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The map label for this gene is galE [H]

Identifier: 308535254

GI number: 308535254

Start: 1885690

End: 1886661

Strand: Direct

Name: galE [H]

Synonym: NA

Alternate gene names: 308535254

Gene position: 1885690-1886661 (Clockwise)

Preceding gene: 197118011

Following gene: 197118013

Centisome position: 40.86

GC content: 58.74

Gene sequence:

>972_bases
ATGAGAGTTTTGGTTACCGGAGCCACTGGATTTGTTGGCTGTATGCTGTGCAGGAGGCTCATCGCCGAAGGAACGGAGGT
TCGCGGTACGTTGCTGCCGTCTGAAGACCCGAAGTGTTTGCAGCAAGGCGTACTCCCGGTGACTGTTGAACCACTCAGCG
GCCACACGTCATGGAGCCATGCCCTGGCGGGCATTGACACGATAATCCATCTGGCGGCGCGGGTGCATATCATGGACGAT
CCAGCGGCGGATCCGCTGGTAGAGTTTCGCCGGGTGAATGTCGAGGGAACCGTCCGCCTGGCTAGGGAAGCCGCGCAGTC
GGGGGTGAAGAGGCTTGTATTTGTCAGCTCCGTCAAAGTGAATGGCGAAGAAACGGCGGATCCTTATTGTGCCGATTCCC
TCCCTGCCCCCACCGACCCGTACGGCATCAGCAAATGGGAGGCCGAACAGGCCATCCGGAAGATAGAGGCTGAAACCGGT
TTGGAGGTCGTCGTGGTGAGACCGACCCTCGTCTACGGTCCCGGGGTCAAGGCCAACTTCCTCAACATGCTGAACGTGGT
GAGCCTAGGGATCCCACTTCCGCTGGCAAGTATCGCTAACAGGCGCAGCCTGATCTATGTCGGCAATCTCGCTGACGCCC
TTGCGACCTGCGCTTCGCATCCAACTGCAGCAGGAAAGACGTTCCTGGTCAGTGATGACGACGATGTCTCTACGCCGGAG
TTGATCAGAAGGACAGCAAAGGCTCTGGATGCGCCGGTGCGGCTCGTACCGTTTCCTCCTGGGCTTATGTTGTGCGCAGC
CAGCGTCACCGGGAAAACCGGCGCCGTGACTCGGCTCACTGGGTCGCTTACGGTGGATATCAGCAGCATCAAAGAACTGC
TCGGGTGGCAGCCGTCGTTTTCCATGGATGAGGGTTTGCGGGAGACGGCTCAATGGTTCAAGAGACAACGGAAGGAAAGG
TGGAATGCATGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: NAD-dependent nucleoside diphosphate-sugar epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:
NA

Sequences:

>Translated_323_residues
MRVLVTGATGFVGCMLCRRLIAEGTEVRGTLLPSEDPKCLQQGVLPVTVEPLSGHTSWSHALAGIDTIIHLAARVHIMDD
PAADPLVEFRRVNVEGTVRLAREAAQSGVKRLVFVSSVKVNGEETADPYCADSLPAPTDPYGISKWEAEQAIRKIEAETG
LEVVVVRPTLVYGPGVKANFLNMLNVVSLGIPLPLASIANRRSLIYVGNLADALATCASHPTAAGKTFLVSDDDDVSTPE
LIRRTAKALDAPVRLVPFPPGLMLCAASVTGKTGAVTRLTGSLTVDISSIKELLGWQPSFSMDEGLRETAQWFKRQRKER
WNA
>Mature_323_residues
MRVLVTGATGFVGCMLCRRLIAEGTEVRGTLLPSEDPKCLQQGVLPVTVEPLSGHTSWSHALAGIDTIIHLAARVHIMDD
PAADPLVEFRRVNVEGTVRLAREAAQSGVKRLVFVSSVKVNGEETADPYCADSLPAPTDPYGISKWEAEQAIRKIEAETG
LEVVVVRPTLVYGPGVKANFLNMLNVVSLGIPLPLASIANRRSLIYVGNLADALATCASHPTAAGKTFLVSDDDDVSTPE
LIRRTAKALDAPVRLVPFPPGLMLCAASVTGKTGAVTRLTGSLTVDISSIKELLGWQPSFSMDEGLRETAQWFKRQRKER
WNA

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786974, Length=361, Percent_Identity=27.4238227146814, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081792, Length=345, Percent_Identity=23.4782608695652, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17568069, Length=258, Percent_Identity=27.906976744186, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71987463, Length=192, Percent_Identity=31.25, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34745; Mature: 34745

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVTGATGFVGCMLCRRLIAEGTEVRGTLLPSEDPKCLQQGVLPVTVEPLSGHTSWSH
CEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCEEEECCCCCCCHHHH
ALAGIDTIIHLAARVHIMDDPAADPLVEFRRVNVEGTVRLAREAAQSGVKRLVFVSSVKV
HHHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEEEEE
NGEETADPYCADSLPAPTDPYGISKWEAEQAIRKIEAETGLEVVVVRPTLVYGPGVKANF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECEEEECCCCCHHH
LNMLNVVSLGIPLPLASIANRRSLIYVGNLADALATCASHPTAAGKTFLVSDDDDVSTPE
HHHHHHHHHCCCCCHHHHCCCCCEEEECCHHHHHHHHHCCCCCCCCEEEECCCCCCCCHH
LIRRTAKALDAPVRLVPFPPGLMLCAASVTGKTGAVTRLTGSLTVDISSIKELLGWQPSF
HHHHHHHHHCCCEEEEECCCCHHEEEHHCCCCCCCEEEEECEEEEEHHHHHHHHCCCCCC
SMDEGLRETAQWFKRQRKERWNA
CHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVLVTGATGFVGCMLCRRLIAEGTEVRGTLLPSEDPKCLQQGVLPVTVEPLSGHTSWSH
CEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCEEEECCCCCCCHHHH
ALAGIDTIIHLAARVHIMDDPAADPLVEFRRVNVEGTVRLAREAAQSGVKRLVFVSSVKV
HHHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEEEEE
NGEETADPYCADSLPAPTDPYGISKWEAEQAIRKIEAETGLEVVVVRPTLVYGPGVKANF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECEEEECCCCCHHH
LNMLNVVSLGIPLPLASIANRRSLIYVGNLADALATCASHPTAAGKTFLVSDDDDVSTPE
HHHHHHHHHCCCCCHHHHCCCCCEEEECCHHHHHHHHHCCCCCCCCEEEECCCCCCCCHH
LIRRTAKALDAPVRLVPFPPGLMLCAASVTGKTGAVTRLTGSLTVDISSIKELLGWQPSF
HHHHHHHHHCCCEEEEECCCCHHEEEHHCCCCCCCEEEEECEEEEEHHHHHHHHCCCCCC
SMDEGLRETAQWFKRQRKERWNA
CHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8820651; 10521656 [H]