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The map label for this gene is aatC [H]

Identifier: 32265871

GI number: 32265871

Start: 363192

End: 364349

Strand: Direct

Name: aatC [H]

Synonym: HH0372

Alternate gene names: 32265871

Gene position: 363192-364349 (Clockwise)

Preceding gene: 32265870

Following gene: 32265872

Centisome position: 20.19

GC content: 39.12

Gene sequence:

>1158_bases
TTGCTACATCAATTTGAAAGCTATCCTTTTGAAAAACTCCGCACTCTACTTGCTCATAGCTCTCCTCCGAGCGGTGAAGA
GATTTTTTCACTCACTATCGGCGAACCCCAATTTCCTACACCTACTAATATTATACAATCGTGGCAAAGCAATGCCTCTT
TGCTCAATAAATACCCAAAATCAAGCGGTGAAGACGAGCTTAAAGACGCACAGCTTCACTTCATAAACAAACGTTACAAT
CTCACGCTTACAAAAAGCCAAATTATTCCTACTCTTGGCACACGCGAAGTGCTTTTTAATTTTCCGCAATTTTATCTTTT
TGACTTGCCACAGCCTACTATTGCCTATCCTAATCCTTTTTATCAAATCTATGAGGGTGCGGCTATTGCCTCAAAAGCGC
AGGTTTTACTAATGAATCTTACAAGCGAAAATGACTTCACTCCCTCACTCACGCCCAAAGAGCTAAAAAAAGTCCATTTA
GTTATTCTTAATTCTCCTAATAACCCCACAGGTAGAATACTAGATATGCAAGCACTTACAGAATGGGTGAAAAAAGCACT
TGAATATGATTTTGTGATTATAAATGATGAATGTTATAGTGAAATTTATGAGTCTTCCCCTCCACCAAGCATTCTCCAAG
CTTCAATTCAAGCAGGTAATACAAGTTTTAAAAATATCATTGCTCTCAATTCTATTTCCAAACGCTCCTCCGCTCCGGGT
TTGCGTAGCGGTTTTATCGCCGGAGATGCTGAAATTTTAAAAGCCTACAACCTCTATCGCACTTATTTGGGCTGTGCACT
GCCATTACCTTTGCAAAAAGCTGCTGCCGTAGCGTGGAAAGATATGCAAACTCCTGAATCTATCCGACACATTTATGCTA
AAAATCTCGCCTTAGCGAGGGAGATTTTAGAACTAAGCACAGAGCAAATTAGCCCTTATACCTTTTATGTATGGCTTAAA
GTTGATAATGATGAGGCATTTTGCAAATTCGCCTATGAGAAAAAAGGAGTGCTTACTCTGCCGGGTAGTTATTTAGGCAG
GGAGAATCAAGGTAAAGGCTATGTAAGAATCGCTCTTGTGTATGATAATAATACAACAAAAAAAGCACTTCTTGCCCTTA
AAGAAGCAATCAAACTTTATAAACAGGAGTGTCAATGA

Upstream 100 bases:

>100_bases
CACATATTTTAAATGGCAACTCGCCTTATTTATAATCAAGCAGATTCTCTAAATAATGCTTTCATTATATAAAGAATCTT
TAACAATGTAAGGAGCTATT

Downstream 100 bases:

>100_bases
AAATACATTTCATAGGTATTGGTGGCATTGGTATTTCAGGCTTAGCAAAATACCTCCGCGCACAAGGCATAGAAGTGAGT
GGGTCTGATATTGCAGAGGG

Product: hypothetical protein

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MLHQFESYPFEKLRTLLAHSSPPSGEEIFSLTIGEPQFPTPTNIIQSWQSNASLLNKYPKSSGEDELKDAQLHFINKRYN
LTLTKSQIIPTLGTREVLFNFPQFYLFDLPQPTIAYPNPFYQIYEGAAIASKAQVLLMNLTSENDFTPSLTPKELKKVHL
VILNSPNNPTGRILDMQALTEWVKKALEYDFVIINDECYSEIYESSPPPSILQASIQAGNTSFKNIIALNSISKRSSAPG
LRSGFIAGDAEILKAYNLYRTYLGCALPLPLQKAAAVAWKDMQTPESIRHIYAKNLALAREILELSTEQISPYTFYVWLK
VDNDEAFCKFAYEKKGVLTLPGSYLGRENQGKGYVRIALVYDNNTTKKALLALKEAIKLYKQECQ

Sequences:

>Translated_385_residues
MLHQFESYPFEKLRTLLAHSSPPSGEEIFSLTIGEPQFPTPTNIIQSWQSNASLLNKYPKSSGEDELKDAQLHFINKRYN
LTLTKSQIIPTLGTREVLFNFPQFYLFDLPQPTIAYPNPFYQIYEGAAIASKAQVLLMNLTSENDFTPSLTPKELKKVHL
VILNSPNNPTGRILDMQALTEWVKKALEYDFVIINDECYSEIYESSPPPSILQASIQAGNTSFKNIIALNSISKRSSAPG
LRSGFIAGDAEILKAYNLYRTYLGCALPLPLQKAAAVAWKDMQTPESIRHIYAKNLALAREILELSTEQISPYTFYVWLK
VDNDEAFCKFAYEKKGVLTLPGSYLGRENQGKGYVRIALVYDNNTTKKALLALKEAIKLYKQECQ
>Mature_385_residues
MLHQFESYPFEKLRTLLAHSSPPSGEEIFSLTIGEPQFPTPTNIIQSWQSNASLLNKYPKSSGEDELKDAQLHFINKRYN
LTLTKSQIIPTLGTREVLFNFPQFYLFDLPQPTIAYPNPFYQIYEGAAIASKAQVLLMNLTSENDFTPSLTPKELKKVHL
VILNSPNNPTGRILDMQALTEWVKKALEYDFVIINDECYSEIYESSPPPSILQASIQAGNTSFKNIIALNSISKRSSAPG
LRSGFIAGDAEILKAYNLYRTYLGCALPLPLQKAAAVAWKDMQTPESIRHIYAKNLALAREILELSTEQISPYTFYVWLK
VDNDEAFCKFAYEKKGVLTLPGSYLGRENQGKGYVRIALVYDNNTTKKALLALKEAIKLYKQECQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=295, Percent_Identity=26.1016949152542, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI56713254, Length=295, Percent_Identity=26.1016949152542, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788722, Length=376, Percent_Identity=26.063829787234, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 43459; Mature: 43459

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHQFESYPFEKLRTLLAHSSPPSGEEIFSLTIGEPQFPTPTNIIQSWQSNASLLNKYPK
CCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
SSGEDELKDAQLHFINKRYNLTLTKSQIIPTLGTREVLFNFPQFYLFDLPQPTIAYPNPF
CCCCHHHHHHHEEEEECEEEEEEEHHHCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCH
YQIYEGAAIASKAQVLLMNLTSENDFTPSLTPKELKKVHLVILNSPNNPTGRILDMQALT
HHHHCCCHHHCCCEEEEEEECCCCCCCCCCCHHHHCEEEEEEEECCCCCCCCEEEHHHHH
EWVKKALEYDFVIINDECYSEIYESSPPPSILQASIQAGNTSFKNIIALNSISKRSSAPG
HHHHHHHCCCEEEECHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHEEEECCCHHCCCCCC
LRSGFIAGDAEILKAYNLYRTYLGCALPLPLQKAAAVAWKDMQTPESIRHIYAKNLALAR
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EILELSTEQISPYTFYVWLKVDNDEAFCKFAYEKKGVLTLPGSYLGRENQGKGYVRIALV
HHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCCEEECCCHHCCCCCCCCCEEEEEEE
YDNNTTKKALLALKEAIKLYKQECQ
ECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLHQFESYPFEKLRTLLAHSSPPSGEEIFSLTIGEPQFPTPTNIIQSWQSNASLLNKYPK
CCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
SSGEDELKDAQLHFINKRYNLTLTKSQIIPTLGTREVLFNFPQFYLFDLPQPTIAYPNPF
CCCCHHHHHHHEEEEECEEEEEEEHHHCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCH
YQIYEGAAIASKAQVLLMNLTSENDFTPSLTPKELKKVHLVILNSPNNPTGRILDMQALT
HHHHCCCHHHCCCEEEEEEECCCCCCCCCCCHHHHCEEEEEEEECCCCCCCCEEEHHHHH
EWVKKALEYDFVIINDECYSEIYESSPPPSILQASIQAGNTSFKNIIALNSISKRSSAPG
HHHHHHHCCCEEEECHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHEEEECCCHHCCCCCC
LRSGFIAGDAEILKAYNLYRTYLGCALPLPLQKAAAVAWKDMQTPESIRHIYAKNLALAR
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EILELSTEQISPYTFYVWLKVDNDEAFCKFAYEKKGVLTLPGSYLGRENQGKGYVRIALV
HHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCCEEECCCHHCCCCCCCCCEEEEEEE
YDNNTTKKALLALKEAIKLYKQECQ
ECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]