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The map label for this gene is gdhB [H]

Identifier: 308513304

GI number: 308513304

Start: 1717831

End: 1719891

Strand: Direct

Name: gdhB [H]

Synonym: NA

Alternate gene names: 308513304

Gene position: 1717831-1719891 (Clockwise)

Preceding gene: 39996662

Following gene: 39996665

Centisome position: 45.04

GC content: 63.51

Gene sequence:

>2061_bases
ATGAGCGGCGAGGACGCCACCCTCACCAATGCCTTCATCGCCTTCTGTCATTCCAACCTGGCCCACAACCAGCCCGACCG
CTTCGGCCTTGACGACGTGCGCGGCGCCTTCCTGGCCCACCCCGAGATCGCGCTGCAGCTGGCAAAGCTCTTCCGGGCCC
GTTTCGACCCGGCCGTGGAGGGCCGGGCCGAGCTCTACGAGCGGGTGCTGGCCGAAACCCGGCGTGAGGTGGCGGATTAC
AACACCGGCCACCGCTACCTGGACGAGGTGCGCAGGACCATCTTCCACTGCTGCCTCACTTTCATCACCCGCACCCTGAA
GACCAACTTCTTCGTGCTGGAGAAACAGGCCCTGGCCTTCCGGCTCGACCCCGCCTACCTGACCGAGCTGGGTACTGATT
TTACCGCCGACCTGCCTCCGGCCATGCCCTTCCGAGTCACCTTTTTCTTCAGCCGCTTCGGATTCGGTTACCACATCGGT
TTCTCCGACATCGCCCGGGGAGGGTGGCGCACGGTCATCTGCCGTACCCCCGACGACCTGGTCACCAACGCCAATACCCT
GTTCCGGGAGAACTTCGTTCTGGCTCACACCCAGCACCTGAAGAACAAGGACATTTACGAGGGGGGCTCGAAGCTGGTGG
TGGCCCTGGATGCCTCGGACCTGAAAGCGAAGGACCGGCCCCTGGAGACCTGGCGCCTCTACAAGCTCCAGTACGGCATC
ACCGGCGCCTTCCTGGATATTTTTACCACCGACAACGGCGTGGCCCGGCATCCGGCAGTGGTGGACTACTACCGGGAGGA
CGAGCCCATCGAGCTCGGCCCCGACGAGAACATGCACGACAACATGATCGAGACCATCGCCTGGATGTCGAAACGGCGCG
GCTACATGCTCGGCATCGGGATCATGTCCAGCAAGCGGGTGGGGATCAACCACAAGGAGTACGGCGTCACCTCCACCGGC
GTAGTGGCGTTCGCCGAGATCACGATGGCGGAGCTGGGCATCGACATCCGGCGGGATCCGTTCACCGTCAAGTTCACCGG
CGGTCCCAACGGCGACGTGGCAGGGAACGCCCTCCGGATCATGCTGGAGCGCTGCCCCAAGGTGAAAATCGGCCTGATCC
TCGACGGTACGGCGGCCCTGTGCGACCCCGAGGGCGCGGATCACGGTGAGCTGGGCCGCATCCTGCTGAAGGAGGACCTG
GATGCCTTTGATCCGGCGGCGCTCCATCCGGGCGGGTTCATGCTGTTCCGCACCGGCAGCCGGCGCGAGGGGCTGCGGGA
GCTTTTCCGGCGCGTGATCAAAACCGATGCGGGGCTCGTGGAGGAGTGGATCTCACTGGACGAATTCTCCAAGGAGTTCG
GCGAGTTGATATTCAGCGTGCCGGCGGATCTCTTCATCCCCGCCGGCGGGCGCCCGGAAACAATCGATAAGGACAATTGG
GACCAATTCCTCCTGCCTGACGGCACCCCGTCGGCCAGGGCCATCGTGGAAGGGGCCAACTCTTTCATCACCCCGCCGGC
CCGCGTGGAGCTCCAGAAGAAGGGGATCATCGTCATGCGCGACGCCTCTGCCAACAAGTGCGGCGTCATTTCTTCATCCT
ACGAGATCATCGCCAACCTGCTCCTGACGGAGAAGGAATTCATGGAGCACAAGGAGCGCTACGTGGCCGACGTGCTCCGG
ATTCTGGAAAAGCGGGCCGGCGACGAGGCCCGGCTGATCCTGAAGCGCCGCCGGGAGCAGCCGGGAACCCTGTGCACCGA
GATATCGGACTCCCTGAGCACCGAGATCAACGCCAATTATGCACGGCTCTTCAGATTCTTCCAGGCCCGCCCTGAGCTCT
GCCTGCAGCCTCTCTACCGCCGGGCGATTCTGGCGCACCTGCCCAAGATCATTGCCGAGGAAGCCCGTTTCCGCCGCCGC
CTCACCCAACTGCCCCAGAAGTACCTGTCTGCCATTCTCGCCGCGGAGATCGGCTCGTCCATGGTCTATCGCGGCGACCG
GGAAACCGAGTTCGAGGACATGATCAAGCTCCACCTGATGCGCAGTTTTTCGGCTATATAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: Glu/Leu/Phe/Val dehydrogenase

Products: NA

Alternate protein names: NAD-GDH; NAD(+)-dependent glutamate dehydrogenase [H]

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:
NA

Sequences:

>Translated_686_residues
MSGEDATLTNAFIAFCHSNLAHNQPDRFGLDDVRGAFLAHPEIALQLAKLFRARFDPAVEGRAELYERVLAETRREVADY
NTGHRYLDEVRRTIFHCCLTFITRTLKTNFFVLEKQALAFRLDPAYLTELGTDFTADLPPAMPFRVTFFFSRFGFGYHIG
FSDIARGGWRTVICRTPDDLVTNANTLFRENFVLAHTQHLKNKDIYEGGSKLVVALDASDLKAKDRPLETWRLYKLQYGI
TGAFLDIFTTDNGVARHPAVVDYYREDEPIELGPDENMHDNMIETIAWMSKRRGYMLGIGIMSSKRVGINHKEYGVTSTG
VVAFAEITMAELGIDIRRDPFTVKFTGGPNGDVAGNALRIMLERCPKVKIGLILDGTAALCDPEGADHGELGRILLKEDL
DAFDPAALHPGGFMLFRTGSRREGLRELFRRVIKTDAGLVEEWISLDEFSKEFGELIFSVPADLFIPAGGRPETIDKDNW
DQFLLPDGTPSARAIVEGANSFITPPARVELQKKGIIVMRDASANKCGVISSSYEIIANLLLTEKEFMEHKERYVADVLR
ILEKRAGDEARLILKRRREQPGTLCTEISDSLSTEINANYARLFRFFQARPELCLQPLYRRAILAHLPKIIAEEARFRRR
LTQLPQKYLSAILAAEIGSSMVYRGDRETEFEDMIKLHLMRSFSAI
>Mature_685_residues
SGEDATLTNAFIAFCHSNLAHNQPDRFGLDDVRGAFLAHPEIALQLAKLFRARFDPAVEGRAELYERVLAETRREVADYN
TGHRYLDEVRRTIFHCCLTFITRTLKTNFFVLEKQALAFRLDPAYLTELGTDFTADLPPAMPFRVTFFFSRFGFGYHIGF
SDIARGGWRTVICRTPDDLVTNANTLFRENFVLAHTQHLKNKDIYEGGSKLVVALDASDLKAKDRPLETWRLYKLQYGIT
GAFLDIFTTDNGVARHPAVVDYYREDEPIELGPDENMHDNMIETIAWMSKRRGYMLGIGIMSSKRVGINHKEYGVTSTGV
VAFAEITMAELGIDIRRDPFTVKFTGGPNGDVAGNALRIMLERCPKVKIGLILDGTAALCDPEGADHGELGRILLKEDLD
AFDPAALHPGGFMLFRTGSRREGLRELFRRVIKTDAGLVEEWISLDEFSKEFGELIFSVPADLFIPAGGRPETIDKDNWD
QFLLPDGTPSARAIVEGANSFITPPARVELQKKGIIVMRDASANKCGVISSSYEIIANLLLTEKEFMEHKERYVADVLRI
LEKRAGDEARLILKRRREQPGTLCTEISDSLSTEINANYARLFRFFQARPELCLQPLYRRAILAHLPKIIAEEARFRRRL
TQLPQKYLSAILAAEIGSSMVYRGDRETEFEDMIKLHLMRSFSAI

Specific function: Involved in arginine catabolism by converting L- glutamate, into 2-oxoglutarate, which is then channeled into the tricarboxylic acid cycle. Can also utilize other amino acids of the glutamate family [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319986, Length=597, Percent_Identity=33.3333333333333, Blast_Score=225, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR007780 [H]

Pfam domain/function: PF05088 Bac_GDH [H]

EC number: =1.4.1.2 [H]

Molecular weight: Translated: 77529; Mature: 77398

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEDATLTNAFIAFCHSNLAHNQPDRFGLDDVRGAFLAHPEIALQLAKLFRARFDPAVE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
GRAELYERVLAETRREVADYNTGHRYLDEVRRTIFHCCLTFITRTLKTNFFVLEKQALAF
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHEE
RLDPAYLTELGTDFTADLPPAMPFRVTFFFSRFGFGYHIGFSDIARGGWRTVICRTPDDL
ECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECHHHHCCCCCEEEEEECCHHH
VTNANTLFRENFVLAHTQHLKNKDIYEGGSKLVVALDASDLKAKDRPLETWRLYKLQYGI
HHCCHHHHHCCCCEEHHHHCCCCCHHCCCCEEEEEECCCCCCCCCCCCCHHEEEEEEECC
TGAFLDIFTTDNGVARHPAVVDYYREDEPIELGPDENMHDNMIETIAWMSKRRGYMLGIG
CEEEEEEEECCCCCCCCCCCEECCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCEEEEEE
IMSSKRVGINHKEYGVTSTGVVAFAEITMAELGIDIRRDPFTVKFTGGPNGDVAGNALRI
EECCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCHHHHHH
MLERCPKVKIGLILDGTAALCDPEGADHGELGRILLKEDLDAFDPAALHPGGFMLFRTGS
HHHHCCCEEEEEEECCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
RREGLRELFRRVIKTDAGLVEEWISLDEFSKEFGELIFSVPADLFIPAGGRPETIDKDNW
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCC
DQFLLPDGTPSARAIVEGANSFITPPARVELQKKGIIVMRDASANKCGVISSSYEIIANL
CCEECCCCCCCHHHHHHCCCCCCCCCHHEEEECCCEEEEECCCCCCCCCCCCHHHHHHHH
LLTEKEFMEHKERYVADVLRILEKRAGDEARLILKRRREQPGTLCTEISDSLSTEINANY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCH
ARLFRFFQARPELCLQPLYRRAILAHLPKIIAEEARFRRRLTQLPQKYLSAILAAEIGSS
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MVYRGDRETEFEDMIKLHLMRSFSAI
HEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGEDATLTNAFIAFCHSNLAHNQPDRFGLDDVRGAFLAHPEIALQLAKLFRARFDPAVE
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
GRAELYERVLAETRREVADYNTGHRYLDEVRRTIFHCCLTFITRTLKTNFFVLEKQALAF
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHEE
RLDPAYLTELGTDFTADLPPAMPFRVTFFFSRFGFGYHIGFSDIARGGWRTVICRTPDDL
ECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECHHHHCCCCCEEEEEECCHHH
VTNANTLFRENFVLAHTQHLKNKDIYEGGSKLVVALDASDLKAKDRPLETWRLYKLQYGI
HHCCHHHHHCCCCEEHHHHCCCCCHHCCCCEEEEEECCCCCCCCCCCCCHHEEEEEEECC
TGAFLDIFTTDNGVARHPAVVDYYREDEPIELGPDENMHDNMIETIAWMSKRRGYMLGIG
CEEEEEEEECCCCCCCCCCCEECCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCEEEEEE
IMSSKRVGINHKEYGVTSTGVVAFAEITMAELGIDIRRDPFTVKFTGGPNGDVAGNALRI
EECCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCHHHHHH
MLERCPKVKIGLILDGTAALCDPEGADHGELGRILLKEDLDAFDPAALHPGGFMLFRTGS
HHHHCCCEEEEEEECCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
RREGLRELFRRVIKTDAGLVEEWISLDEFSKEFGELIFSVPADLFIPAGGRPETIDKDNW
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCC
DQFLLPDGTPSARAIVEGANSFITPPARVELQKKGIIVMRDASANKCGVISSSYEIIANL
CCEECCCCCCCHHHHHHCCCCCCCCCHHEEEECCCEEEEECCCCCCCCCCCCHHHHHHHH
LLTEKEFMEHKERYVADVLRILEKRAGDEARLILKRRREQPGTLCTEISDSLSTEINANY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCH
ARLFRFFQARPELCLQPLYRRAILAHLPKIIAEEARFRRRLTQLPQKYLSAILAAEIGSS
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
MVYRGDRETEFEDMIKLHLMRSFSAI
HEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11133942; 10984043; 9286980 [H]