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The map label for this gene is ppiD

Identifier: 30995417

GI number: 30995417

Start: 1067898

End: 1068025

Strand: Direct

Name: ppiD

Synonym: HI1004

Alternate gene names: 30995417

Gene position: 1067898-1068025 (Clockwise)

Preceding gene: 16272938

Following gene: 16272940

Centisome position: 58.35

GC content: 29.69

Gene sequence:

>1870_bases
ATGTTAATTGAAAAAATGCACAATTTAACAAACTCAAAGATTTCTAAATTTATCTTAGGTTTGATTGCTGTATCGTTTTT
AGTTGGTGGAATGTCTGGCTATCTTTTTAGCTCAAATGATACCTATGCCGGCAAAAGTGAACGGCGAAGTAATTTCTCAA
CAAGATTTTTTAAATCGCTATAATCAAGAGTTTGAAATACGCGCACAACGTGAGGGAGAGGCGTTTGTGGCTCAGTCTGA
TTCTCCTGAATTTGTTACCGCACTTCGTCAAAACATCGTTAATCTAATGATTGATCAAGAATTACTTCGCCAATATGTTA
AAGAATTAAAATTAGGCGTGAGTGATGAAATGATTAAACGTGCAATCGTGACCGATCCTAATTTTCAAGTAAAGGGTAAA
TTTGATAATGCTGTTTATCAACGAATATTACAACAAAATCATTTAACTTCAGATGGTTACGCTTCAATTTTACGTGCTTC
GTTACCTCTTGAACAAATACAAAATGGCGTTGCTAACAGTGAATTTATTGTTCCTGCTCAAGTAAAAAATAGCGCAGAAG
TTTTCTTTCAAAAGCGTTTAGCTCGTTTAGCAACTTTATCTCTTGCAGATGAAATGGCAAAACAATCAGTCTCTGATGAT
GAAATCAAAACGTATTATGAAGCTAATCAAAAGTCTTTTGTTCAGCCAGAGCAGGTTAAAGTTCAGTATATTGATCTTTC
TGCAGATAACATCAGTAGAAATCTTCAAGTTACAGATGTAGAAATTGCGCAATATTATCAAGATAATAAAGCACAATTTA
TGACTCAACATTTAGCTCATATTCAATTTGCAAATGAACAAGATGCGAAAGTGGCTTACGAGGAATTACAGAAAGGGGCA
AATTTCGCTGATGTCGCTAAAGCGAAATCTTTGGATAAAATTTCTGGTGAGAATGGCGGGGATTTAGGCTGGGTAAATGA
GAATGAATTACCAAAAGCCTTTGAAGATGCCGCAGCTGCATTGCAGGTAGGGCAATATAGCCAACCAATCAATGTGGATG
GCAATTACCATATTGTGTTAGTGCAAGAACGTAAAGCGCAAAGTTTGGAGAATGTGAAAGCTCAAATTGCAGATTTAGTT
CGTAAATCTTTGATGGAGAGTCGTTATTTTTCTTTAGAAAAACAAGCGAGTGATAAGGCTTTTGAAGACAGCAAGTCTCT
TAATACTGCAGCACAAGCAGCAGGTGTTAAGGTTCAAGAGAGCGATTATTTTTCTCGTCAAAATGTGCCAGCTGGATTAA
ATTTCCCTAATGTTATTTACACAATATTTGAATCAGATACTACGAATGTTGGTATGAATTCTGAACCAATTAATGTAGGC
GATTATCACACAATTATTGTACGTGTGTTGGATCGCAAAGCAGAGGGCGTAAAAAGTTTAGAAGAGGCTAAAATAGATAT
TGAAACTTTCTTAAAACGTCAGAAAGCTGAGAATGCGCTTAATGGAAAAGCACAACAAGCAGTGAAAAAATTAAGTGAAA
ACCCTGAATCAAAAGTAGATGGCATTAATTTCTCAAGTGAGCAGACTTTTACTTTAAGTGAAAATAAAGATCCTATTTTA
ACAAATGGTATATTTTCAATTGCTAAACCTGAATCAAGTAAAGCTCTTTATCAAGTGGTGCATAATTCAAATGGCGATGT
CGTTGTTGTCGCTTTGAATAAGGTTGAACAAGGCAGTTTAAGTGAAAAAGAATTGTCGCAATTTGCTATGCAATTATTGC
GTAGTCATCAATCTGAATTACAAGTTCAGTTAATACAAGGATTACGTGAGAGAGCGAAAATTGAGGTAAATGATTCTTTC
ATCAATCAAGATGATGAAGCACAACAATAG

Upstream 100 bases:

>100_bases
GCTGGCTTTGTGAGGATGGAGTTTTCACTTTTTAAGATGCTAATTTTTTACGTTTAGATTATAATCGGGAAAATTTTATA
TTTATAACAAGGGTTATAGA

Downstream 100 bases:

>100_bases
TAGGTTAAATTATAATTTGAGATAAATTCTGCTCAAAAGTGCGGTAAATTTCACCGCACTTTTTTACTTTTGTGCGAAAG
GAAGTTAATGATGTTCGGGA

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D

Number of amino acids: Translated: 43; Mature: 43

Protein sequence:

>622_residues
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYAAKVNGEVISQQDFLNRYNQEFEIRAQREGEAFVAQSD
SPEFVTALRQNIVNLMIDQELLRQYVKELKLGVSDEMIKRAIVTDPNFQVKGKFDNAVYQRILQQNHLTSDGYASILRAS
LPLEQIQNGVANSEFIVPAQVKNSAEVFFQKRLARLATLSLADEMAKQSVSDDEIKTYYEANQKSFVQPEQVKVQYIDLS
ADNISRNLQVTDVEIAQYYQDNKAQFMTQHLAHIQFANEQDAKVAYEELQKGANFADVAKAKSLDKISGENGGDLGWVNE
NELPKAFEDAAAALQVGQYSQPINVDGNYHIVLVQERKAQSLENVKAQIADLVRKSLMESRYFSLEKQASDKAFEDSKSL
NTAAQAAGVKVQESDYFSRQNVPAGLNFPNVIYTIFESDTTNVGMNSEPINVGDYHTIIVRVLDRKAEGVKSLEEAKIDI
ETFLKRQKAENALNGKAQQAVKKLSENPESKVDGINFSSEQTFTLSENKDPILTNGIFSIAKPESSKALYQVVHNSNGDV
VVVALNKVEQGSLSEKELSQFAMQLLRSHQSELQVQLIQGLRERAKIEVNDSFINQDDEAQQ

Sequences:

>Translated_43_residues
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYA
>Mature_43_residues
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYA

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPID_HAEIN (P44092)

Other databases:

- EMBL:   L42023
- PIR:   B64018
- RefSeq:   NP_439165.2
- ProteinModelPortal:   P44092
- GeneID:   950512
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1004
- NMPDR:   fig|71421.1.peg.968
- TIGR:   HI_1004
- HOGENOM:   HBG731256
- OMA:   TPEFQVD
- ProtClustDB:   CLSK870683
- BioCyc:   HINF71421:HI_1004-MONOMER
- BRENDA:   5.2.1.8
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 4713; Mature: 4713

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdca32e4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCH
>Mature Secondary Structure
MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800