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The map label for this gene is infC [H]

Identifier: 30264645

GI number: 30264645

Start: 4380635

End: 4381195

Strand: Reverse

Name: infC [H]

Synonym: BA_4819

Alternate gene names: 30264645

Gene position: 4381195-4380635 (Counterclockwise)

Preceding gene: 30264646

Following gene: 30264644

Centisome position: 83.81

GC content: 38.32

Gene sequence:

>561_bases
ATGACTACAAACTATGTTCTGAGAAAACCTTGGAGGTGGCTTACTATTAGCAAGGATATGATGATTAACGAGCAAATTCG
TGCACGTGAAGTACGTTTAGTTGGCGCAAATGGCGATCAACTTGGAATCAAGTCTCGTAATGACGCTTTAGACTTAGCTG
CAAATCTTAATCTTGATTTAGTATTAGTTGCTCCAAATGCGAAACCGCCAGTATGCCGCATTATGGACTACGGTAAATTC
CGCTTTGAGCAACAGAAGAAAGAAAAAGAACAGCGCAAAAATCAAAAAGTAATTAGCATGAAAGAAGTTCGTTTAAGTCC
AACAATTGATGAACACGACTTTAACACAAAACTTCGTAATGCTATCAAGTTTTTAGAGAAAGGCGACAAGGTTAAAGCGT
CAATTCGCTTTAAAGGACGTGCCATTACTCATAAAGAAATCGGTCAACGTGTTTTAGATCGCTTCTCAGAAGCTTGTGCT
GAAGTTAGTACAATCGAATCTAAGCCTAAAATGGAAGGACGCAGTATGTTCTTAGTTTTAGCACCGAAAAACGATAAGTA
A

Upstream 100 bases:

>100_bases
CACCTGATGGACGCATTCGCAGTTTACAGGTAAATGTATTTCTTACTTAAGATTTTACAAGTGTGGGTGTCGTATGCCCG
CACTTTTTTTGTCGGGTTCT

Downstream 100 bases:

>100_bases
TAGATAGAGGAGGAAATACCTATGCCTAAACAAAAAACTCATCGCGGCGCTGCAAAGCGTTTCAAAAAGACTGGATCAGG
TAAACTGAAACGTTCTCACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKF
RFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACA
EVSTIESKPKMEGRSMFLVLAPKNDK

Sequences:

>Translated_186_residues
MTTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKF
RFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACA
EVSTIESKPKMEGRSMFLVLAPKNDK
>Mature_185_residues
TTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFR
FEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAE
VSTIESKPKMEGRSMFLVLAPKNDK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=53.9877300613497, Blast_Score=166, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21471; Mature: 21340

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDL
CCCCCEEECCEEEEEECCCHHCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCEEE
VLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRN
EEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEHEEEEECCCCCCCCCHHHHHH
AIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVL
HHHHHHCCCEEEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
APKNDK
ECCCCC
>Mature Secondary Structure 
TTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDL
CCCCEEECCEEEEEECCCHHCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCEEE
VLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRN
EEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEHEEEEECCCCCCCCCHHHHHH
AIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVL
HHHHHHCCCEEEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
APKNDK
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]