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The map label for this gene is tdk [H]

Identifier: 30995383

GI number: 30995383

Start: 552193

End: 552744

Strand: Reverse

Name: tdk [H]

Synonym: HI0529

Alternate gene names: 30995383

Gene position: 552744-552193 (Counterclockwise)

Preceding gene: 16272474

Following gene: 16272472

Centisome position: 30.2

GC content: 37.68

Gene sequence:

>552_bases
ATGAACGCTGGAAAATCAACGACGTTGCTACAATCTTCCTATAACTATCGTGAGCGTGATATGAACACATTAGTTTATAC
GGCTGCGATTGATGATCGTTTTGGCGTGGGAAAAGTCACATCGCGTATTGGCATTTCGCAAGATGCCTTTTTATTTCGCT
CGGAAACCAATTTGTTTGATGAAATTAATGAGCATTTAAAAAAAGAAAAAGTGCATTGCGTGTTGGTGGATGAAGCTCAA
TTTCTTAGCAAACAACAAGTTTACCAGTTGAGTGATGTTGTTGATAAACTCAAAATCCCTGTGCTTTGTTATGGCTTGCG
TACAGATTTCCAAGCGGAACTTTTTGAAGGAAGTAAATATTTACTGGCTTGGGCGGATCAACTCGAAGAATTAAAAACAA
TTTGTTATTGTGGCCGCAAGGCTAATTTTGTTTTGCGTTTAAATGATCAGGGCGAGGTCATTAAAGAAGGTGCACAAATT
CAAATTGGAGGCAATGATTCTTATCTTTCTGTTTGCCGTTTACACTATAAAGAAAAGTGCGGTCAAATTTAA

Upstream 100 bases:

>100_bases
ATAGCGATCTGGCTATTGATGTTAAACCTCGTTGGGCAATGGCGGAATTACCGGCAATTTAGGAGAAAAAATGGCGAAAC
TCTACTTCTATTACTCCACA

Downstream 100 bases:

>100_bases
ATTAGTTTTTAAACACAACATTATAAGGACAATTTTATGCTAAAAAACAAAACTTTTGGGAGTGCGCTGATTATTGCAGG
CACAACCATTGGAGCAGGTA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MNAGKSTTLLQSSYNYRERDMNTLVYTAAIDDRFGVGKVTSRIGISQDAFLFRSETNLFDEINEHLKKEKVHCVLVDEAQ
FLSKQQVYQLSDVVDKLKIPVLCYGLRTDFQAELFEGSKYLLAWADQLEELKTICYCGRKANFVLRLNDQGEVIKEGAQI
QIGGNDSYLSVCRLHYKEKCGQI

Sequences:

>Translated_183_residues
MNAGKSTTLLQSSYNYRERDMNTLVYTAAIDDRFGVGKVTSRIGISQDAFLFRSETNLFDEINEHLKKEKVHCVLVDEAQ
FLSKQQVYQLSDVVDKLKIPVLCYGLRTDFQAELFEGSKYLLAWADQLEELKTICYCGRKANFVLRLNDQGEVIKEGAQI
QIGGNDSYLSVCRLHYKEKCGQI
>Mature_183_residues
MNAGKSTTLLQSSYNYRERDMNTLVYTAAIDDRFGVGKVTSRIGISQDAFLFRSETNLFDEINEHLKKEKVHCVLVDEAQ
FLSKQQVYQLSDVVDKLKIPVLCYGLRTDFQAELFEGSKYLLAWADQLEELKTICYCGRKANFVLRLNDQGEVIKEGAQI
QIGGNDSYLSVCRLHYKEKCGQI

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=178, Percent_Identity=67.9775280898876, Blast_Score=258, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 20909; Mature: 20909

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAGKSTTLLQSSYNYRERDMNTLVYTAAIDDRFGVGKVTSRIGISQDAFLFRSETNLFD
CCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEECCCHHHH
EINEHLKKEKVHCVLVDEAQFLSKQQVYQLSDVVDKLKIPVLCYGLRTDFQAELFEGSKY
HHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCEE
LLAWADQLEELKTICYCGRKANFVLRLNDQGEVIKEGAQIQIGGNDSYLSVCRLHYKEKC
EHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHC
GQI
CCC
>Mature Secondary Structure
MNAGKSTTLLQSSYNYRERDMNTLVYTAAIDDRFGVGKVTSRIGISQDAFLFRSETNLFD
CCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCEEEECCCHHHH
EINEHLKKEKVHCVLVDEAQFLSKQQVYQLSDVVDKLKIPVLCYGLRTDFQAELFEGSKY
HHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCEE
LLAWADQLEELKTICYCGRKANFVLRLNDQGEVIKEGAQIQIGGNDSYLSVCRLHYKEKC
EHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHC
GQI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA