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The map label for this gene is ycbM [H]

Identifier: 30260459

GI number: 30260459

Start: 287864

End: 288808

Strand: Reverse

Name: ycbM [H]

Synonym: BA_0286

Alternate gene names: 30260459

Gene position: 288808-287864 (Counterclockwise)

Preceding gene: 30260460

Following gene: 30260458

Centisome position: 5.53

GC content: 33.65

Gene sequence:

>945_bases
ATGGATCCAAAAGTAAAAATTTCTTTATTTATTACCCTTATCTTAATTACAATGTATCTCTTCTTTTCAAGAATACAATT
TATTCAAAATCACAAATCAATAGACACTAAATTAAGTCGTGCACTAAAGGGGAATTTACAAACGAGATTATTCACAAGTA
ATGATCAATCGTTACATAATATCGTTTTTTCAATAAACGAACTAATAACTGAATTAGAAAAGGTTCGGATTAAAGCAAAA
AGGTCTGAGGAATCTAGAAAACAACTTTTATCTAGTATCTCACACGATATCCGAACACCACTCACCTCCATTATTGGATA
TATCGACGCTTTAAAAGATGGGGTTGCTGCTTCTGAAATAGAAAAGCAAGAATATCTTAAAATACTTTATATGAAATCAA
ATAACTTAAAGCACCTAGTTGATGAAATATTCAATATGGCAAAGCTAGACGCTAATGAATTTCCACTAAAAGAAGAAAAA
CTCGACTTTTCTGAAGTTACTAGAGAAGTTTTGATCGATTTTTTACCTGAAATCTCAAAACATAATATTAAACTGCAAGT
TCTTATGCCAGAGTCTACTTGTCCTATCATTGCAGATCACCTAAGCCTTATGCGGATTATAGGTAATTTAATGAAAAATG
CCATTTATTACGGAAAGGATGGGAAAACAATAGGAGTCGAACTACTAGAAACGGATGCAGCATATGAACTTCTTATTTGG
GACAAAGGCCCTGGTATTCCAAAACATGATTTACAAAACGTATTTGAGCGAATGTACCGAAGCGAACAATCAAGAAACTC
GTCTTTTGGTGGTAGTGGGCTCGGCCTTTCTATTTCTAAAGCGCTCGTTGAGAAGAATGGTGGGCATATATGGGTTGAAA
GTATTCCATGGGAACGAACCACTTTTGGCTTTTCCATTCCAAAACACAATACTTTTAAGAAATAG

Upstream 100 bases:

>100_bases
GGAATTGGCTATAAGTTTGTAGGTGAAAAGCTTGAAGATTGATAAAATCCTCTTCCTTATTTCATTACAACTTATCATTT
ACGGGCTTTTACATATACAA

Downstream 100 bases:

>100_bases
TTAAGAAATGATTAATATGCAGTTAAGCCTTCCTTTTTATCATGTAAGTAAGAACTTATAGAAAGTGGGTGTCTCCTATA
AACACAATTATAAAAACGAC

Product: sensor histidine kinase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQSLHNIVFSINELITELEKVRIKAK
RSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEK
LDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYYGKDGKTIGVELLETDAAYELLIW
DKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPWERTTFGFSIPKHNTFKK

Sequences:

>Translated_314_residues
MDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQSLHNIVFSINELITELEKVRIKAK
RSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEK
LDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYYGKDGKTIGVELLETDAAYELLIW
DKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPWERTTFGFSIPKHNTFKK
>Mature_314_residues
MDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQSLHNIVFSINELITELEKVRIKAK
RSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEK
LDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYYGKDGKTIGVELLETDAAYELLIW
DKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPWERTTFGFSIPKHNTFKK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=28.030303030303, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786912, Length=274, Percent_Identity=27.3722627737226, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=30.8270676691729, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=28.5140562248996, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=28.6885245901639, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=24.7899159663866, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=25.6637168141593, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786783, Length=252, Percent_Identity=26.5873015873016, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787894, Length=290, Percent_Identity=25.5172413793103, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=24.0384615384615, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=247, Percent_Identity=24.2914979757085, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=28.0851063829787, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=23.2456140350877, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35944; Mature: 35944

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQSLHN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
IVFSINELITELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISK
HHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHC
HNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYYGKDGKTIGVELLETDAAYELLIW
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEECCCCCEEEHEEEECCCCEEEEEE
DKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPWERT
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCC
TFGFSIPKHNTFKK
EECCCCCCCCCCCC
>Mature Secondary Structure
MDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQSLHN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
IVFSINELITELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISK
HHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHC
HNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYYGKDGKTIGVELLETDAAYELLIW
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEECCCCCEEEHEEEECCCCEEEEEE
DKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPWERT
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCC
TFGFSIPKHNTFKK
EECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]