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The map label for this gene is nsr [H]

Identifier: 30263413

GI number: 30263413

Start: 3223133

End: 3223825

Strand: Reverse

Name: nsr [H]

Synonym: BA_3510

Alternate gene names: 30263413

Gene position: 3223825-3223133 (Counterclockwise)

Preceding gene: 30263417

Following gene: 30263412

Centisome position: 61.67

GC content: 31.17

Gene sequence:

>693_bases
ATGAAGAAAGTATGTAATTCTATTAAATTAGCAGAGTATATGAAACAAAATAATATTGACTCCTTTTTTAGTAATGATAT
GAATCCGTATATGGAACTTATATTTTTTAAAAAGAATGAGTTTATTTGTAGAGAAAATGAAGAGATAGACTATTTATATT
TTTTCGTTGAAGGAAAAGCGAAGGCATTTAATACATTAAGTAACGGTAAATCTGTATTATTATGCTTTTATGATAGTTTG
CAGCTGTTAGGAGATGTGGAGTTAATTCATTCGCAAAAGACAGCTTCAAACGTACAAGTAATGGCAGATTCATATTGTGT
TGGTTTGCCTTTAGGAAAAGTGAGAAATCAACTATTTCATGATGCAAAATTTTTACGATGTATTTGCGGATCATTAGCAC
ATAAGTTAAATCGACTTTCCAAAAATAGTACAATTAATTTATTGTATCCGCTTGAAAATAGACTTGCGAGTTACATGTTA
GCAGCAGGAGAACGGGCAGTACAGCACGGAAATAGAATTGTATTTAGTGGGAATTTAACGGAAACAGCGGAATTGTTAGG
AACGAGTTATCGACACTTATTACGAACGTTGAATATCTTTTGTGATAAAGAGATTATAAAGAAAAACAATGGTTGCTTTG
AAGTAGTGAATGTGGATGTTTTGAGAGAATTGGCAGCAGATGTTTATAAATAG

Upstream 100 bases:

>100_bases
GACTGTATCATGCTGAAATTGTGTATTACTATGACATATGTCATAGTGGAAGAAGAAAATTTTGATTACAATGGGGATGA
GTTGTAAAGGTGGGGGAACG

Downstream 100 bases:

>100_bases
GAGGAGAGTATAAATGATAACACCTATATTTAGAATTTTTGATATTGAAAAAGCAAAGCTATTTTACGTAGGTTTTTTAG
GATTTAAACTGGATTGGGAA

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKKVCNSIKLAEYMKQNNIDSFFSNDMNPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQKTASNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHGNRIVFSGNLTETAELLGTSYRHLLRTLNIFCDKEIIKKNNGCFEVVNVDVLRELAADVYK

Sequences:

>Translated_230_residues
MKKVCNSIKLAEYMKQNNIDSFFSNDMNPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQKTASNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHGNRIVFSGNLTETAELLGTSYRHLLRTLNIFCDKEIIKKNNGCFEVVNVDVLRELAADVYK
>Mature_230_residues
MKKVCNSIKLAEYMKQNNIDSFFSNDMNPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQKTASNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHGNRIVFSGNLTETAELLGTSYRHLLRTLNIFCDKEIIKKNNGCFEVVNVDVLRELAADVYK

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=215, Percent_Identity=30.2325581395349, Blast_Score=111, Evalue=4e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 26298; Mature: 26298

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVCNSIKLAEYMKQNNIDSFFSNDMNPYMELIFFKKNEFICRENEEIDYLYFFVEGKA
CCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHEEEEECCCEEECCCCCCEEEEEEEECCH
KAFNTLSNGKSVLLCFYDSLQLLGDVELIHSQKTASNVQVMADSYCVGLPLGKVRNQLFH
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCEEEECCEEECCCHHHHHHHHHH
DAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYMLAAGERAVQHGNRIVFSGNLT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
ETAELLGTSYRHLLRTLNIFCDKEIIKKNNGCFEVVNVDVLRELAADVYK
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKVCNSIKLAEYMKQNNIDSFFSNDMNPYMELIFFKKNEFICRENEEIDYLYFFVEGKA
CCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHEEEEECCCEEECCCCCCEEEEEEEECCH
KAFNTLSNGKSVLLCFYDSLQLLGDVELIHSQKTASNVQVMADSYCVGLPLGKVRNQLFH
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCEEEECCEEECCCHHHHHHHHHH
DAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYMLAAGERAVQHGNRIVFSGNLT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
ETAELLGTSYRHLLRTLNIFCDKEIIKKNNGCFEVVNVDVLRELAADVYK
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]