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The map label for this gene is yvcN [H]

Identifier: 30262173

GI number: 30262173

Start: 2008356

End: 2009195

Strand: Reverse

Name: yvcN [H]

Synonym: BA_2152

Alternate gene names: 30262173

Gene position: 2009195-2008356 (Counterclockwise)

Preceding gene: 30262176

Following gene: 30262170

Centisome position: 38.44

GC content: 31.31

Gene sequence:

>840_bases
ATGATGACCAATTTACAAAAGGAGTTTTTTAAACGACTAAAAATTCCTGCAAAAGAAATAACATTTAATGATTTAGATGA
AATTCTCTTAAACATGGGAATGATTCTCCCCTATGAAAATCTTGATATTATGGCTGGCACTATTAAAAACATCTCAAAAA
ATAACTTAGTAGAAAAGTTACTTATTCAAAAACGAGGCGGTCTTTGTTATGAATTAAACTCCTTACTATATTACTTTTTA
ATGGATTGTGGATTTCAAGTATATAAAGTAGCCGGTACTGTTTATGACCTTTACGATAATAAATGGAAACCTGATGATGG
TCATGTCATTATCATATTACATCATAATAAAAAAGATTATGTTATAGATGCCGGTTTTGCCTCTCACCTACCTTTACATC
CAGTCCCTTTTAGCGGAGAAGTCATATCTTCTCAAACGGGTGAATATCGAATTCGCAAACGAACTACTCAAAAAGGTACA
CACATTTTAGAAATGAGAAAAGGAGCTAACGGGGAATCTACAAATTTTTTACAATCTGAACCTTCAGATGAATGGAAAAT
AGGCTATGCCTTCACTTTAGATCCAATAGATGAGCAAAAGGTGAATAACATTCAAAAAGTCATTGTAGAACATAAAGAAT
CTCCTTTTAATAAAGGAGCTATCACTTGTAAATTAACTAATTATGGTCACATATCATTAACAAATAAAAATTATACAGAA
ACCTTTAAAGGCACCAAAAATAAACGTCCAATAGAATCAAAAGATTATGCTCGCATTCTTCGTGAATCTTTTGGAATAAC
ACAAGTGAAATATGTAGGAAAAACACTAGAAAGAGGTTAG

Upstream 100 bases:

>100_bases
ATATATTATGATAATTTTCGCAGACTTGAATTAAACTTTCAGAAGTACTAACCTATCGGTGAGCAGAAGATAATTCTGTA
AAAAGAAAGGAGAATGCTTT

Downstream 100 bases:

>100_bases
TTGACTAAAAGTATTTCATAATAAAGCAGATTCCATATTTAGAATCTGCTTTATTTTATATTTTGTTATAAAGAAATTTG
TTTTGCTCTTATCCTTTAAT

Product: N-acetyltransferase family protein

Products: CoA; an n-acetoxyarylamine [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MMTNLQKEFFKRLKIPAKEITFNDLDEILLNMGMILPYENLDIMAGTIKNISKNNLVEKLLIQKRGGLCYELNSLLYYFL
MDCGFQVYKVAGTVYDLYDNKWKPDDGHVIIILHHNKKDYVIDAGFASHLPLHPVPFSGEVISSQTGEYRIRKRTTQKGT
HILEMRKGANGESTNFLQSEPSDEWKIGYAFTLDPIDEQKVNNIQKVIVEHKESPFNKGAITCKLTNYGHISLTNKNYTE
TFKGTKNKRPIESKDYARILRESFGITQVKYVGKTLERG

Sequences:

>Translated_279_residues
MMTNLQKEFFKRLKIPAKEITFNDLDEILLNMGMILPYENLDIMAGTIKNISKNNLVEKLLIQKRGGLCYELNSLLYYFL
MDCGFQVYKVAGTVYDLYDNKWKPDDGHVIIILHHNKKDYVIDAGFASHLPLHPVPFSGEVISSQTGEYRIRKRTTQKGT
HILEMRKGANGESTNFLQSEPSDEWKIGYAFTLDPIDEQKVNNIQKVIVEHKESPFNKGAITCKLTNYGHISLTNKNYTE
TFKGTKNKRPIESKDYARILRESFGITQVKYVGKTLERG
>Mature_279_residues
MMTNLQKEFFKRLKIPAKEITFNDLDEILLNMGMILPYENLDIMAGTIKNISKNNLVEKLLIQKRGGLCYELNSLLYYFL
MDCGFQVYKVAGTVYDLYDNKWKPDDGHVIIILHHNKKDYVIDAGFASHLPLHPVPFSGEVISSQTGEYRIRKRTTQKGT
HILEMRKGANGESTNFLQSEPSDEWKIGYAFTLDPIDEQKVNNIQKVIVEHKESPFNKGAITCKLTNYGHISLTNKNYTE
TFKGTKNKRPIESKDYARILRESFGITQVKYVGKTLERG

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI237649128, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI237649126, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI237649124, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI237649122, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI237649119, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI42741671, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI237649009, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI237649132, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI237649130, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787736, Length=273, Percent_Identity=23.4432234432234, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: 2.3.1.118 [C]

Molecular weight: Translated: 32081; Mature: 32081

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTNLQKEFFKRLKIPAKEITFNDLDEILLNMGMILPYENLDIMAGTIKNISKNNLVEKL
CCCCHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCCCCCCCCCEEHHHHHHCCHHHHHHHH
LIQKRGGLCYELNSLLYYFLMDCGFQVYKVAGTVYDLYDNKWKPDDGHVIIILHHNKKDY
HHHHCCCCEEHHHHHHHHHHHHCCCEEEHHHHHHEECCCCCCCCCCCEEEEEEEECCCCE
VIDAGFASHLPLHPVPFSGEVISSQTGEYRIRKRTTQKGTHILEMRKGANGESTNFLQSE
EEECCCCCCCCCCCCCCCCCEECCCCCCEEEEHHHHHCCCEEEEECCCCCCCCCCCCCCC
PSDEWKIGYAFTLDPIDEQKVNNIQKVIVEHKESPFNKGAITCKLTNYGHISLTNKNYTE
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEECCCCCHH
TFKGTKNKRPIESKDYARILRESFGITQVKYVGKTLERG
HHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MMTNLQKEFFKRLKIPAKEITFNDLDEILLNMGMILPYENLDIMAGTIKNISKNNLVEKL
CCCCHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCCCCCCCCCEEHHHHHHCCHHHHHHHH
LIQKRGGLCYELNSLLYYFLMDCGFQVYKVAGTVYDLYDNKWKPDDGHVIIILHHNKKDY
HHHHCCCCEEHHHHHHHHHHHHCCCEEEHHHHHHEECCCCCCCCCCCEEEEEEEECCCCE
VIDAGFASHLPLHPVPFSGEVISSQTGEYRIRKRTTQKGTHILEMRKGANGESTNFLQSE
EEECCCCCCCCCCCCCCCCCEECCCCCCEEEEHHHHHCCCEEEEECCCCCCCCCCCCCCC
PSDEWKIGYAFTLDPIDEQKVNNIQKVIVEHKESPFNKGAITCKLTNYGHISLTNKNYTE
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEECCCCCHH
TFKGTKNKRPIESKDYARILRESFGITQVKYVGKTLERG
HHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; an n-hydroxyarylamine [C]

Specific reaction: Acetyl-CoA + an n-hydroxyarylamine = CoA + an n-acetoxyarylamine [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]