| Definition | Bacillus anthracis str. Ames, complete genome. |
|---|---|
| Accession | NC_003997 |
| Length | 5,227,293 |
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The map label for this gene is ctpB [H]
Identifier: 30265208
GI number: 30265208
Start: 4902940
End: 4904349
Strand: Reverse
Name: ctpB [H]
Synonym: BA_5414
Alternate gene names: 30265208
Gene position: 4904349-4902940 (Counterclockwise)
Preceding gene: 30265209
Following gene: 30265207
Centisome position: 93.82
GC content: 37.87
Gene sequence:
>1410_bases ATGGTTGTTGCATTTTTAATTGGTGCTGGCGGAATGTTTGCAGGTATGTCTTTATTTGGGGTTAATCCAGCAGAAGTAAC GCAAACAATTTCGAGTGGAAACGCTAGCACTGCGCAAGGGAATTTGGCAAAAATTAATGAGGCGTATGCACTAATTGATT CACGTTATGTGGAAGACGTGAAAGATGAAAAATTAGTCGAAGGTGCAATACAAGGCATGTTGTCTACGCTGAAGGACCCT TATTCCACGTATATGGATAAAGAAACGGCTAAACAGTTTAGTGAATCGCTTGATCCTGAGTTAGAAGGGATCGGGGCTGA GGTGAACAAAACGGACGGTAAGCTTATTATCGTATCTCCAATTAAAGGCTCACCGGCAGAAAAGATTGGAATTAAACCGA ATGACCAAATTTTATCTGTAGATGGAAATAGTGTGAAAGATTTATCACGTGAAGAAGCAGTATTAAAGATTCGTGGTAAA AAAGGAACGACTGTTGCGATTGAAATTAAGCGTGCAGGAGTAGCTGATCCGATTGTATTTAAAATTAAGCGTGAAAAAAT TCCAATCTTCACAGTGTTTAGCTCTGTGAAACAAGAGAGTGGAAAAGATATCGGTTATATGCAAATCACTTCTTTTGCTG AAAATACAGCGAAAGAATTTAAGGATCAGTTAAAAGAGTTAGAGAAGAAAAACATAAAAGGGCTAGTTATTGACGTGCGC GGTAATCCTGGTGGCTACTTAAATAGTGTAGAAGAGATACTAGGGGAAATTATGACGGATAAAAAGCCGATGCTACAAGT AGAGCAAAGAAATGGTGAGAAGAAGAAATTCTCTACGGAACTGAAAGAGAGAAAGCCATATCCAATTTCAGTATTAATTG ATAACGGAAGTGCTTCTGCTTCAGAGATTTTAGCGGGTGCGCTAAAAGAGGGAGAAGGATACGATTTAATTGGTGAAAAA ACGTTTGGTAAAGGTACTGTTCAGCAAGCTGTTCCATTTAAAGATGGCAGCAATATCAAATTAACGATGTTCAAATGGTT AACACCGGATGGAAACTGGATTCATAAAAAAGGAATCAAGCCAACTGTAGAAGTGAAACAACCAGATTATTATCATGCGA CACCAATTCAAATTGAAAAGACACTTTCATACAATGCAAATGATGTACAAGTAAAACACGCACAAGAAATGCTTAAGAGT TTAGGATATGTACCAGGACGTGAAGATGGATACTTTAGTAAAGAGACAGAATCAGCACTGAAAGCATTCCAAAATGCGAA TAAGATGGAAGCGACAGGGCAGCTAGATAAAAAGACAGCTGAGGCGATTCAAACGAAAATTATTGAAAAAATCCGTTCTG GAGAAAATGATCTCCAATTACAGTCAGCATTAAAATTAATGGCGAAATAA
Upstream 100 bases:
>100_bases AGGTAAAGGCATCACACGCTGTGTGATGCCTTTTGCTACACCACCTGTGTGTTTTGGAAAGGGGAATTCCGCATTGAAAC GTAGAGTTGCAATTATTGGA
Downstream 100 bases:
>100_bases AAAGAAATACAGGCAGTTTGCTGCCTGTATTTTTTTGTGTTAAACAAACGCTTGTCCAGTTATGATAATATAAAAAGAAA GAATGATATAAATGGTGGTG
Product: carboxyl-terminal protease
Products: NA
Alternate protein names: C-terminal processing protease [H]
Number of amino acids: Translated: 469; Mature: 469
Protein sequence:
>469_residues MVVAFLIGAGGMFAGMSLFGVNPAEVTQTISSGNASTAQGNLAKINEAYALIDSRYVEDVKDEKLVEGAIQGMLSTLKDP YSTYMDKETAKQFSESLDPELEGIGAEVNKTDGKLIIVSPIKGSPAEKIGIKPNDQILSVDGNSVKDLSREEAVLKIRGK KGTTVAIEIKRAGVADPIVFKIKREKIPIFTVFSSVKQESGKDIGYMQITSFAENTAKEFKDQLKELEKKNIKGLVIDVR GNPGGYLNSVEEILGEIMTDKKPMLQVEQRNGEKKKFSTELKERKPYPISVLIDNGSASASEILAGALKEGEGYDLIGEK TFGKGTVQQAVPFKDGSNIKLTMFKWLTPDGNWIHKKGIKPTVEVKQPDYYHATPIQIEKTLSYNANDVQVKHAQEMLKS LGYVPGREDGYFSKETESALKAFQNANKMEATGQLDKKTAEAIQTKIIEKIRSGENDLQLQSALKLMAK
Sequences:
>Translated_469_residues MVVAFLIGAGGMFAGMSLFGVNPAEVTQTISSGNASTAQGNLAKINEAYALIDSRYVEDVKDEKLVEGAIQGMLSTLKDP YSTYMDKETAKQFSESLDPELEGIGAEVNKTDGKLIIVSPIKGSPAEKIGIKPNDQILSVDGNSVKDLSREEAVLKIRGK KGTTVAIEIKRAGVADPIVFKIKREKIPIFTVFSSVKQESGKDIGYMQITSFAENTAKEFKDQLKELEKKNIKGLVIDVR GNPGGYLNSVEEILGEIMTDKKPMLQVEQRNGEKKKFSTELKERKPYPISVLIDNGSASASEILAGALKEGEGYDLIGEK TFGKGTVQQAVPFKDGSNIKLTMFKWLTPDGNWIHKKGIKPTVEVKQPDYYHATPIQIEKTLSYNANDVQVKHAQEMLKS LGYVPGREDGYFSKETESALKAFQNANKMEATGQLDKKTAEAIQTKIIEKIRSGENDLQLQSALKLMAK >Mature_469_residues MVVAFLIGAGGMFAGMSLFGVNPAEVTQTISSGNASTAQGNLAKINEAYALIDSRYVEDVKDEKLVEGAIQGMLSTLKDP YSTYMDKETAKQFSESLDPELEGIGAEVNKTDGKLIIVSPIKGSPAEKIGIKPNDQILSVDGNSVKDLSREEAVLKIRGK KGTTVAIEIKRAGVADPIVFKIKREKIPIFTVFSSVKQESGKDIGYMQITSFAENTAKEFKDQLKELEKKNIKGLVIDVR GNPGGYLNSVEEILGEIMTDKKPMLQVEQRNGEKKKFSTELKERKPYPISVLIDNGSASASEILAGALKEGEGYDLIGEK TFGKGTVQQAVPFKDGSNIKLTMFKWLTPDGNWIHKKGIKPTVEVKQPDYYHATPIQIEKTLSYNANDVQVKHAQEMLKS LGYVPGREDGYFSKETESALKAFQNANKMEATGQLDKKTAEAIQTKIIEKIRSGENDLQLQSALKLMAK
Specific function: Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the regulatory protein
COG id: COG0793
COG function: function code M; Periplasmic protease
Gene ontology:
Cell location: Forespore intermembrane space. Note=Is expressed in both the mother cell and forespore compartments but that synthesis in the forespore is both necessary and sufficient for the proper timing of pro-sigma-K processing [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PDZ (DHR) domain [H]
Homologues:
Organism=Escherichia coli, GI1788134, Length=308, Percent_Identity=31.8181818181818, Blast_Score=117, Evalue=2e-27,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001478 - InterPro: IPR005151 - InterPro: IPR004447 - InterPro: IPR002477 [H]
Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]
EC number: =3.4.21.102 [H]
Molecular weight: Translated: 51412; Mature: 51412
Theoretical pI: Translated: 8.49; Mature: 8.49
Prosite motif: PS50106 PDZ
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVVAFLIGAGGMFAGMSLFGVNPAEVTQTISSGNASTAQGNLAKINEAYALIDSRYVEDV CEEEEEECCCCHHHCCCEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH KDEKLVEGAIQGMLSTLKDPYSTYMDKETAKQFSESLDPELEGIGAEVNKTDGKLIIVSP HHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEEEEC IKGSPAEKIGIKPNDQILSVDGNSVKDLSREEAVLKIRGKKGTTVAIEIKRAGVADPIVF CCCCCHHCCCCCCCCCEEEECCCCHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCCEEE KIKREKIPIFTVFSSVKQESGKDIGYMQITSFAENTAKEFKDQLKELEKKNIKGLVIDVR EEECCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE GNPGGYLNSVEEILGEIMTDKKPMLQVEQRNGEKKKFSTELKERKPYPISVLIDNGSASA CCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCH SEILAGALKEGEGYDLIGEKTFGKGTVQQAVPFKDGSNIKLTMFKWLTPDGNWIHKKGIK HHHHHHHHCCCCCCEECCCCCCCCCCHHHCCCCCCCCCEEEEEEEEECCCCCEEECCCCC PTVEVKQPDYYHATPIQIEKTLSYNANDVQVKHAQEMLKSLGYVPGREDGYFSKETESAL CEEEECCCCCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH KAFQNANKMEATGQLDKKTAEAIQTKIIEKIRSGENDLQLQSALKLMAK HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC >Mature Secondary Structure MVVAFLIGAGGMFAGMSLFGVNPAEVTQTISSGNASTAQGNLAKINEAYALIDSRYVEDV CEEEEEECCCCHHHCCCEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH KDEKLVEGAIQGMLSTLKDPYSTYMDKETAKQFSESLDPELEGIGAEVNKTDGKLIIVSP HHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEEEEC IKGSPAEKIGIKPNDQILSVDGNSVKDLSREEAVLKIRGKKGTTVAIEIKRAGVADPIVF CCCCCHHCCCCCCCCCEEEECCCCHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCCEEE KIKREKIPIFTVFSSVKQESGKDIGYMQITSFAENTAKEFKDQLKELEKKNIKGLVIDVR EEECCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE GNPGGYLNSVEEILGEIMTDKKPMLQVEQRNGEKKKFSTELKERKPYPISVLIDNGSASA CCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCH SEILAGALKEGEGYDLIGEKTFGKGTVQQAVPFKDGSNIKLTMFKWLTPDGNWIHKKGIK HHHHHHHHCCCCCCEECCCCCCCCCCHHHCCCCCCCCCEEEEEEEEECCCCCEEECCCCC PTVEVKQPDYYHATPIQIEKTLSYNANDVQVKHAQEMLKSLGYVPGREDGYFSKETESAL CEEEECCCCCCCCCCEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH KAFQNANKMEATGQLDKKTAEAIQTKIIEKIRSGENDLQLQSALKLMAK HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9570401; 9384377 [H]