Click here to switch to the map view.

The map label for this gene is norM [H]

Identifier: 32265530

GI number: 32265530

Start: 35415

End: 36701

Strand: Direct

Name: norM [H]

Synonym: HH0031

Alternate gene names: 32265530

Gene position: 35415-36701 (Clockwise)

Preceding gene: 32265529

Following gene: 32265540

Centisome position: 1.97

GC content: 38.77

Gene sequence:

>1287_bases
TTGCTTGATATTGCTAATATCGCCATAGGAATGTATTTTATTGCTCATATTTCACCCGATTCTGAAGTTACAAAACATAA
TATCGTGGCACTTGGACTCGGTATGAATTGCTGGATGTTTCTCTTTGCACTCACAACCATTTTTTATGTAGGCACAAACG
CACAAGTCTCGCGTGCATTTGGAGAGAGAAATAACCTTAAAGCGGGACAGATTCTAAGCACAATGAGCATCGGGGCTGGG
CTTTGCTCTATTCCTATTTATGCACTTGCATATGTAAGCAATGAGTTGTATTTTGACTGGATGGGTGTGAGTGGGGAAAC
CAAAGAGCTAGGTATGTTGTATTTAGGTTGGATTTTTTATGGGATTCCCGCACTTTTTCTTAAGACAATATTTATTTCTG
CACTTTCAGCCGTAGGCGATACTAAAAGCGTTTTTTTTGTAAAAATCATCGCTACAAGCTTAAATATTGTCCTTAATTTT
ATGCTTATTTTTGGGGTGGAAAAGCTTGGTATTCCACCATTTGGTATTATGGGAGCTGGCATAGCAAATGTTATCATTAC
TTATTTCGAAGGGCTAGTTTTACTTGGCATTCTCTGTGGGCTACACCGCCATTTGACATTTTCACCCACCTTTAAATGGC
ATACGCTTTATAATGGATTCCATATTGGTATTCCCTCTGGCCTTGAGCGAGGCTTGACAATTTTTTCCCTTGTGCTTATT
ACAAAATTTATGACTGATTATGGTTTGGAAGTCATTGCTGGATTTCAAATTGGCTCAAGAGTGGAAAGCTTCATTTTTAT
GCCCGGTTTTGGATTCCAAGTGGCAGCAATGGCATTAGTTGGACAAATGCTCGGTGCAAAACGATTAGACTTAGCAGAAT
CTTTTATCAAAACAATTTTACTTATCTCATCAGTAGTTATGGGCATATTAGGTATAGGATTATGTATGCTGGGCAAAGAA
CTCTCCGCTATTTTTAGCACAGAAACAGAGGTGATTCATTACTCTTTTGATTATCTCCTTGCAGTAGGGCTTTCTCAAGT
GCCCCTTATTTGTATTTTTGTGCTTGATGGAGCATTGCGAGGAAGCGGTGCAACGAAGCTTTCTCTGTGGATTAACACAG
GGAGCATTTGGGTTTTGAGGATTCTCCCAATGTGGCTGTGTGTGCATTATAACATTGCAGTAGGATATATTTTTGCTATT
ATTTGCTGTGAAACATATTTGCGTGCAGGTATCTTTGGCTTTGTTTTTTACAAAGGCTTATGGAAGAAATATATCGCACG
ATTGTAA

Upstream 100 bases:

>100_bases
AAACACACACCAACACTACAAAGAGTCTTTGATGACATATAACTTCAAGCAACGTCTCCGCAAGATTCTAAGTATTGCCT
TGCCCTCTGGAGGAAACTCT

Downstream 100 bases:

>100_bases
AATAAGATTATTTTAAACAATAAAATACATACAGAATAAAAATTTTGACGCCTAAAATGCACAAACTATCTAAAAGACTT
AAATGCAAATAATTCATTCT

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MLDIANIAIGMYFIAHISPDSEVTKHNIVALGLGMNCWMFLFALTTIFYVGTNAQVSRAFGERNNLKAGQILSTMSIGAG
LCSIPIYALAYVSNELYFDWMGVSGETKELGMLYLGWIFYGIPALFLKTIFISALSAVGDTKSVFFVKIIATSLNIVLNF
MLIFGVEKLGIPPFGIMGAGIANVIITYFEGLVLLGILCGLHRHLTFSPTFKWHTLYNGFHIGIPSGLERGLTIFSLVLI
TKFMTDYGLEVIAGFQIGSRVESFIFMPGFGFQVAAMALVGQMLGAKRLDLAESFIKTILLISSVVMGILGIGLCMLGKE
LSAIFSTETEVIHYSFDYLLAVGLSQVPLICIFVLDGALRGSGATKLSLWINTGSIWVLRILPMWLCVHYNIAVGYIFAI
ICCETYLRAGIFGFVFYKGLWKKYIARL

Sequences:

>Translated_428_residues
MLDIANIAIGMYFIAHISPDSEVTKHNIVALGLGMNCWMFLFALTTIFYVGTNAQVSRAFGERNNLKAGQILSTMSIGAG
LCSIPIYALAYVSNELYFDWMGVSGETKELGMLYLGWIFYGIPALFLKTIFISALSAVGDTKSVFFVKIIATSLNIVLNF
MLIFGVEKLGIPPFGIMGAGIANVIITYFEGLVLLGILCGLHRHLTFSPTFKWHTLYNGFHIGIPSGLERGLTIFSLVLI
TKFMTDYGLEVIAGFQIGSRVESFIFMPGFGFQVAAMALVGQMLGAKRLDLAESFIKTILLISSVVMGILGIGLCMLGKE
LSAIFSTETEVIHYSFDYLLAVGLSQVPLICIFVLDGALRGSGATKLSLWINTGSIWVLRILPMWLCVHYNIAVGYIFAI
ICCETYLRAGIFGFVFYKGLWKKYIARL
>Mature_428_residues
MLDIANIAIGMYFIAHISPDSEVTKHNIVALGLGMNCWMFLFALTTIFYVGTNAQVSRAFGERNNLKAGQILSTMSIGAG
LCSIPIYALAYVSNELYFDWMGVSGETKELGMLYLGWIFYGIPALFLKTIFISALSAVGDTKSVFFVKIIATSLNIVLNF
MLIFGVEKLGIPPFGIMGAGIANVIITYFEGLVLLGILCGLHRHLTFSPTFKWHTLYNGFHIGIPSGLERGLTIFSLVLI
TKFMTDYGLEVIAGFQIGSRVESFIFMPGFGFQVAAMALVGQMLGAKRLDLAESFIKTILLISSVVMGILGIGLCMLGKE
LSAIFSTETEVIHYSFDYLLAVGLSQVPLICIFVLDGALRGSGATKLSLWINTGSIWVLRILPMWLCVHYNIAVGYIFAI
ICCETYLRAGIFGFVFYKGLWKKYIARL

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=389, Percent_Identity=22.107969151671, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47028; Mature: 47028

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIANIAIGMYFIAHISPDSEVTKHNIVALGLGMNCWMFLFALTTIFYVGTNAQVSRAF
CCCHHHHHHHHHHHEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHH
GERNNLKAGQILSTMSIGAGLCSIPIYALAYVSNELYFDWMGVSGETKELGMLYLGWIFY
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
GIPALFLKTIFISALSAVGDTKSVFFVKIIATSLNIVLNFMLIFGVEKLGIPPFGIMGAG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IANVIITYFEGLVLLGILCGLHRHLTFSPTFKWHTLYNGFHIGIPSGLERGLTIFSLVLI
HHHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEEECCEEECCCCHHHHHHHHHHHHHH
TKFMTDYGLEVIAGFQIGSRVESFIFMPGFGFQVAAMALVGQMLGAKRLDLAESFIKTIL
HHHHHHCCHHHEECCHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LISSVVMGILGIGLCMLGKELSAIFSTETEVIHYSFDYLLAVGLSQVPLICIFVLDGALR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCC
GSGATKLSLWINTGSIWVLRILPMWLCVHYNIAVGYIFAIICCETYLRAGIFGFVFYKGL
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WKKYIARL
HHHHHHCC
>Mature Secondary Structure
MLDIANIAIGMYFIAHISPDSEVTKHNIVALGLGMNCWMFLFALTTIFYVGTNAQVSRAF
CCCHHHHHHHHHHHEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHH
GERNNLKAGQILSTMSIGAGLCSIPIYALAYVSNELYFDWMGVSGETKELGMLYLGWIFY
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
GIPALFLKTIFISALSAVGDTKSVFFVKIIATSLNIVLNFMLIFGVEKLGIPPFGIMGAG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IANVIITYFEGLVLLGILCGLHRHLTFSPTFKWHTLYNGFHIGIPSGLERGLTIFSLVLI
HHHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEEECCEEECCCCHHHHHHHHHHHHHH
TKFMTDYGLEVIAGFQIGSRVESFIFMPGFGFQVAAMALVGQMLGAKRLDLAESFIKTIL
HHHHHHCCHHHEECCHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LISSVVMGILGIGLCMLGKELSAIFSTETEVIHYSFDYLLAVGLSQVPLICIFVLDGALR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCC
GSGATKLSLWINTGSIWVLRILPMWLCVHYNIAVGYIFAIICCETYLRAGIFGFVFYKGL
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WKKYIARL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]