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The map label for this gene is accD5 [H]

Identifier: 308513341

GI number: 308513341

Start: 3619432

End: 3621042

Strand: Direct

Name: accD5 [H]

Synonym: NA

Alternate gene names: 308513341

Gene position: 3619432-3621042 (Clockwise)

Preceding gene: 39998387

Following gene: 308513342

Centisome position: 94.9

GC content: 61.7

Gene sequence:

>1611_bases
ATGAAAGAAGGTTACGACCTGATTCAGCGCCCCATCAAATCGGTCAGCATCGATCAGATCGAAAAGCAGCACTTCAAGAA
AAGGATGACCGTCTGGGAGCGGATCAAGGTGCTTAGCGACAAGGAGCCCAACGTTCTCTACCAGAACTGGGGCAAGAACC
TGGACGGCGCCTCGCTGGTGACCGCCATTCTCAATATCGGCGGCCGTGATGTGGCGGTATACGGCCACGACTTTACCGTA
CGCGCCGGGTCCATCGACGCCACCAACGGCAGCAAACTGGCCCGTCTCTTCAACATGGCCGGCGAAAAGGGGATTCCCCT
CATCGGCATGAACGACTCCGCAGGCGCCTTCGTTCCGGCCGGGGTCGGCGGTCTCGACGGCTATGCCGAGGCGTTCACGG
CGCTGCGCAAGATCAGCGGCGTAGTCCCCTCCATCATGTGCATGTTCGGCTTCAACGCCGGCGGCGGTTCCTACCTGCCG
CGGCAGGGGAGCTTCGTCATTCAGCCCGCCGACACCTTCTTCGGCCTCACCGGGCCCGGCGTCGTCAAATCGGTTCTCGG
CGAGGACATCACTCCCGATGAGCTTGGCGGCCCCAAGGTCCACGGCAAATCGGGCGTAGCCGACCTGACCGTCTCCGACG
AGGTAGCTGCCCTCCGGACAGCGGTCCGGCTCCTCTCCTACATCCCTGACAACAACAGCGTGGGCGCACCGTTCCAGGAA
ACCAGCGATCCTCTGAACCGCAAAACCTGGGAGATCAACACCCTCCTGAAAAAGGCCTTCAACTCGCCGACCGGCTTCAA
CACTCCGTTCGACGTCTCCATCATCATCCAGCAAATCTGTGACCATGGTGACTACTTCGAACTGCAGCCTGAACGGGCAA
AGGAAGCGGTAACGGCCTTCGGCCGCCTGGGGGGCCAAGTCGTGGGCTTCGTTGCCAACAACTCGGCCGTGGCTTCGGGT
CAGATCGACTGCGACTCGGCGGTGAAAATTGCCCGCTTCGTCCGGTTCTGCAACATCTACAACATCCCCATCATCTTCAT
GGAAGACACCACCGGCTTCCTGCCGGGTCGCGAACAGGAAAGCCGCGGCATTGTCCAGGCCGGCCGCTCCATGCTCGACG
CCATCGTCGACGTGCGCACCCCGCGAATCCTGCTGATTCTGCGCAACGCCTTCGGGGGCGCTTACGCCTCCTACAACAAC
TATCCCACCGGCGCCGACCTGGTGCTGGCCCTTCCCACCACCCGCCTCGCCGTCATGGGTCCTGCCGGCAAGGAATTCGT
CTACAAGGACGAGATCCGCAAGATCCGCGGCGCCGTTGCCGACATGGTCAAGAAGGGGGTTGAAGAGCGCACCAAGGCTG
GAATGGAGGCCGGTGCAGCCAAGAAGGATGCGGAGAAGGAAGCGGCCGAGTGGCTGAAGGGCCAGGAAGCCGCCCTGAAT
CAGCGGTACGAAAAAGAACTGATGAACCCGAAGGAAGGTCTGGCCCTGGGCTCCATCTCCTCCATCGTCATGCCGACCGA
TCTGCGCCAGGTACTCGGCGAAAACATCGCCTTCCTGATGCGGCACTACAAGCCGTCGCCCATGTGCGGCCCGCAGCGCG
AATTCCACTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: carboxyl transferase domain-containing protein

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:
NA

Sequences:

>Translated_536_residues
MKEGYDLIQRPIKSVSIDQIEKQHFKKRMTVWERIKVLSDKEPNVLYQNWGKNLDGASLVTAILNIGGRDVAVYGHDFTV
RAGSIDATNGSKLARLFNMAGEKGIPLIGMNDSAGAFVPAGVGGLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLP
RQGSFVIQPADTFFGLTGPGVVKSVLGEDITPDELGGPKVHGKSGVADLTVSDEVAALRTAVRLLSYIPDNNSVGAPFQE
TSDPLNRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDHGDYFELQPERAKEAVTAFGRLGGQVVGFVANNSAVASG
QIDCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQESRGIVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNN
YPTGADLVLALPTTRLAVMGPAGKEFVYKDEIRKIRGAVADMVKKGVEERTKAGMEAGAAKKDAEKEAAEWLKGQEAALN
QRYEKELMNPKEGLALGSISSIVMPTDLRQVLGENIAFLMRHYKPSPMCGPQREFH
>Mature_536_residues
MKEGYDLIQRPIKSVSIDQIEKQHFKKRMTVWERIKVLSDKEPNVLYQNWGKNLDGASLVTAILNIGGRDVAVYGHDFTV
RAGSIDATNGSKLARLFNMAGEKGIPLIGMNDSAGAFVPAGVGGLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLP
RQGSFVIQPADTFFGLTGPGVVKSVLGEDITPDELGGPKVHGKSGVADLTVSDEVAALRTAVRLLSYIPDNNSVGAPFQE
TSDPLNRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDHGDYFELQPERAKEAVTAFGRLGGQVVGFVANNSAVASG
QIDCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQESRGIVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNN
YPTGADLVLALPTTRLAVMGPAGKEFVYKDEIRKIRGAVADMVKKGVEERTKAGMEAGAAKKDAEKEAAEWLKGQEAALN
QRYEKELMNPKEGLALGSISSIVMPTDLRQVLGENIAFLMRHYKPSPMCGPQREFH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=443, Percent_Identity=36.7945823927765, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI295821216, Length=463, Percent_Identity=35.2051835853132, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI11545863, Length=462, Percent_Identity=27.2727272727273, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI134142062, Length=308, Percent_Identity=26.6233766233766, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI38679960, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38679974, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38679971, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679977, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679967, Length=355, Percent_Identity=24.5070422535211, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147362, Length=418, Percent_Identity=37.5598086124402, Blast_Score=271, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI25147359, Length=418, Percent_Identity=37.5598086124402, Blast_Score=271, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17552936, Length=499, Percent_Identity=25.8517034068136, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71997163, Length=295, Percent_Identity=23.0508474576271, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323863, Length=318, Percent_Identity=25.4716981132075, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324343, Length=318, Percent_Identity=24.5283018867925, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24586065, Length=467, Percent_Identity=25.9100642398287, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI161076407, Length=350, Percent_Identity=24.2857142857143, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24586460, Length=350, Percent_Identity=24.2857142857143, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI161076409, Length=350, Percent_Identity=24.2857142857143, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24586458, Length=350, Percent_Identity=24.2857142857143, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 58108; Mature: 58108

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEGYDLIQRPIKSVSIDQIEKQHFKKRMTVWERIKVLSDKEPNVLYQNWGKNLDGASLV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHH
TAILNIGGRDVAVYGHDFTVRAGSIDATNGSKLARLFNMAGEKGIPLIGMNDSAGAFVPA
HHHHHCCCCEEEEECCCEEEEECCEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
GVGGLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPADTFFGLTGPG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHCCCCCHH
VVKSVLGEDITPDELGGPKVHGKSGVADLTVSDEVAALRTAVRLLSYIPDNNSVGAPFQE
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHH
TSDPLNRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDHGDYFELQPERAKEAVTAF
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHH
GRLGGQVVGFVANNSAVASGQIDCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQE
HHCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHH
SRGIVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNNYPTGADLVLALPTTRLAVMG
HCHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCHHCCCCCCCCCCCEEEEECCCEEEEEC
PAGKEFVYKDEIRKIRGAVADMVKKGVEERTKAGMEAGAAKKDAEKEAAEWLKGQEAALN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHH
QRYEKELMNPKEGLALGSISSIVMPTDLRQVLGENIAFLMRHYKPSPMCGPQREFH
HHHHHHHCCHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKEGYDLIQRPIKSVSIDQIEKQHFKKRMTVWERIKVLSDKEPNVLYQNWGKNLDGASLV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHH
TAILNIGGRDVAVYGHDFTVRAGSIDATNGSKLARLFNMAGEKGIPLIGMNDSAGAFVPA
HHHHHCCCCEEEEECCCEEEEECCEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
GVGGLDGYAEAFTALRKISGVVPSIMCMFGFNAGGGSYLPRQGSFVIQPADTFFGLTGPG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHCCCCCHH
VVKSVLGEDITPDELGGPKVHGKSGVADLTVSDEVAALRTAVRLLSYIPDNNSVGAPFQE
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHH
TSDPLNRKTWEINTLLKKAFNSPTGFNTPFDVSIIIQQICDHGDYFELQPERAKEAVTAF
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHH
GRLGGQVVGFVANNSAVASGQIDCDSAVKIARFVRFCNIYNIPIIFMEDTTGFLPGREQE
HHCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHH
SRGIVQAGRSMLDAIVDVRTPRILLILRNAFGGAYASYNNYPTGADLVLALPTTRLAVMG
HCHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCHHCCCCCCCCCCCEEEEECCCEEEEEC
PAGKEFVYKDEIRKIRGAVADMVKKGVEERTKAGMEAGAAKKDAEKEAAEWLKGQEAALN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHH
QRYEKELMNPKEGLALGSISSIVMPTDLRQVLGENIAFLMRHYKPSPMCGPQREFH
HHHHHHHCCHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]