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The map label for this gene is rnz [H]

Identifier: 30065587

GI number: 30065587

Start: 4540366

End: 4541133

Strand: Reverse

Name: rnz [H]

Synonym: S4646

Alternate gene names: 30065587

Gene position: 4541133-4540366 (Counterclockwise)

Preceding gene: 30065588

Following gene: 30065586

Centisome position: 98.73

GC content: 46.09

Gene sequence:

>768_bases
ATGGCAACGGCACTTATTATTGGCAATAAAACCTGGTTAATTGATGCTGGTTACGGGGCCAGCTTACAACTGGTAAAAAA
TAATATTCCACTGCGCCAGATTGATAATATTTTACTCACCCATTTACACAGTGATCATATTCTGGACTATCCATCAGTCT
TAATGAATGCATGGGCTAGCGGTCTGCAGGACAAAACTATTCATGTATTCGGTCCGCCAGGCACCCGAGCCATGACCGCT
GCCAGTTGGCAGGTCTTCGATCGGGACATCACACTGCGTATGGAAGAAGAAGGAAAACCCGATCCTCGCAAACTCGTTAC
AGCTCAAGATGTTGGTGAAGGCGTAGTTTATAAAGATGATACCGTGACCGTGACTGCATTAAAGGTCCCTCATTCTCCTT
TCCCTGACGGTGAGGCTTTTGCTTATCGCTTCGACACACAAGGCAAGCGAATTGTCTTCTCAGGAGATACCTCGTACTTT
CCCCCACTGGCAACTTTCTCAGAAGGCGCTGATATACTTGTGCATGAGGCCGTACATGAGCCCTCCGTCGCTAAGCTGGC
AGACAGTATTGGCAATGGTAAAACACTGGCAAAAGCCATTGCTTCTCACCATACGACTATTGAGGATGTAGGCAAAATTG
CCAATGAAGCAAAAGTGAAAAAACTCATCCTTAGCCACCTGGTACCAATCACCGTTCCGGATGAAACATGGAAGCAAGAA
GCACAGAAAACTATTCAGGTCCTATCGTCGTTGGTCATGAAAATATGA

Upstream 100 bases:

>100_bases
GCCAGTGGCATTCACCTACGCCTCCGAACCGCAATAAATGAAAATTGTACTACTTGGAACGAAAGGTGGCCCTTCTTTAT
TAAAAGCTGACCGTTTACCG

Downstream 100 bases:

>100_bases
CGATTACCATTCCATTCGCCCCATAAAAAATTCCGTCCCCGTTAGCCCTTGTTAGCGGGGAATATTATGATTTGCCTTAC
TGTAAGTTGATCACGATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MATALIIGNKTWLIDAGYGASLQLVKNNIPLRQIDNILLTHLHSDHILDYPSVLMNAWASGLQDKTIHVFGPPGTRAMTA
ASWQVFDRDITLRMEEEGKPDPRKLVTAQDVGEGVVYKDDTVTVTALKVPHSPFPDGEAFAYRFDTQGKRIVFSGDTSYF
PPLATFSEGADILVHEAVHEPSVAKLADSIGNGKTLAKAIASHHTTIEDVGKIANEAKVKKLILSHLVPITVPDETWKQE
AQKTIQVLSSLVMKI

Sequences:

>Translated_255_residues
MATALIIGNKTWLIDAGYGASLQLVKNNIPLRQIDNILLTHLHSDHILDYPSVLMNAWASGLQDKTIHVFGPPGTRAMTA
ASWQVFDRDITLRMEEEGKPDPRKLVTAQDVGEGVVYKDDTVTVTALKVPHSPFPDGEAFAYRFDTQGKRIVFSGDTSYF
PPLATFSEGADILVHEAVHEPSVAKLADSIGNGKTLAKAIASHHTTIEDVGKIANEAKVKKLILSHLVPITVPDETWKQE
AQKTIQVLSSLVMKI
>Mature_254_residues
ATALIIGNKTWLIDAGYGASLQLVKNNIPLRQIDNILLTHLHSDHILDYPSVLMNAWASGLQDKTIHVFGPPGTRAMTAA
SWQVFDRDITLRMEEEGKPDPRKLVTAQDVGEGVVYKDDTVTVTALKVPHSPFPDGEAFAYRFDTQGKRIVFSGDTSYFP
PLATFSEGADILVHEAVHEPSVAKLADSIGNGKTLAKAIASHHTTIEDVGKIANEAKVKKLILSHLVPITVPDETWKQEA
QKTIQVLSSLVMKI

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 27898; Mature: 27767

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATALIIGNKTWLIDAGYGASLQLVKNNIPLRQIDNILLTHLHSDHILDYPSVLMNAWAS
CCEEEEECCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
GLQDKTIHVFGPPGTRAMTAASWQVFDRDITLRMEEEGKPDPRKLVTAQDVGEGVVYKDD
CCCCCEEEEECCCCCCEEEEHHHEEECCEEEEEECCCCCCCHHHEEEHHHCCCCCEEECC
TVTVTALKVPHSPFPDGEAFAYRFDTQGKRIVFSGDTSYFPPLATFSEGADILVHEAVHE
EEEEEEEECCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEHHHCC
PSVAKLADSIGNGKTLAKAIASHHTTIEDVGKIANEAKVKKLILSHLVPITVPDETWKQE
CHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHH
AQKTIQVLSSLVMKI
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATALIIGNKTWLIDAGYGASLQLVKNNIPLRQIDNILLTHLHSDHILDYPSVLMNAWAS
CEEEEECCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
GLQDKTIHVFGPPGTRAMTAASWQVFDRDITLRMEEEGKPDPRKLVTAQDVGEGVVYKDD
CCCCCEEEEECCCCCCEEEEHHHEEECCEEEEEECCCCCCCHHHEEEHHHCCCCCEEECC
TVTVTALKVPHSPFPDGEAFAYRFDTQGKRIVFSGDTSYFPPLATFSEGADILVHEAVHE
EEEEEEEECCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEHHHCC
PSVAKLADSIGNGKTLAKAIASHHTTIEDVGKIANEAKVKKLILSHLVPITVPDETWKQE
CHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHH
AQKTIQVLSSLVMKI
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]