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The map label for this gene is slyD

Identifier: 32265936

GI number: 32265936

Start: 418996

End: 419550

Strand: Direct

Name: slyD

Synonym: HH0437

Alternate gene names: 32265936

Gene position: 418996-419550 (Clockwise)

Preceding gene: 32265935

Following gene: 32265937

Centisome position: 23.29

GC content: 44.5

Gene sequence:

>555_bases
ATGATTGCACAAAATAAAATCGTTAGTATTGAATACGAAGTCTTTAATCAAGCTGACAATACGCTACTTGATTCAAACAA
AAATGGTGCGCCACTTGAATTTCTTGTCGGTTCAGGACAAGTCATTAGCGGGCTTGAGAATGCCCTTATGGGGGCAAGTA
TAGGTGACAATGTCAAAGCTACTATTGCACCTGAAGATGCTTATGGAACTTATCAAAGCGACTTTGTGCAGGAAGTAGCA
CGAGAGCAATTTGAGGGCATTGAGCTTAAAGCAGGTATGACACTTTTTGGACAAGGGGAAGATGGGCAAACTGTGCAAGT
GAGTGTCAAAGATTTCAATGATAAATTTGTTATCATTGATTATAATCACCCTCTTGCAGGCAAAACACTTAATTTTGATG
TGAAAATCATCGATGTGCGCGAAGCAACAGAAATGGAAATTTTGCAAGGTGGTGTTGGTGGGGGCTGTGGCTGCAGTAGT
GGTGGCGGACATAGCGGTGGAGGTTGCTGCGGTGGTGGCGGACATAGCGGTGGGGGCTGTGGCTGCAGCCACTAG

Upstream 100 bases:

>100_bases
AAAACTATAATAAGTTTTTGGATTCTTTGATAGGCAATTATCCCTCAAGTAAAGAAGCTCAAAGTGCCAAAAAACTTAAA
ACTCAAAATAAGGAAAAAAA

Downstream 100 bases:

>100_bases
GTCTTAAGGCAATAAAATCCTAGAATCTAAATGTAAGTTTAGATTCTCTGCAAGGAGAGCAAACGTCTCTGGTGGGCGTC
TTGGGCTTCAAACCCATTGA

Product: FKBP-type peptidyl-prolyl cis-trans isomerase 2

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIAQNKIVSIEYEVFNQADNTLLDSNKNGAPLEFLVGSGQVISGLENALMGASIGDNVKATIAPEDAYGTYQSDFVQEVA
REQFEGIELKAGMTLFGQGEDGQTVQVSVKDFNDKFVIIDYNHPLAGKTLNFDVKIIDVREATEMEILQGGVGGGCGCSS
GGGHSGGGCCGGGGHSGGGCGCSH

Sequences:

>Translated_184_residues
MIAQNKIVSIEYEVFNQADNTLLDSNKNGAPLEFLVGSGQVISGLENALMGASIGDNVKATIAPEDAYGTYQSDFVQEVA
REQFEGIELKAGMTLFGQGEDGQTVQVSVKDFNDKFVIIDYNHPLAGKTLNFDVKIIDVREATEMEILQGGVGGGCGCSS
GGGHSGGGCCGGGGHSGGGCGCSH
>Mature_184_residues
MIAQNKIVSIEYEVFNQADNTLLDSNKNGAPLEFLVGSGQVISGLENALMGASIGDNVKATIAPEDAYGTYQSDFVQEVA
REQFEGIELKAGMTLFGQGEDGQTVQVSVKDFNDKFVIIDYNHPLAGKTLNFDVKIIDVREATEMEILQGGVGGGCGCSS
GGGHSGGGCCGGGGHSGGGCGCSH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=39.4557823129252, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI1786211, Length=121, Percent_Identity=29.7520661157025, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19015; Mature: 19015

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAQNKIVSIEYEVFNQADNTLLDSNKNGAPLEFLVGSGQVISGLENALMGASIGDNVKA
CCCCCEEEEEEEHEECCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEE
TIAPEDAYGTYQSDFVQEVAREQFEGIELKAGMTLFGQGEDGQTVQVSVKDFNDKFVIID
EECCCCCCCCHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCCEEEEEEEECCCEEEEEE
YNHPLAGKTLNFDVKIIDVREATEMEILQGGVGGGCGCSSGGGHSGGGCCGGGGHSGGGC
CCCCCCCCEEEEEEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GCSH
CCCC
>Mature Secondary Structure
MIAQNKIVSIEYEVFNQADNTLLDSNKNGAPLEFLVGSGQVISGLENALMGASIGDNVKA
CCCCCEEEEEEEHEECCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEE
TIAPEDAYGTYQSDFVQEVAREQFEGIELKAGMTLFGQGEDGQTVQVSVKDFNDKFVIID
EECCCCCCCCHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCCEEEEEEEECCCEEEEEE
YNHPLAGKTLNFDVKIIDVREATEMEILQGGVGGGCGCSSGGGHSGGGCCGGGGHSGGGC
CCCCCCCCEEEEEEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GCSH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]