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The map label for this gene is erfK [H]

Identifier: 308535396

GI number: 308535396

Start: 4525622

End: 4526944

Strand: Direct

Name: erfK [H]

Synonym: NA

Alternate gene names: 308535396

Gene position: 4525622-4526944 (Clockwise)

Preceding gene: 197120345

Following gene: 197120350

Centisome position: 98.06

GC content: 57.37

Gene sequence:

>1323_bases
ATGCATCGAATTTTAGATCCGCCAATCATCGAAAAAGCTCTTCGTCTTCTGTTTCTCTGCGCTCTCGTCCTGTTTCTCAA
CGGATGTGTCGCCATGCAGAGGGCTCCCGAGCAATCGTTGCTACCGCCGGTTCCCACGCAAAAGGAGATCGAGCGGAACG
TCTTCCCGGTAGCCGGAGGTGATGACGTGATCGGCACCTTGGCAGTGGTGAGGCTTGAAAAGGGGGACACCCTGCCCGAC
ATCGCCAGACACTTTAGCCTTGGGATCAACGCAATCAGCGCTGCCAACCCAGGTGTCGATGTATGGGTCCCTGAACCGGG
AAAGGAGGTCATCCTCCCTTTGAGTTTCATCCTCCCGGATGCTCCCCGGAAAGGCATCGTGATCAACTTGGCCACCATGC
GGCTTTTCCGTTTCAAGGAAGATGGTAAAGCGCAAGTGGTGTCGACCTACCCTGTCGGTGTCGGCACCGCGGAGCGCCCG
ACGCCTACAGGCAAAATGCGCATTGAACGCAAGACTGCCCTGCCCACTTGGCACGTACCCGCTTCAATTGCCGAGGATCA
TAGGAAAAAAGGAGATCTTCTCCCCGCGAAGGTTCCGCCGGGACCTGAGAACCCTTTGGGTGAGCGCGCGCTTTACCTGA
GCAAAGCGGGGTATCTGATTCATGGCACCAACAAGCCGGCCAGCATAGGTCTTAAGGCAACAAACGGGTGCCTGCGGCTC
TACCCCGAGAATGTGACGACGCTTTACGAGGAGACGCCGGTCAATACCCCGGTACTCATCGTCAACCAGCCGTATCTAGT
GGGGCAACGGGATGGGGTCCTTTATCTTGAGGCTCATGCGCCCCTGGAAAGCTCTGGTGCCCTGGAGTTGGAGAAGGTGA
CGGCAAGACTGAGGAAGTGGGAAAAGAGGTACGGACGCTCACTTGACTGGGAAAAAATCCGTAAAGTGCAAACCGAGGCC
AGAGGTGTCCCTGTCCCCATCTTGGCCTTTGGTCAGGATAAGGCAAAAGATAGCCTGAAGACCGTTAACGTCGAGCGCCC
GCTACAAATGTTCGGCGCGCCTGAGGTACCCGAGCTCAAACGGGATGCCTGGTATGTTTTGGCTGCCAATGTGGGCGGGG
AGATCGAGGCTCGGAGGCTGGCAGCCATTATCAACCACCAGGGGCCGCCCATCCCGGCACGGGTGCTGCCGCAAAGCAGC
AATAGCTACCATGTCATCGCCGGTCCTTTCGATAACGCCGGCTTGGCCAAAGAGGCGGTCAGGCGGCTGAAGCTCGACCT
GGAACTCGACGGCATAGTGATAGACCCGGTCAAGAAGATATAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: peptidoglycan L,D-transpeptidase lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:
NA

Sequences:

>Translated_440_residues
MHRILDPPIIEKALRLLFLCALVLFLNGCVAMQRAPEQSLLPPVPTQKEIERNVFPVAGGDDVIGTLAVVRLEKGDTLPD
IARHFSLGINAISAANPGVDVWVPEPGKEVILPLSFILPDAPRKGIVINLATMRLFRFKEDGKAQVVSTYPVGVGTAERP
TPTGKMRIERKTALPTWHVPASIAEDHRKKGDLLPAKVPPGPENPLGERALYLSKAGYLIHGTNKPASIGLKATNGCLRL
YPENVTTLYEETPVNTPVLIVNQPYLVGQRDGVLYLEAHAPLESSGALELEKVTARLRKWEKRYGRSLDWEKIRKVQTEA
RGVPVPILAFGQDKAKDSLKTVNVERPLQMFGAPEVPELKRDAWYVLAANVGGEIEARRLAAIINHQGPPIPARVLPQSS
NSYHVIAGPFDNAGLAKEAVRRLKLDLELDGIVIDPVKKI
>Mature_440_residues
MHRILDPPIIEKALRLLFLCALVLFLNGCVAMQRAPEQSLLPPVPTQKEIERNVFPVAGGDDVIGTLAVVRLEKGDTLPD
IARHFSLGINAISAANPGVDVWVPEPGKEVILPLSFILPDAPRKGIVINLATMRLFRFKEDGKAQVVSTYPVGVGTAERP
TPTGKMRIERKTALPTWHVPASIAEDHRKKGDLLPAKVPPGPENPLGERALYLSKAGYLIHGTNKPASIGLKATNGCLRL
YPENVTTLYEETPVNTPVLIVNQPYLVGQRDGVLYLEAHAPLESSGALELEKVTARLRKWEKRYGRSLDWEKIRKVQTEA
RGVPVPILAFGQDKAKDSLKTVNVERPLQMFGAPEVPELKRDAWYVLAANVGGEIEARRLAAIINHQGPPIPARVLPQSS
NSYHVIAGPFDNAGLAKEAVRRLKLDLELDGIVIDPVKKI

Specific function: Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YkuD family [H]

Homologues:

Organism=Escherichia coli, GI1788299, Length=279, Percent_Identity=35.84229390681, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1787040, Length=232, Percent_Identity=37.9310344827586, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1787356, Length=262, Percent_Identity=35.1145038167939, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787968, Length=286, Percent_Identity=32.1678321678322, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005490 [H]

Pfam domain/function: PF03734 YkuD [H]

EC number: NA

Molecular weight: Translated: 48228; Mature: 48228

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRILDPPIIEKALRLLFLCALVLFLNGCVAMQRAPEQSLLPPVPTQKEIERNVFPVAGG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHCCEECCCCC
DDVIGTLAVVRLEKGDTLPDIARHFSLGINAISAANPGVDVWVPEPGKEVILPLSFILPD
CHHEEEEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCEEEEEHHHCCC
APRKGIVINLATMRLFRFKEDGKAQVVSTYPVGVGTAERPTPTGKMRIERKTALPTWHVP
CCCCCEEEEEEHEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEHHCCCCCCCC
ASIAEDHRKKGDLLPAKVPPGPENPLGERALYLSKAGYLIHGTNKPASIGLKATNGCLRL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCEEEEEECCCEEEE
YPENVTTLYEETPVNTPVLIVNQPYLVGQRDGVLYLEAHAPLESSGALELEKVTARLRKW
CCCCCEEEECCCCCCCCEEEEECCEEEECCCCEEEEEECCCCCCCCCEEHHHHHHHHHHH
EKRYGRSLDWEKIRKVQTEARGVPVPILAFGQDKAKDSLKTVNVERPLQMFGAPEVPELK
HHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHCCCEEECCCCHHHHCCCCCCCCCC
RDAWYVLAANVGGEIEARRLAAIINHQGPPIPARVLPQSSNSYHVIAGPFDNAGLAKEAV
CCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEECCCCCCCEEEEECCCCCCCHHHHHH
RRLKLDLELDGIVIDPVKKI
HHHEEEEEECCEEECCHHCC
>Mature Secondary Structure
MHRILDPPIIEKALRLLFLCALVLFLNGCVAMQRAPEQSLLPPVPTQKEIERNVFPVAGG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHCCEECCCCC
DDVIGTLAVVRLEKGDTLPDIARHFSLGINAISAANPGVDVWVPEPGKEVILPLSFILPD
CHHEEEEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCEEEEEHHHCCC
APRKGIVINLATMRLFRFKEDGKAQVVSTYPVGVGTAERPTPTGKMRIERKTALPTWHVP
CCCCCEEEEEEHEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEHHCCCCCCCC
ASIAEDHRKKGDLLPAKVPPGPENPLGERALYLSKAGYLIHGTNKPASIGLKATNGCLRL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCEEEEEECCCEEEE
YPENVTTLYEETPVNTPVLIVNQPYLVGQRDGVLYLEAHAPLESSGALELEKVTARLRKW
CCCCCEEEECCCCCCCCEEEEECCEEEECCCCEEEEEECCCCCCCCCEEHHHHHHHHHHH
EKRYGRSLDWEKIRKVQTEARGVPVPILAFGQDKAKDSLKTVNVERPLQMFGAPEVPELK
HHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHCCCEEECCCCHHHHCCCCCCCCCC
RDAWYVLAANVGGEIEARRLAAIINHQGPPIPARVLPQSSNSYHVIAGPFDNAGLAKEAV
CCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEECCCCCCCEEEEECCCCCCCHHHHHH
RRLKLDLELDGIVIDPVKKI
HHHEEEEEECCEEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592411; 9097040; 9278503; 9298646 [H]