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The map label for this gene is aroB

Identifier: 30065327

GI number: 30065327

Start: 4285004

End: 4286092

Strand: Direct

Name: aroB

Synonym: S4355

Alternate gene names: 30065327

Gene position: 4285004-4286092 (Clockwise)

Preceding gene: 161486377

Following gene: 30065328

Centisome position: 93.17

GC content: 54.36

Gene sequence:

>1089_bases
ATGGAGAGGATTGTCGTTACTCTCGGGGAACGTAGTTACCCAATTACCATCGCATCTGGTTTGTTTAATGAACCAGCTTC
ATTCTTACCGCTGAAATCGGGCGAGCAGGTCATGTTGGTCACCAGCGAAACCCTGGCTCCTCTGTATCTCGATAAGGTCC
GCGGCGTACTTGAACAGGCGGGTGTTAACGTCGATAGCGTTATCCTCCCTGACGGCGAGCAGTATAAAAGCCTAGCTGTA
CTCGATACCGTCTTTACGGCGTTGTTACAAAAGCCGCATGGTCGCGATACTACGCTGGTGGCGCTTGGCGGCGGCGTAGT
GGGCGATCTGACCGGCTTCGCGGCGGCGAGTTATCAGCGCGGTGTTCGTTTCATTCAAGTCCCGACGACGTTACTGTCGC
AGGTCGATTCCTCCGTTGGCGGCAAAACTGCGGTCAACCATCCCCTCGGTAAAAACATGATTGGCGCGTTCTACCAGCCT
GCTTCAGTGGTGGTGGATCTCGACTGTCTGAAAACGCTTCCCCCGCGTGAGTTAGCGTCGGGGCTGGCAGAAGTCATCAA
ATACGGCATTATTCTTGACGGTGCGTTTTTTAACTGGCTGGAAGAGAATCTGGATGCGTTGTTGCGTCTGGACGGTCCGG
CAATGGCGTACTGTATTCGCCGTTGTTGTGAACTGAAGGCAGAAGTTGTCGCCGCCGACGAGCGCGAAACCGGGTTACGT
GCTTTACTGAATCTGGGACACACCTTTGGTCATGCCATTGAAGCTGAAATGGGGTATGGCAATTGGTTACATGGTGAAGC
GGTCGCTGCGGGTATGGTGATGGCGGCGCGGACGTCGGAACGTCTCGGGCAGTTTAGTTCTGCCGAAACGCAGCGTATTA
TAACCCTGCTCACGCGGGCTGGGTTACCGGTCAATGGGCCGCGCGAAATGTCCGCGCAGGCGTATTTACCGCATATGCTG
CGTGACAAGAAAGTCCTTGCGGGAGAGATGCGCTTAATTCTTCCGTTGGCAATTGGTAAGAGTGAAGTTCGCAGCGGCGT
TTCGCACGAGCTTGTTCTTAACGCCATTGCCGATTGTCAATCAGCGTAA

Upstream 100 bases:

>100_bases
AAGTGGTTGCAAACCAGATTATTCACATGCTGGAAAGCAACTAATTCTGGCTTTATATACACTCGTCTGCGGGTACAGTA
ATTAAGGTGGATGTCGCGTT

Downstream 100 bases:

>100_bases
CAACAAGAAAGGTCAGGCCGCTTATCAAGCGGTCTATTAGCTTCAGGTTAATTGCAACGTGGTAAGCATTAACCTTTTAG
TGGGGTGTTAAATGGATGAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTSETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAV
LDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHML
RDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA

Sequences:

>Translated_362_residues
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTSETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAV
LDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHML
RDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
>Mature_362_residues
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTSETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAV
LDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHML
RDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=362, Percent_Identity=99.4475138121547, Blast_Score=733, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320332, Length=312, Percent_Identity=38.7820512820513, Blast_Score=194, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38827; Mature: 38827

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTSETLAPLYLDKVRGVLEQA
CCEEEEEECCCCCCEEEECCCCCCCCHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
GVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQR
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHCCCCHHHHHH
GLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRA
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQ
CCCCCCCHHCCHHHHHHHHHHCCHHHHCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHC
SA
CC
>Mature Secondary Structure
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTSETLAPLYLDKVRGVLEQA
CCEEEEEECCCCCCEEEECCCCCCCCHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
GVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQR
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELAS
CCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHCCCCHHHHHH
GLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRA
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQ
CCCCCCCHHCCHHHHHHHHHHCCHHHHCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHC
SA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA