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The map label for this gene is atpH

Identifier: 30064960

GI number: 30064960

Start: 3845623

End: 3846156

Strand: Direct

Name: atpH

Synonym: S3953

Alternate gene names: 30064960

Gene position: 3845623-3846156 (Clockwise)

Preceding gene: 30064959

Following gene: 30064961

Centisome position: 83.61

GC content: 51.31

Gene sequence:

>534_bases
ATGTCTGAATTTATTACGGTAGCTCGCCCCTACGCCAAAGCAGCTTTTGACTTTGCCGTCGAACACCAAAGTGTAGAACG
CTGGCAGGACATGCTGACGTTTGCCGCCGAGGTAACCAAAAACGAACAAATGGCAGAGCTTCTCTCTGGCGCGCTTGCGC
CAGAAACGCTCGCCGAGTCGTTTATCGCAGTTTGTGGTGAGCAACTGGACGAAAACGGTCAGAACCTGATTCGGGTAATG
GCTGAAAATGGTCGTCTTAACGCGCTCCCGGATGTTCTGGAGCAGTTTATTCACCTTCGTGCCGTGAGTGAGGCTACCGC
TGAGGTAGACGTCATTTCCGCTGCCGCACTGAGTGAACAACAGCTCGCGAAAATTTCTGCTGCGATGGAAAAACGTCTGT
CACGCAAAGTTAAGCTGAATTGCAAAATCGATAAGTCTGTAATGGCTGGCGTTATCATCCGATCGGGTGATATGGTCATT
GATGGCAGCGTACGCGGTCGTCTTGAGCGCCTTGCAGACGTCTTGCAGTCTTAA

Upstream 100 bases:

>100_bases
TTGCTGGCGCCGAGAAGATCATCGAACGTTCCGTGGATGAAGCTGCTAACAGCGACATCGTGGATAAACTTGTCGCTGAA
CTGTAAGGAGGGAGGGGCTG

Downstream 100 bases:

>100_bases
GGGGACTGGAGCATGCAACTGAATTCCACCGAAATCAGCGAACTGATCAAGCAGCGCATTGCTCAGTTCAATGTTGTGAG
TGAAGCTCACAACGAAGGTA

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MSEFITVARPYAKAAFDFAVEHQSVERWQDMLTFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVM
AENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRSGDMVI
DGSVRGRLERLADVLQS

Sequences:

>Translated_177_residues
MSEFITVARPYAKAAFDFAVEHQSVERWQDMLTFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVM
AENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRSGDMVI
DGSVRGRLERLADVLQS
>Mature_176_residues
SEFITVARPYAKAAFDFAVEHQSVERWQDMLTFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMA
ENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRSGDMVID
GSVRGRLERLADVLQS

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction [H]

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family [H]

Homologues:

Organism=Homo sapiens, GI4502303, Length=170, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1790173, Length=177, Percent_Identity=98.8700564971751, Blast_Score=354, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000711
- InterPro:   IPR020781 [H]

Pfam domain/function: PF00213 OSCP [H]

EC number: 3.6.3.14

Molecular weight: Translated: 19378; Mature: 19247

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFITVARPYAKAAFDFAVEHQSVERWQDMLTFAAEVTKNEQMAELLSGALAPETLAES
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHH
FIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQ
HHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRSGDMVIDGSVRGRLERLADVLQS
HHHHHHHHHHHHHHHHEEEECEECHHHHHHHHEECCCEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEFITVARPYAKAAFDFAVEHQSVERWQDMLTFAAEVTKNEQMAELLSGALAPETLAES
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHH
FIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQ
HHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRSGDMVIDGSVRGRLERLADVLQS
HHHHHHHHHHHHHHHHEEEECEECHHHHHHHHEECCCEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA