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The map label for this gene is udp

Identifier: 30995365

GI number: 30995365

Start: 313495

End: 314253

Strand: Direct

Name: udp

Synonym: HI0280

Alternate gene names: 30995365

Gene position: 313495-314253 (Clockwise)

Preceding gene: 16272233

Following gene: 16272241

Centisome position: 17.13

GC content: 41.11

Gene sequence:

>759_bases
ATGTCAGGCGTATTCCACCTAAACCTCACTAAAGCACAACTTAAAGGTGCAACACTCGCTATTGTTCCTGGCGATCCTGC
GCGTAGTGAGCGTATTGCGAAACAACTTGATAATCCAGAGTTTCTTACAAGCACGCGTGAATTTACATCGTGGTTAGGTT
ATATCAATGGTCAGCCTATTGTTGTATGTTCTACGGGTATTGGTGGCCCTTCAACATCAATTTGTGTGGAAGAACTTGCT
CAACTTGGTGTTCGCACTTTCTTACGTATTGGCACAACGGGTGCAATTCAACCGCACATTAATGTAGGCGATGTTCTTAT
CACAACTGCTGCTGTCCGCTTAGATGGTGCAAGCCATCATTTTGTACCATTAGAATATCCAGCTGTGGCAAACTTTGAAT
GTACAACCGCACTTTATAATGCCGCGAAAGCAAAAGGTATTGAGCCTTATGTAGGTGTAACCGTATCATCTGATACATTC
TATCCAGGTCAAGAACGTTACGATACTTATAGTGGTAAAGTATATCGTAATTACCAAGGTTTGCTTAAACAATGGCAAGA
TTTGAATGTCATGAATTACGAAATGGAATCTTCAACATTGTTTACTATGTGTAGCGCATTAGGTTTGCGTGCAGGAATGG
TTGCAGGCGTGATTGTAAACCGCACTCAACAAGAAATTCCAAATGAAGCAACGATAAAACAAACAGAAGAAAAAGCTGTG
TCTGTTGTGATCACAGCTGCACAAGCATTGTTAAGTTAA

Upstream 100 bases:

>100_bases
GAGAAAAAAATTTTCTAAAAATATTTTATTTCTTTTCTTGAAAATAAGATTTTTCCTAAGGGCGAAATCATCACGTTCAA
TGATAATAAGGAGATTTATT

Downstream 100 bases:

>100_bases
ATTAATATTTATTTGAAACAATAAAACTTTATTTTATTCTGCACCTTAATTAGATTTATTTTCTAACGAAGTAAGGTGCA
GATTTTTTATTAATAAACTG

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSGVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLTSTREFTSWLGYINGQPIVVCSTGIGGPSTSICVEELA
QLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHHFVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTF
YPGQERYDTYSGKVYRNYQGLLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATIKQTEEKAV
SVVITAAQALLS

Sequences:

>Translated_252_residues
MSGVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLTSTREFTSWLGYINGQPIVVCSTGIGGPSTSICVEELA
QLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHHFVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTF
YPGQERYDTYSGKVYRNYQGLLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATIKQTEEKAV
SVVITAAQALLS
>Mature_251_residues
SGVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLTSTREFTSWLGYINGQPIVVCSTGIGGPSTSICVEELAQ
LGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHHFVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTFY
PGQERYDTYSGKVYRNYQGLLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATIKQTEEKAVS
VVITAAQALLS

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790265, Length=250, Percent_Identity=72, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1790844, Length=210, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UDP_HAEIN (P43770)

Other databases:

- EMBL:   L42023
- PIR:   C64059
- RefSeq:   NP_438448.2
- ProteinModelPortal:   P43770
- SMR:   P43770
- GeneID:   950640
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0280
- NMPDR:   fig|71421.1.peg.263
- TIGR:   HI_0280
- HOGENOM:   HBG617197
- OMA:   MSDVFHL
- ProtClustDB:   PRK11178
- BioCyc:   HINF71421:HI_0280-MONOMER
- BRENDA:   2.4.2.3
- GO:   GO:0005737
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR01718

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.3

Molecular weight: Translated: 27254; Mature: 27123

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLTSTREFTSWLGYINGQPI
CCCEEEEEEEHHHHCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEE
VVCSTGIGGPSTSICVEELAQLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHH
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEEECCCCCC
FVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTFYPGQERYDTYSGKVYRNYQG
EEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCEEEECHHH
LLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATIKQTEEKAV
HHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHH
SVVITAAQALLS
HHHHHHHHHHCC
>Mature Secondary Structure 
SGVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLTSTREFTSWLGYINGQPI
CCEEEEEEEHHHHCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEE
VVCSTGIGGPSTSICVEELAQLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHH
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEEECCCCCC
FVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTFYPGQERYDTYSGKVYRNYQG
EEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCEEEECHHH
LLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATIKQTEEKAV
HHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHH
SVVITAAQALLS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800