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The map label for this gene is fes [H]

Identifier: 30262674

GI number: 30262674

Start: 2509637

End: 2510785

Strand: Reverse

Name: fes [H]

Synonym: BA_2694

Alternate gene names: 30262674

Gene position: 2510785-2509637 (Counterclockwise)

Preceding gene: 30262675

Following gene: 30262673

Centisome position: 48.03

GC content: 31.51

Gene sequence:

>1149_bases
ATGAGAAAACTACATATAGAATACTACAAAGGAGGAAGAGAGGTGACTACAATAATCAGTCCTAAATTAGAGAAGCTTAA
AAATCACTTAAAGAACGGAAATGAAAAAGCTCTTTATACTTTTTTGCATGAAATCAAGTCAAATCATACACCACTAGTAG
AACAATGTCCTATAGATAATCAGTATAAACTTATAACGTATATATGGTTAGGTGATCAAAATACTGAAAATGTTTATGTA
GTCGGTAGTTTTCCTGGTTGGGATCTGTCTGTAAATCAATTACAACGATTATTACAGACAAATATTTGGTATGTTACGTT
TAGGACGAATAAGAGGTTTATTTCAACTTATTATTTTACAGTAAATGATTTTTTCAAAAATGATTGGATAAAGCGTAGTG
AACAGTACCGACTAGACCCATTCAATGAAAATGTATTTGGAGAAGGTGCCAATAAAGCGTCTGTGTTAAAAATAGATATG
GACGTGCAGTATAGCAGTCGTTTTCCTTCAAATCATTATCCATCTGGAAAGATTGAAACATATTCTTTTTATAGTTCGAT
TTTAAATAACACACGTAAACTTCATATTTATACGCCTCATGATTATTCTCACACTTCACATCTTCAAGAACTTCTCATTG
TATTTGATGGGAATTCATTCATTAATGACCTTTCAATCACAAAAACACTTAATTATTTAATTTACGAAAAAGAAATCCCA
TCTTGTATTGCTGTTGCTATAGATCCTGTTGATCGATTAGAAGAGCTAACTTATAACGATAAAATGAATACATTTTTAAT
GAAGGAATTACTTCCATGGATTCAAACTAAATATCATGTGTATCAAAAAGCAAAACATACAACAATTGCTGGTTTCAGCC
TTGGTGGCTTAGCCGCTTTTTATGTAGCACTTCAAAATCCACATATTTTCGGAAATGTGTTGTCAATGTCTGGATCCGTA
CATTGGAAAAAGGATGATTATGAAAATACAATTCCTTGGATTGAAAATCAAATTTCATCAATAGATTCTAATGCGACTCA
TCTCAATTCTTACATAGCAGTAGGTGAACTTGAAAACGAATCTCTTTTAAAGGCTAATAGACGGCTACATAAAGCTTTAG
AAGAAAAGAAATACCCAAACCACTTATGA

Upstream 100 bases:

>100_bases
ATAAAATCATTGGAACTTTCTATTCAAGCAATTGATCATTTTTCTAATCAATAACTTCTCTAAACACATAACTTACGACT
ACTTTTATATAGGGATTCTA

Downstream 100 bases:

>100_bases
AGAGTTTCAAGGCGGACATGATAGCGTGTGGTGGCGAGAAAAGCTATTCGATGGATTAAGGGCATTAGAACTTACAAAAA
CGACACTAAAAAATAAAAAG

Product: esterase, putative

Products: Fe [C]

Alternate protein names: Ferric enterobactin esterase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MRKLHIEYYKGGREVTTIISPKLEKLKNHLKNGNEKALYTFLHEIKSNHTPLVEQCPIDNQYKLITYIWLGDQNTENVYV
VGSFPGWDLSVNQLQRLLQTNIWYVTFRTNKRFISTYYFTVNDFFKNDWIKRSEQYRLDPFNENVFGEGANKASVLKIDM
DVQYSSRFPSNHYPSGKIETYSFYSSILNNTRKLHIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIP
SCIAVAIDPVDRLEELTYNDKMNTFLMKELLPWIQTKYHVYQKAKHTTIAGFSLGGLAAFYVALQNPHIFGNVLSMSGSV
HWKKDDYENTIPWIENQISSIDSNATHLNSYIAVGELENESLLKANRRLHKALEEKKYPNHL

Sequences:

>Translated_382_residues
MRKLHIEYYKGGREVTTIISPKLEKLKNHLKNGNEKALYTFLHEIKSNHTPLVEQCPIDNQYKLITYIWLGDQNTENVYV
VGSFPGWDLSVNQLQRLLQTNIWYVTFRTNKRFISTYYFTVNDFFKNDWIKRSEQYRLDPFNENVFGEGANKASVLKIDM
DVQYSSRFPSNHYPSGKIETYSFYSSILNNTRKLHIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIP
SCIAVAIDPVDRLEELTYNDKMNTFLMKELLPWIQTKYHVYQKAKHTTIAGFSLGGLAAFYVALQNPHIFGNVLSMSGSV
HWKKDDYENTIPWIENQISSIDSNATHLNSYIAVGELENESLLKANRRLHKALEEKKYPNHL
>Mature_382_residues
MRKLHIEYYKGGREVTTIISPKLEKLKNHLKNGNEKALYTFLHEIKSNHTPLVEQCPIDNQYKLITYIWLGDQNTENVYV
VGSFPGWDLSVNQLQRLLQTNIWYVTFRTNKRFISTYYFTVNDFFKNDWIKRSEQYRLDPFNENVFGEGANKASVLKIDM
DVQYSSRFPSNHYPSGKIETYSFYSSILNNTRKLHIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIP
SCIAVAIDPVDRLEELTYNDKMNTFLMKELLPWIQTKYHVYQKAKHTTIAGFSLGGLAAFYVALQNPHIFGNVLSMSGSV
HWKKDDYENTIPWIENQISSIDSNATHLNSYIAVGELENESLLKANRRLHKALEEKKYPNHL

Specific function: Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use [H]

COG id: COG2382

COG function: function code P; Enterochelin esterase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fes family [H]

Homologues:

Organism=Escherichia coli, GI1786799, Length=345, Percent_Identity=24.6376811594203, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021764
- InterPro:   IPR000801
- InterPro:   IPR014756 [H]

Pfam domain/function: PF11806 DUF3327; PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 44634; Mature: 44634

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLHIEYYKGGREVTTIISPKLEKLKNHLKNGNEKALYTFLHEIKSNHTPLVEQCPIDN
CCEEEEEEECCCCEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHCCCCC
QYKLITYIWLGDQNTENVYVVGSFPGWDLSVNQLQRLLQTNIWYVTFRTNKRFISTYYFT
CEEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECCCEEEEEEEEE
VNDFFKNDWIKRSEQYRLDPFNENVFGEGANKASVLKIDMDVQYSSRFPSNHYPSGKIET
EHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECEEECCCCCCCCCCCCCEEH
YSFYSSILNNTRKLHIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIP
HHHHHHHHCCCEEEEEECCCCCCHHHHHHEEEEEECCCCHHCHHHHHHHHHHEEECCCCC
SCIAVAIDPVDRLEELTYNDKMNTFLMKELLPWIQTKYHVYQKAKHTTIAGFSLGGLAAF
CEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHH
YVALQNPHIFGNVLSMSGSVHWKKDDYENTIPWIENQISSIDSNATHLNSYIAVGELENE
HHHCCCCCEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHCEEEEECCCCH
SLLKANRRLHKALEEKKYPNHL
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKLHIEYYKGGREVTTIISPKLEKLKNHLKNGNEKALYTFLHEIKSNHTPLVEQCPIDN
CCEEEEEEECCCCEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHCCCCC
QYKLITYIWLGDQNTENVYVVGSFPGWDLSVNQLQRLLQTNIWYVTFRTNKRFISTYYFT
CEEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECCCEEEEEEEEE
VNDFFKNDWIKRSEQYRLDPFNENVFGEGANKASVLKIDMDVQYSSRFPSNHYPSGKIET
EHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECEEECCCCCCCCCCCCCEEH
YSFYSSILNNTRKLHIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIP
HHHHHHHHCCCEEEEEECCCCCCHHHHHHEEEEEECCCCHHCHHHHHHHHHHEEECCCCC
SCIAVAIDPVDRLEELTYNDKMNTFLMKELLPWIQTKYHVYQKAKHTTIAGFSLGGLAAF
CEEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHH
YVALQNPHIFGNVLSMSGSVHWKKDDYENTIPWIENQISSIDSNATHLNSYIAVGELENE
HHHCCCCCEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHCEEEEECCCCH
SLLKANRRLHKALEEKKYPNHL
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrienterobactin [C]

Specific reaction: ferrienterobactin = Fe [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2974033; 9278503; 8905232 [H]