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The map label for this gene is fnr [H]

Identifier: 30262153

GI number: 30262153

Start: 1990688

End: 1991368

Strand: Reverse

Name: fnr [H]

Synonym: BA_2132

Alternate gene names: 30262153

Gene position: 1991368-1990688 (Counterclockwise)

Preceding gene: 30262162

Following gene: 30262145

Centisome position: 38.1

GC content: 31.72

Gene sequence:

>681_bases
ATGACATTATCTCAAGATTTAAAAGAATTACTTGCATCTGTTGAATATAAAATGCAGATAAAAAAAGGTAATTTTATTTT
TCAAGAAGGTATGGAGGCAACCGAACTCTATATCATCCACTCAGGAAAAGTACAAATTAGTAAACTTAGTGCTGACGGAC
AAGAACTAACACTTCGAATTTGTTCGGCATACGACATTATTGGAGAATTAACATTGTTCACGGATAATGCGAAGTATTTA
TTAAATTCAAAATGCCTTGAAGATGTTGAAGTAGGCGTTATAAAGCGTGAAGCGTTAGAAAAAGAATTACTCCAAAAACC
AGCTCTTGTATTTGAATTTATGAAATGGATTAGTGAACATTTAAGAAGAATGCAAACGAAGTTCCGAGATTTAGTATTAC
ACGGCAAAAAAGGTGCCTTATATTCTACTCTCATACGAATGACAAATAGTTATGGTGTTTTAAAAGAAAATGGTATTCTC
ATCGATTTACCGTTAACGAATCAAGAACTTGCTAATTTCTGTGCAACTTCACGTGAAAGTGTAAATCGAATGTTAAATGA
ATTAAAAAAGCAAGGGACAATTTCTATTCATAAAGGAAAGATTACAATCCACGATTTACAATTTTTAAAATGTGAAATTG
CTTGTGAAGATTGTTCTGCTTCTGTTTGTAGTATCGATTAG

Upstream 100 bases:

>100_bases
ACATTATTTTTAAAATAGCTCTTGCATTTTCATCATATTTACACTCAAAATAGGAAATGTATTGCTTATAAGAAGAAAGG
TGATTGCTGTGGCAAACAGT

Downstream 100 bases:

>100_bases
CGTCTTATTTAGATGCTAATCTTTTTTCATATTATGTTCTTTTTTAAACTTAACAGTTAACTCCCCATTGCCATCAAGAT
AAGATGTTGAAATACTCTAA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTLSQDLKELLASVEYKMQIKKGNFIFQEGMEATELYIIHSGKVQISKLSADGQELTLRICSAYDIIGELTLFTDNAKYL
LNSKCLEDVEVGVIKREALEKELLQKPALVFEFMKWISEHLRRMQTKFRDLVLHGKKGALYSTLIRMTNSYGVLKENGIL
IDLPLTNQELANFCATSRESVNRMLNELKKQGTISIHKGKITIHDLQFLKCEIACEDCSASVCSID

Sequences:

>Translated_226_residues
MTLSQDLKELLASVEYKMQIKKGNFIFQEGMEATELYIIHSGKVQISKLSADGQELTLRICSAYDIIGELTLFTDNAKYL
LNSKCLEDVEVGVIKREALEKELLQKPALVFEFMKWISEHLRRMQTKFRDLVLHGKKGALYSTLIRMTNSYGVLKENGIL
IDLPLTNQELANFCATSRESVNRMLNELKKQGTISIHKGKITIHDLQFLKCEIACEDCSASVCSID
>Mature_225_residues
TLSQDLKELLASVEYKMQIKKGNFIFQEGMEATELYIIHSGKVQISKLSADGQELTLRICSAYDIIGELTLFTDNAKYLL
NSKCLEDVEVGVIKREALEKELLQKPALVFEFMKWISEHLRRMQTKFRDLVLHGKKGALYSTLIRMTNSYGVLKENGILI
DLPLTNQELANFCATSRESVNRMLNELKKQGTISIHKGKITIHDLQFLKCEIACEDCSASVCSID

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25657; Mature: 25526

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSQDLKELLASVEYKMQIKKGNFIFQEGMEATELYIIHSGKVQISKLSADGQELTLRI
CCCHHHHHHHHHHHHHEEEEECCCEEECCCCCEEEEEEEECCCEEEEEECCCCHHHHHHH
CSAYDIIGELTLFTDNAKYLLNSKCLEDVEVGVIKREALEKELLQKPALVFEFMKWISEH
HHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LRRMQTKFRDLVLHGKKGALYSTLIRMTNSYGVLKENGILIDLPLTNQELANFCATSRES
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEECCCEEEEECCCHHHHHHHHHCCHHH
VNRMLNELKKQGTISIHKGKITIHDLQFLKCEIACEDCSASVCSID
HHHHHHHHHHCCCEEEEECEEEEEHHEEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TLSQDLKELLASVEYKMQIKKGNFIFQEGMEATELYIIHSGKVQISKLSADGQELTLRI
CCHHHHHHHHHHHHHEEEEECCCEEECCCCCEEEEEEEECCCEEEEEECCCCHHHHHHH
CSAYDIIGELTLFTDNAKYLLNSKCLEDVEVGVIKREALEKELLQKPALVFEFMKWISEH
HHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
LRRMQTKFRDLVLHGKKGALYSTLIRMTNSYGVLKENGILIDLPLTNQELANFCATSRES
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEECCCEEEEECCCHHHHHHHHHCCHHH
VNRMLNELKKQGTISIHKGKITIHDLQFLKCEIACEDCSASVCSID
HHHHHHHHHHCCCEEEEECEEEEEHHEEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]