKAYVENGNYLWNSGMFCFKAEVFLQELEVHNPEVYKRCKLTFEASKESEAKDF
IRLDAKMSENLPDISIDYALMEKSQKVACVSSNFIWNDIGSFESLSNEYPTDEAENASKNTFIQKECKNNFVISDKLVAG
IGLEDLMIIDENDCLLIAKKGYSQQVKDIVALLKTTHPELTQIHKTAHRPWGTYTILLESQNYKIKQIVVKPKGKLSLQK
HYHRNEHWIIVSGCAIITLGESQKFLKANQSTYIPMGEVHRLENPGILPLVLIEVQMGEYLGEDDIVRLSDDYQRK

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=483, Percent_Identity=37.6811594202899, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 54078; Mature: 53947

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISILCGGSGTRLFPLSRELLPKQFANLLPSKNAQTSSHSLFQETLLRNDFLRKSHKGK
CEEEEEECCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
FQIITNDNHYFIAQEQAHKINIPLSEFILESLGKNTAPALTFAALKSLESFSLNQNEDDI
EEEEECCCEEEEEECCCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCE
ILALPSDHLIKNTADYEQSIFQAIELAQKGFLVTFGIKPNCPHTGYGYIKAKDSVVEKFI
EEECCCCHHHCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECHHHHHHHH
EKPSIKDAKAYVENGNYLWNSGMFCFKAEVFLQELEVHNPEVYKRCKLTFEASKESEAKD
HCCCCCCHHHHHCCCCEEECCCCEEEHHHHHHHHHHCCCHHHHHHEEEEEECCCCCHHHH
FIRLDAKMSENLPDISIDYALMEKSQKVACVSSNFIWNDIGSFESLSNEYPTDEAENASK
HHEECCHHHCCCCCCEEEHHHHCCCCCEEEEECCCEECCCCCHHHHCCCCCCCCCCCCCC
NTFIQKECKNNFVISDKLVAGIGLEDLMIIDENDCLLIAKKGYSQQVKDIVALLKTTHPE
CCEEHHHHCCCCEEECHHHCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCCHH
LTQIHKTAHRPWGTYTILLESQNYKIKQIVVKPKGKLSLQKHYHRNEHWIIVSGCAIITL
HHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCEEHHHHHCCCCCEEEEECEEEEEE
GESQKFLKANQSTYIPMGEVHRLENPGILPLVLIEVQMGEYLGEDDIVRLSDDYQRK
CCCCHHHHCCCCCCCCCHHHHCCCCCCCEEEEEEEEEHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TISILCGGSGTRLFPLSRELLPKQFANLLPSKNAQTSSHSLFQETLLRNDFLRKSHKGK
EEEEEECCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
FQIITNDNHYFIAQEQAHKINIPLSEFILESLGKNTAPALTFAALKSLESFSLNQNEDDI
EEEEECCCEEEEEECCCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCE
ILALPSDHLIKNTADYEQSIFQAIELAQKGFLVTFGIKPNCPHTGYGYIKAKDSVVEKFI
EEECCCCHHHCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEECHHHHHHHH
EKPSIKDAKAYVENGNYLWNSGMFCFKAEVFLQELEVHNPEVYKRCKLTFEASKESEAKD
HCCCCCCHHHHHCCCCEEECCCCEEEHHHHHHHHHHCCCHHHHHHEEEEEECCCCCHHHH
FIRLDAKMSENLPDISIDYALMEKSQKVACVSSNFIWNDIGSFESLSNEYPTDEAENASK
HHEECCHHHCCCCCCEEEHHHHCCCCCEEEEECCCEECCCCCHHHHCCCCCCCCCCCCCC
NTFIQKECKNNFVISDKLVAGIGLEDLMIIDENDCLLIAKKGYSQQVKDIVALLKTTHPE
CCEEHHHHCCCCEEECHHHCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCCHH
LTQIHKTAHRPWGTYTILLESQNYKIKQIVVKPKGKLSLQKHYHRNEHWIIVSGCAIITL
HHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCEEHHHHHCCCCCEEEEECEEEEEE
GESQKFLKANQSTYIPMGEVHRLENPGILPLVLIEVQMGEYLGEDDIVRLSDDYQRK
CCCCHHHHCCCCCCCCCHHHHCCCCCCCEEEEEEEEEHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]