Click here to switch to the map view.

The map label for this gene is arsR

Identifier: 30065212

GI number: 30065212

Start: 4146620

End: 4146964

Strand: Direct

Name: arsR

Synonym: S4232

Alternate gene names: 30065212

Gene position: 4146620-4146964 (Clockwise)

Preceding gene: 30065206

Following gene: 30065213

Centisome position: 90.16

GC content: 49.86

Gene sequence:

>345_bases
CTGTTACCCATCCAATTGTTCAAAATTCTTGCTGATGAAACCCGTCTGGGCATCGTTTTACTGCTTAGCGAACTGGGAGA
GTTATGCGTCTGCGATCTCTGCACTGCCCTCGATCAGTCGCAGCCCAAGATATCCCGCCATCTGGCATTGCTGCGTGAAA
GCGGGCTATTGCTGGACCGCAAGCAAGGTAAGTGGGTTCATTACCGCTTATCGCCGCATATTCCAGCATGGGCGGCGAAA
ATTATTGATGAAGCCTGGCGATGTGAACAGGAAAAGATTCAGGCAATTGTCCGCAACCTGGCCAGACAAAACTGTTCCGG
AGACAGTAAGAACATTTGCAGTTAA

Upstream 100 bases:

>100_bases
TTCAGTAGCGGAGCAGGAAGGACATCTGATGGAAATGGAAGCCACGCAAGCACCTTAAAATCACCATCATACACTAAATC
AGTAAGTTGGCAGCATTACC

Downstream 100 bases:

>100_bases
AAATTTAGCTAAACACATATGGATTTGCACATGTGTTTTATCCGGGAGGCATTATGTTACTGGCAGGCGCTATCTTTGTC
CTGACCATCGTATTGGTTAT

Product: DNA-binding transcriptional repressor ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAK
IIDEAWRCEQEKIQAIVRNLARQNCSGDSKNICS

Sequences:

>Translated_114_residues
MLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAK
IIDEAWRCEQEKIQAIVRNLARQNCSGDSKNICS
>Mature_114_residues
MLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAK
IIDEAWRCEQEKIQAIVRNLARQNCSGDSKNICS

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=114, Percent_Identity=98.2456140350877, Blast_Score=229, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12919; Mature: 12919

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDR
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEC
KQGKWVHYRLSPHIPAWAAKIIDEAWRCEQEKIQAIVRNLARQNCSGDSKNICS
CCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDR
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEC
KQGKWVHYRLSPHIPAWAAKIIDEAWRCEQEKIQAIVRNLARQNCSGDSKNICS
CCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]