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The map label for this gene is sat [H]

Identifier: 30064971

GI number: 30064971

Start: 3860121

End: 3860627

Strand: Direct

Name: sat [H]

Synonym: S3965

Alternate gene names: 30064971

Gene position: 3860121-3860627 (Clockwise)

Preceding gene: 30064968

Following gene: 30064974

Centisome position: 83.93

GC content: 44.18

Gene sequence:

>507_bases
ATGTTCACAACAAAAGGTATTGATATCTCCGGTGAACTGACTATGATGGGAATCCCTGAACAGAATAGTAAAACTGTAAC
GCCGGGTCTCCACTACGCTGCTGATGGATTCAGGCTGAGTGGTGGAAATGCAAATTTCATTGCCAGAAATATGGCATCTG
TCACCGGAAATATTTATGCTGATGATGCAGCAACCATTACTCTGGGACAGCCTGAAACTGAAACACCGACTATATCGTCT
GCTTATCAGGCATGGGCAGAGACTCTTTTGTATGGCTTTGATACCGCCTATCGAGGCGCAATAACAGCCCCCAAAGCTAC
AGTTAGCATGAATAATGCGATCTGGCATCTAAATAGCCAGTCATCAATTAATCGTCTAGAAACAAAAGACAGTATGGTGC
GTTTTACTGGTGACAATGGGAAGTTTACAACCCTTACAGTGGACAACCTTACTATAGATGACAGTGCATTTGTGCTGCGT
GCAAATCTGGCCCAAGCAGATCAGTGA

Upstream 100 bases:

>100_bases
CATAGGTGATCAAGCTGTAGTTACACTTAATGGTGCAACCTTTCTGAATAATACTCCTATAAGTATAGATAAAGGAGCAA
AAGTTATAGCACAAAATTCC

Downstream 100 bases:

>100_bases
GGTGTACTGGCAATAGCGGACACTACCATTTGTTCTTTTTTTAAGCAGCCATCTGATGATATTTTTCCCTGAAGGCTGCC
GGGGAGATATTCCCCAGACG

Product: putative secreted autotransporter toxin

Products: NA

Alternate protein names: Secreted autotransporter toxin sat [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MFTTKGIDISGELTMMGIPEQNSKTVTPGLHYAADGFRLSGGNANFIARNMASVTGNIYADDAATITLGQPETETPTISS
AYQAWAETLLYGFDTAYRGAITAPKATVSMNNAIWHLNSQSSINRLETKDSMVRFTGDNGKFTTLTVDNLTIDDSAFVLR
ANLAQADQ

Sequences:

>Translated_168_residues
MFTTKGIDISGELTMMGIPEQNSKTVTPGLHYAADGFRLSGGNANFIARNMASVTGNIYADDAATITLGQPETETPTISS
AYQAWAETLLYGFDTAYRGAITAPKATVSMNNAIWHLNSQSSINRLETKDSMVRFTGDNGKFTTLTVDNLTIDDSAFVLR
ANLAQADQ
>Mature_168_residues
MFTTKGIDISGELTMMGIPEQNSKTVTPGLHYAADGFRLSGGNANFIARNMASVTGNIYADDAATITLGQPETETPTISS
AYQAWAETLLYGFDTAYRGAITAPKATVSMNNAIWHLNSQSSINRLETKDSMVRFTGDNGKFTTLTVDNLTIDDSAFVLR
ANLAQADQ

Specific function: Shows serine protease activity and displays cytophatic activity, including elongation, rounding, and detachment of a proportion of the cells from monolayer in culture. Triggers vacuolation within the cytoplasm of the human bladder and kidney cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Serine protease sat translocator:Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase S6 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005546
- InterPro:   IPR006315
- InterPro:   IPR012332
- InterPro:   IPR011050
- InterPro:   IPR000710 [H]

Pfam domain/function: PF03797 Autotransporter; PF02395 Peptidase_S6 [H]

EC number: NA

Molecular weight: Translated: 18069; Mature: 18069

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTTKGIDISGELTMMGIPEQNSKTVTPGLHYAADGFRLSGGNANFIARNMASVTGNIYA
CCCCCCCCCCCCEEEEECCCCCCEEECCCCEEECCCEEEECCCCCEEEECHHHHCCCEEE
DDAATITLGQPETETPTISSAYQAWAETLLYGFDTAYRGAITAPKATVSMNNAIWHLNSQ
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCEECCCCEEEEECCEEEEECCC
SSINRLETKDSMVRFTGDNGKFTTLTVDNLTIDDSAFVLRANLAQADQ
CCCHHHCCCCCEEEEECCCCEEEEEEECCEEECCCEEEEEECCCCCCC
>Mature Secondary Structure
MFTTKGIDISGELTMMGIPEQNSKTVTPGLHYAADGFRLSGGNANFIARNMASVTGNIYA
CCCCCCCCCCCCEEEEECCCCCCEEECCCCEEECCCEEEECCCCCEEEECHHHHCCCEEE
DDAATITLGQPETETPTISSAYQAWAETLLYGFDTAYRGAITAPKATVSMNNAIWHLNSQ
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCEECCCCEEEEECCEEEEECCC
SSINRLETKDSMVRFTGDNGKFTTLTVDNLTIDDSAFVLRANLAQADQ
CCCHHHCCCCCEEEEECCCCEEEEEEECCEEECCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11029690; 12471157 [H]