| Definition | Shigella flexneri 2a str. 2457T, complete genome. |
|---|---|
| Accession | NC_004741 |
| Length | 4,599,354 |
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The map label for this gene is sorD
Identifier: 30064699
GI number: 30064699
Start: 3519483
End: 3520289
Strand: Direct
Name: sorD
Synonym: S3637
Alternate gene names: 30064699
Gene position: 3519483-3520289 (Clockwise)
Preceding gene: 30064698
Following gene: 30064700
Centisome position: 76.52
GC content: 50.93
Gene sequence:
>807_bases ATGCAAACGTGGTTAAATTTGCAGGATAAAATCATTATTGTCACCGGCGGCGCATCCGGTATTGGTCTGGCGATTGTAGA GGAATTATTAGCACAAGGCGCGAATGTACAGATGGTCGATATTCACGGTGGCGATGGTCAATATGAAGGTCATAAAGGCT ATCAGTTTTGGCCGACCGATATTTCTAGCACAAAAGAGGTAAATCATACGGTAGCGGAAATTATCCAGCGTTTTGGTCGC ATCGACGGTCTGGTCAATAACGCCGGGGTCAATTTCCCGCGTCTGCTGGTCGATGAGAAAGCGCCTGCCGGGCAGTATGA ACTCAACGAAGCTGCATTCGAAAAAATGGTCAATATCAACCAGAAAGGTGTTTTTCTGATGTCGCAGGCGGTGGCGCGAC AGATGGTCAAACAACATGATGGCGTGATTGTGAATGTTTCCTCAGAAAGTGGGCTGGAAGGCTCAGAAGGACAAAGCTGT TACGCCGCTACCAAAGCCGCGCTCAATAGCTTCACGCGCTCCTGGTCGAAAGAGCTGGGTAAACACGGTATCCGTGTGGT CGGTATCGCGCCCGGGATTCTGGAAAAAACCGGGCTACGCACGCCGGAATATGAAGAGGCGCTGGCGTGGACGCGCAATA TCACCGTCGAGCAGCTGCGTGAAGGCTATACCAAAAACGCCATTCCTATTGGGCGCGCCGGAAGATTAGCAGAAGTAGCT GATTTTGTTTGTTATCTGTTGTCTGAACGCGCCAGCTACATCACCGGAGTAACCACTAACATTGCGGGCGGCAAAACGCG CGGCTAA
Upstream 100 bases:
>100_bases TAGCAGCACAGCTGAACTATTACTGAAATAAAAATCTTCCCGATGTTTACCGTAATAAAAATTACGGCGGGTCCCTATTA TCTAAAATCAGGAGTCTGTT
Downstream 100 bases:
>100_bases GGAGGCTTTATGGTCAACGCCATTTTTTGTGCCCACGGCAAATTAGCTTGCGCCATGCTGGAATCGGTTCAGATGGTTTA CGGCAACGCCAATGTTGAAG
Product: sorbitol-6-phosphate 2-dehydrogenase
Products: NA
Alternate protein names: Glucitol-6-phosphate dehydrogenase; Ketosephosphate reductase [H]
Number of amino acids: Translated: 268; Mature: 268
Protein sequence:
>268_residues MQTWLNLQDKIIIVTGGASGIGLAIVEELLAQGANVQMVDIHGGDGQYEGHKGYQFWPTDISSTKEVNHTVAEIIQRFGR IDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA DFVCYLLSERASYITGVTTNIAGGKTRG
Sequences:
>Translated_268_residues MQTWLNLQDKIIIVTGGASGIGLAIVEELLAQGANVQMVDIHGGDGQYEGHKGYQFWPTDISSTKEVNHTVAEIIQRFGR IDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA DFVCYLLSERASYITGVTTNIAGGKTRG >Mature_268_residues MQTWLNLQDKIIIVTGGASGIGLAIVEELLAQGANVQMVDIHGGDGQYEGHKGYQFWPTDISSTKEVNHTVAEIIQRFGR IDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA DFVCYLLSERASYITGVTTNIAGGKTRG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=262, Percent_Identity=32.0610687022901, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI15277342, Length=276, Percent_Identity=30.7971014492754, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI10190704, Length=266, Percent_Identity=31.9548872180451, Blast_Score=110, Evalue=9e-25, Organism=Homo sapiens, GI4758504, Length=193, Percent_Identity=33.6787564766839, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI19923817, Length=273, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI32483357, Length=276, Percent_Identity=31.5217391304348, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI59889578, Length=245, Percent_Identity=30.2040816326531, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI31542939, Length=218, Percent_Identity=33.0275229357798, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI83715985, Length=183, Percent_Identity=31.6939890710383, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=28.4090909090909, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=34.0659340659341, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI66933014, Length=260, Percent_Identity=29.2307692307692, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=26.2376237623762, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI126723750, Length=270, Percent_Identity=27.037037037037, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI5031737, Length=269, Percent_Identity=27.8810408921933, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=236, Percent_Identity=27.5423728813559, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=271, Percent_Identity=33.9483394833948, Blast_Score=124, Evalue=8e-30, Organism=Escherichia coli, GI87082100, Length=269, Percent_Identity=31.5985130111524, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1790717, Length=271, Percent_Identity=29.1512915129151, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI1788459, Length=206, Percent_Identity=33.9805825242718, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=27.5471698113208, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI2367175, Length=267, Percent_Identity=31.4606741573034, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1786812, Length=267, Percent_Identity=28.0898876404494, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1787905, Length=269, Percent_Identity=28.6245353159851, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1789057, Length=273, Percent_Identity=27.1062271062271, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI1789378, Length=280, Percent_Identity=28.2142857142857, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=26.5625, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=194, Percent_Identity=28.3505154639175, Blast_Score=71, Evalue=8e-14, Organism=Caenorhabditis elegans, GI25147288, Length=265, Percent_Identity=33.5849056603774, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17555706, Length=267, Percent_Identity=32.9588014981273, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17561402, Length=271, Percent_Identity=31.3653136531365, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562908, Length=275, Percent_Identity=29.0909090909091, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=29.7101449275362, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI115534694, Length=273, Percent_Identity=29.6703296703297, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=29.4776119402985, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562990, Length=277, Percent_Identity=30.6859205776173, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=28.6764705882353, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17562910, Length=279, Percent_Identity=27.9569892473118, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17560150, Length=277, Percent_Identity=28.5198555956679, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17538182, Length=214, Percent_Identity=29.9065420560748, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17562904, Length=277, Percent_Identity=29.9638989169675, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=30.6273062730627, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994600, Length=206, Percent_Identity=27.1844660194175, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17559104, Length=276, Percent_Identity=26.8115942028986, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI71994604, Length=265, Percent_Identity=27.1698113207547, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560332, Length=280, Percent_Identity=29.2857142857143, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=28.7272727272727, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17531453, Length=276, Percent_Identity=29.7101449275362, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17560676, Length=277, Percent_Identity=26.7148014440433, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI193204405, Length=218, Percent_Identity=33.0275229357798, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17565030, Length=277, Percent_Identity=29.6028880866426, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=27.3062730627306, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=27.7372262773723, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536025, Length=274, Percent_Identity=25.9124087591241, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508895, Length=201, Percent_Identity=26.865671641791, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17567345, Length=205, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=24.4019138755981, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17508651, Length=211, Percent_Identity=24.1706161137441, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6324126, Length=273, Percent_Identity=27.1062271062271, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=263, Percent_Identity=28.1368821292776, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI23397609, Length=267, Percent_Identity=33.7078651685393, Blast_Score=130, Evalue=7e-31, Organism=Drosophila melanogaster, GI24639444, Length=265, Percent_Identity=32.8301886792453, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI24643142, Length=266, Percent_Identity=32.3308270676692, Blast_Score=102, Evalue=4e-22, Organism=Drosophila melanogaster, GI21357041, Length=268, Percent_Identity=30.2238805970149, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI21355319, Length=276, Percent_Identity=29.7101449275362, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI28571526, Length=281, Percent_Identity=29.8932384341637, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI17737361, Length=209, Percent_Identity=33.0143540669856, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24644339, Length=276, Percent_Identity=26.8115942028986, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI24644337, Length=223, Percent_Identity=30.9417040358744, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24665243, Length=204, Percent_Identity=31.3725490196078, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=30.8457711442786, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24665247, Length=205, Percent_Identity=31.219512195122, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI21356301, Length=207, Percent_Identity=29.4685990338164, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=30.6930693069307, Blast_Score=70, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.140 [H]
Molecular weight: Translated: 29039; Mature: 29039
Theoretical pI: Translated: 6.37; Mature: 6.37
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQTWLNLQDKIIIVTGGASGIGLAIVEELLAQGANVQMVDIHGGDGQYEGHKGYQFWPTD CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEECCCC ISSTKEVNHTVAEIIQRFGRIDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNIN CCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHEECCCCCCCCCHHHHHHHHHHHCCC QKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSCYAATKAALNSFTRSWSKELG CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH KHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA HCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHH DFVCYLLSERASYITGVTTNIAGGKTRG HHHHHHHHHHHHHHHCCEEECCCCCCCC >Mature Secondary Structure MQTWLNLQDKIIIVTGGASGIGLAIVEELLAQGANVQMVDIHGGDGQYEGHKGYQFWPTD CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEECCCC ISSTKEVNHTVAEIIQRFGRIDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNIN CCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHEECCCCCCCCCHHHHHHHHHHHCCC QKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSCYAATKAALNSFTRSWSKELG CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH KHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEVA HCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHH DFVCYLLSERASYITGVTTNIAGGKTRG HHHHHHHHHHHHHHHCCEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7947968; 7652212 [H]