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The map label for this gene is yphC

Identifier: 30063934

GI number: 30063934

Start: 2653160

End: 2654254

Strand: Reverse

Name: yphC

Synonym: S2764

Alternate gene names: 30063934

Gene position: 2654254-2653160 (Counterclockwise)

Preceding gene: 30063935

Following gene: 30063933

Centisome position: 57.71

GC content: 54.16

Gene sequence:

>1095_bases
ATGAAAATTAATCGTATTGTTAATGAGGGATTTATGAAAACGATGCTGGCTGCTTATTTACTAGGAAATTCAACCGTCGA
TCTGCGGGAAGTTGCGGTGCCGACGCCGGGGATTAACCAGGTACTGATCAAAATGAAATCCTCCGGGATTTGCGGAAGCG
ATGTCCACTATATCTATCATCAACACCGTGCCACGGCGGCGGCACCCGATAAACCGTTATACCAGGGATTTATCAACGGT
CATGAACCGTGCGGGCAGATTGTGGCGATGGGGCAAGGCTGCCGCCATTTTAAAGAGGGCGACCGCGTGCTGGTGTATCA
CATTTCTGGCTGTGGTTTTTGCCCGAACTGCCGCCGCGGCTTTCCTATCTCTTGTACTGGCAAAGGAAAAGCGGCTTACG
GCTGGCAGCGTGACGGCGGTCATGCCGAATATCTGCTGGCGGAAGAAAAAGATCTGATCCTCCTGCCGGATGCGCTGAGC
TACGAAGATGGTGCGTTTATCAGTTGCGGCGTTGGCACGGCCTATGAAGGGATTTTGCGCGGCGAAGTTTCCGGCAGCGA
TAACGTGCTGGTGGTCGGTCTGGGGCCGGTCGGCATGATGGCGATGATGCTGGCGAAAGGTCGCGGTGCAAAACGGATCA
TCGGCGTTGATATGCTGCCGGAACGTCTGGCGATGGCAAAACAGTTAGGGGGGATGGATCACGGCTATTTAGCAACCACC
GAAGGTCTGCCGCAGATAATTGCTGAACTTACCCACGGTGGCGCGGATGTTGCGCTCGATTGTTCCGGTAATGCCGCAGG
TCGCTTGCTGGCACTGCAATCCACTGCTGACTGGGGGCGGGTGGTTTACATTGGTGAAACCGGAAAAGTGGAATTCGAGG
TCAGCGCTGATCTGATGCACCATCAACGGCGGATTATCGGCTCCTGGGTGACCAGTCTGTTCCATATGGAAAAATGCGCC
CACGATTTGACTGACTGGAAGCTGTGGCCGCGTAACGCCATTACCCATCGCTTCTCGCTAGAACAGGCAGGTGATGCCTA
TGTGCTGATGGCGAGCGGCAAATGCGGGAAAGTTGTGATTAACTTCCCGGATTAA

Upstream 100 bases:

>100_bases
TCATCATCGTGGTGGCGGTGCTGGCGAATATCTTGCTGACCCAGCGAAGCAGTAAAGCGAAACGCTAAACCTTAACGCCC
CTGGCGCGGGTGCTGCAGGG

Downstream 100 bases:

>100_bases
GGAGTTAGCGGATGACCATCTATACCTTATCCCACGGGTCGCTAAAGCTGGACGTTTCTGACCAGGGCGGCGTAATCGAA
GGCTTCTGGCGCGATACGAC

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKINRIVNEGFMKTMLAAYLLGNSTVDLREVAVPTPGINQVLIKMKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFING
HEPCGQIVAMGQGCRHFKEGDRVLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDMLPERLAMAKQLGGMDHGYLATT
EGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTADWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCA
HDLTDWKLWPRNAITHRFSLEQAGDAYVLMASGKCGKVVINFPD

Sequences:

>Translated_364_residues
MKINRIVNEGFMKTMLAAYLLGNSTVDLREVAVPTPGINQVLIKMKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFING
HEPCGQIVAMGQGCRHFKEGDRVLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDMLPERLAMAKQLGGMDHGYLATT
EGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTADWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCA
HDLTDWKLWPRNAITHRFSLEQAGDAYVLMASGKCGKVVINFPD
>Mature_364_residues
MKINRIVNEGFMKTMLAAYLLGNSTVDLREVAVPTPGINQVLIKMKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFING
HEPCGQIVAMGQGCRHFKEGDRVLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDMLPERLAMAKQLGGMDHGYLATT
EGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTADWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCA
HDLTDWKLWPRNAITHRFSLEQAGDAYVLMASGKCGKVVINFPD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565152, Length=365, Percent_Identity=26.8493150684932, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI156523966, Length=360, Percent_Identity=27.2222222222222, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4501939, Length=354, Percent_Identity=27.4011299435028, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI156627571, Length=354, Percent_Identity=26.8361581920904, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI262073058, Length=384, Percent_Identity=23.6979166666667, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4501929, Length=365, Percent_Identity=25.2054794520548, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI71743840, Length=363, Percent_Identity=23.9669421487603, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4501933, Length=369, Percent_Identity=24.9322493224932, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI34577061, Length=365, Percent_Identity=25.2054794520548, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI71565154, Length=364, Percent_Identity=24.1758241758242, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI194239674, Length=355, Percent_Identity=26.7605633802817, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI13236495, Length=355, Percent_Identity=26.7605633802817, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87082125, Length=353, Percent_Identity=98.8668555240793, Blast_Score=720, Evalue=0.0,
Organism=Escherichia coli, GI1790045, Length=344, Percent_Identity=31.3953488372093, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787863, Length=348, Percent_Identity=29.0229885057471, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788407, Length=322, Percent_Identity=28.5714285714286, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788073, Length=261, Percent_Identity=29.8850574712644, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI226510992, Length=324, Percent_Identity=25.6172839506173, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788075, Length=378, Percent_Identity=27.2486772486773, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786825, Length=261, Percent_Identity=27.9693486590038, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786552, Length=385, Percent_Identity=25.1948051948052, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081918, Length=350, Percent_Identity=26.5714285714286, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790718, Length=256, Percent_Identity=26.953125, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=274, Percent_Identity=32.4817518248175, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562878, Length=251, Percent_Identity=29.8804780876494, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25146526, Length=372, Percent_Identity=23.3870967741935, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71988145, Length=341, Percent_Identity=24.633431085044, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71997431, Length=374, Percent_Identity=23.2620320855615, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565904, Length=401, Percent_Identity=22.9426433915212, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562584, Length=349, Percent_Identity=26.647564469914, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562582, Length=306, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319955, Length=323, Percent_Identity=28.4829721362229, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6322619, Length=323, Percent_Identity=28.4829721362229, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323099, Length=351, Percent_Identity=26.2108262108262, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320033, Length=383, Percent_Identity=23.2375979112272, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319257, Length=352, Percent_Identity=24.1477272727273, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=259, Percent_Identity=25.4826254826255, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=293, Percent_Identity=24.9146757679181, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319258, Length=265, Percent_Identity=29.0566037735849, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=267, Percent_Identity=26.9662921348315, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=262, Percent_Identity=24.0458015267176, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17137530, Length=266, Percent_Identity=30.8270676691729, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17737895, Length=365, Percent_Identity=25.4794520547945, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17737897, Length=267, Percent_Identity=29.5880149812734, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI221457811, Length=336, Percent_Identity=23.2142857142857, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI45551930, Length=336, Percent_Identity=23.2142857142857, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI45550770, Length=336, Percent_Identity=23.2142857142857, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 39355; Mature: 39355

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINRIVNEGFMKTMLAAYLLGNSTVDLREVAVPTPGINQVLIKMKSSGICGSDVHYIYH
CCCHHHHHHHHHHHHHHHHHHCCCCEEHHEEECCCCCCCCEEEEEECCCCCCCCHHHHHH
QHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDRVLVYHISGCGFCPNCRRG
HHCCCCCCCCCHHHHHHCCCCCCHHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCCCCCC
FPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALSYEDGAFISCGVGTAYEGILR
CCEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCEEEECCCHHHHHEEE
GEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDMLPERLAMAKQLGGMDHGYLATT
EECCCCCCEEEEEECHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEC
EGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTADWGRVVYIGETGKVEFEVSADLMH
CCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEECHHHHH
HQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAITHRFSLEQAGDAYVLMASGKCGKVVI
HHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHEEEEECCCCCCEEEEEECCCCCEEEE
NFPD
ECCC
>Mature Secondary Structure
MKINRIVNEGFMKTMLAAYLLGNSTVDLREVAVPTPGINQVLIKMKSSGICGSDVHYIYH
CCCHHHHHHHHHHHHHHHHHHCCCCEEHHEEECCCCCCCCEEEEEECCCCCCCCHHHHHH
QHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDRVLVYHISGCGFCPNCRRG
HHCCCCCCCCCHHHHHHCCCCCCHHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCCCCCC
FPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALSYEDGAFISCGVGTAYEGILR
CCEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCEEEECCCHHHHHEEE
GEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDMLPERLAMAKQLGGMDHGYLATT
EECCCCCCEEEEEECHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEC
EGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTADWGRVVYIGETGKVEFEVSADLMH
CCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEECHHHHH
HQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAITHRFSLEQAGDAYVLMASGKCGKVVI
HHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHEEEEECCCCCCEEEEEECCCCCEEEE
NFPD
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]