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The map label for this gene is pbpA [H]

Identifier: 308513321

GI number: 308513321

Start: 2696275

End: 2697288

Strand: Reverse

Name: pbpA [H]

Synonym: NA

Alternate gene names: 308513321

Gene position: 2697288-2696275 (Counterclockwise)

Preceding gene: 39997555

Following gene: 39997552

Centisome position: 70.72

GC content: 66.57

Gene sequence:

>1014_bases
GTGGCCCCCCTCGCGGGCGGAGGCACGGTGGTGTATGCCATCAATGAAGAGGTCCAGGAGCGGGTCAAGGACGTCCTGGC
CCAGTTCCAGGTTCCCTACGGGGTTTTCGTGGCGGTGGAGCCGCGCAGCGGCCGGATCCTGGCCATGGTGGCCCATTCCT
CGATCCTGCCGGGCTGGGAGCAGCAGGCGTTCTACGGCATCTACCCCATGGCGTCGCTGTTCAAGATCATTACCGCCACC
GCTGCCCTTGAACAGGGCAAGGTCTCTCCCGACACCGTGATTCCCTTCAGGGGGGGGCTCTACTCGGAGAGTTCCCGCCA
CTGGAGCGACCTGCCAAAGCGGGGCGCCCAGGAGATGGATCTGACCACCGCCATGGGAAAATCGGTGAACCCGGTCTTCG
GCCGGCTTGCCTGCGACGTGGCCGGGCGCGATTCGGTCCTTCGCTGCGCGGAGCGGTTCGGCTTCAACCATGCGCTGCTT
CCCGGCACGCCCGTCCTGCCCAGCAAGGCCGAGCACCCCGCCACCGACGACGATCTGCGCCTCATGGGGGCCGGGCTCGG
GCGCGAGGTGAAGATTTCGCCGCTCCATGCGGCGGTGCTGATGGCCACGGTTGCCAACGGCGGCACCATGCTCGTCCCCT
CCCTGGCTGACGAGATCCGCGACCCGTCGGGAAAGGTCGCCTATACCCACCAGCCCCGGCCGCTGCGGACCGTGACCACG
GCCGACGTTTCAGCGCAGCTCACGCGGATGCTGTCCTCCACCGTGACCACCGGCACTTCCCGCCGGGCGTTCCATGACCA
GCGCGGTCGACCCAAGCTGGCGGACATCTCCATTGCCGCCAAGACCGGTTCCATCAACGGTACCGACCCCGAGGGCCACT
ACAGCTGGTTCGCCGCCTATGCTCCCACCGACAACCCGCAAATAGCCCTGGCAGCCCTCGTCATCAACCAGGACAAGTGG
AAGATCAAGGCGTCCTACGTGGGCGAGCAGGCCTTGGAGGCCTTCTTCAAATAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: penicillin-binding protein

Products: NA

Alternate protein names: PBPA [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:
NA

Sequences:

>Translated_337_residues
MAPLAGGGTVVYAINEEVQERVKDVLAQFQVPYGVFVAVEPRSGRILAMVAHSSILPGWEQQAFYGIYPMASLFKIITAT
AALEQGKVSPDTVIPFRGGLYSESSRHWSDLPKRGAQEMDLTTAMGKSVNPVFGRLACDVAGRDSVLRCAERFGFNHALL
PGTPVLPSKAEHPATDDDLRLMGAGLGREVKISPLHAAVLMATVANGGTMLVPSLADEIRDPSGKVAYTHQPRPLRTVTT
ADVSAQLTRMLSSTVTTGTSRRAFHDQRGRPKLADISIAAKTGSINGTDPEGHYSWFAAYAPTDNPQIALAALVINQDKW
KIKASYVGEQALEAFFK
>Mature_336_residues
APLAGGGTVVYAINEEVQERVKDVLAQFQVPYGVFVAVEPRSGRILAMVAHSSILPGWEQQAFYGIYPMASLFKIITATA
ALEQGKVSPDTVIPFRGGLYSESSRHWSDLPKRGAQEMDLTTAMGKSVNPVFGRLACDVAGRDSVLRCAERFGFNHALLP
GTPVLPSKAEHPATDDDLRLMGAGLGREVKISPLHAAVLMATVANGGTMLVPSLADEIRDPSGKVAYTHQPRPLRTVTTA
DVSAQLTRMLSSTVTTGTSRRAFHDQRGRPKLADISIAAKTGSINGTDPEGHYSWFAAYAPTDNPQIALAALVINQDKWK
IKASYVGEQALEAFFK

Specific function: Cell wall formation. Plays an important role in cell division and cell shape maintenance by cross-linking adjacent peptidoglycan chains through transpeptidation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Probable). Note=Localized to the division site (septum) along with newly synthesized peptidoglycan, between segregated nucleoids (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 36247; Mature: 36116

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPLAGGGTVVYAINEEVQERVKDVLAQFQVPYGVFVAVEPRSGRILAMVAHSSILPGWE
CCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCC
QQAFYGIYPMASLFKIITATAALEQGKVSPDTVIPFRGGLYSESSRHWSDLPKRGAQEMD
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCHHH
LTTAMGKSVNPVFGRLACDVAGRDSVLRCAERFGFNHALLPGTPVLPSKAEHPATDDDLR
HHHHHCCCCCHHHHHHEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCE
LMGAGLGREVKISPLHAAVLMATVANGGTMLVPSLADEIRDPSGKVAYTHQPRPLRTVTT
EEECCCCCEEEECHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCCEEEECCCCCCEEEEE
ADVSAQLTRMLSSTVTTGTSRRAFHDQRGRPKLADISIAAKTGSINGTDPEGHYSWFAAY
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEE
APTDNPQIALAALVINQDKWKIKASYVGEQALEAFFK
CCCCCCCEEEEEEEEECCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
APLAGGGTVVYAINEEVQERVKDVLAQFQVPYGVFVAVEPRSGRILAMVAHSSILPGWE
CCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCC
QQAFYGIYPMASLFKIITATAALEQGKVSPDTVIPFRGGLYSESSRHWSDLPKRGAQEMD
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHCCCCHHH
LTTAMGKSVNPVFGRLACDVAGRDSVLRCAERFGFNHALLPGTPVLPSKAEHPATDDDLR
HHHHHCCCCCHHHHHHEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCE
LMGAGLGREVKISPLHAAVLMATVANGGTMLVPSLADEIRDPSGKVAYTHQPRPLRTVTT
EEECCCCCEEEECHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCCEEEECCCCCCEEEEE
ADVSAQLTRMLSSTVTTGTSRRAFHDQRGRPKLADISIAAKTGSINGTDPEGHYSWFAAY
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEE
APTDNPQIALAALVINQDKWKIKASYVGEQALEAFFK
CCCCCCCEEEEEEEEECCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA