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The map label for this gene is yfeT

Identifier: 30063820

GI number: 30063820

Start: 2520247

End: 2521047

Strand: Reverse

Name: yfeT

Synonym: S2628

Alternate gene names: 30063820

Gene position: 2521047-2520247 (Counterclockwise)

Preceding gene: 30063823

Following gene: 30063819

Centisome position: 54.81

GC content: 52.43

Gene sequence:

>801_bases
ATGTTGTACCTGACGAAAATACGCAATGCGGAAAGTGAATTTACCGGGAACGAGCAAAAAATTGCTGACTTTCTGCGGGC
CAGAGTGAGCGAGCTGAAATCCGTCTCTTCACGGCAGATGGCGAAACAGCTCGGTATCAGCCAGTCGAGCATTGTGAAAT
TTGCCCAGAAGCTCGGCGCGCAAGGATTTACTGAATTGCGTATGGCGTTAATTGGCGAATACAGTGCCAGCCGGGAGAAA
ACGAATGCCACGGCGCTGCACCTGCACAGTTCGATTACCAGTGATGATTCGCTGGAAGTGATTGCCCGCAAACTGAATCG
CGAAAAAGAGCTGGCGCTGGAGCAAACCTGTGCGTTGTTCGACTACGCGCGGCTGCAAAAAATCATTGAGGTCATCAGTA
AAGCACCGTTTATCCAGATAACGGGCCTGGGCGGATCGGCGCTGGTGGGGCGCGATCTGTCGTTCAAACTGATGAAAATT
GGCTATCGCGTGGCCTGCGAAGCCGACACGCACGTACAAGCCACCGTTTCCCAGGCGTTGAAAAAAGGCGATGTACAAAT
CGCTATCTCTTACAGCGGCAGTAAAAAAGAGATTGTCTTGTGCGCAGAAGCGGCACGAAAGCAGGGGGCAACGGTGATTG
CCATTACTTCTCTGGCTGACTCTCCGCTGCGGCGGCTGGCGCATTTCACGCTCGATACCGTTTCCGGTGAAACCGAATGG
CGTAGCTCGTCGATGTCTACCCGCACGGCGCAAAATTCTGTTACCGATTTACTGTTTGTTGGTCTTGTGCAACATCAATG
A

Upstream 100 bases:

>100_bases
TGACAGACTTAAAGGAATCATTGAGTCTACACTCGCAGAGTGTGAAGAGCGTCATAAGAACTTAAGCGGAATTTTTGCTG
CCAGCCCAGGAGAGTGGAAG

Downstream 100 bases:

>100_bases
TGTGGCGTCATTGAAAATGATTCAGCGCAGCAGTGAGCTAACACAACGCCTGAAATGATGCATAAAGCAGCGACTGGATT
GAGATTTTCCTGAATTAGTG

Product: hypothetical protein

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLYLTKIRNAESEFTGNEQKIADFLRARVSELKSVSSRQMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREK
TNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEW
RSSSMSTRTAQNSVTDLLFVGLVQHQ

Sequences:

>Translated_266_residues
MLYLTKIRNAESEFTGNEQKIADFLRARVSELKSVSSRQMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREK
TNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEW
RSSSMSTRTAQNSVTDLLFVGLVQHQ
>Mature_266_residues
MLYLTKIRNAESEFTGNEQKIADFLRARVSELKSVSSRQMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREK
TNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEW
RSSSMSTRTAQNSVTDLLFVGLVQHQ

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=264, Percent_Identity=96.969696969697, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI87082130, Length=261, Percent_Identity=35.632183908046, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI87082369, Length=258, Percent_Identity=25.1937984496124, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788159, Length=264, Percent_Identity=27.6515151515151, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 29130; Mature: 29130

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLTKIRNAESEFTGNEQKIADFLRARVSELKSVSSRQMAKQLGISQSSIVKFAQKLGA
CEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
QGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALF
CCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
DYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQAL
HHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCHHHHHHCCEEEEECCCCHHHHHHHHHH
KKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEW
HCCCEEEEEEECCCCCEEEEEEHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHH
RSSSMSTRTAQNSVTDLLFVGLVQHQ
HCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYLTKIRNAESEFTGNEQKIADFLRARVSELKSVSSRQMAKQLGISQSSIVKFAQKLGA
CEEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
QGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIARKLNREKELALEQTCALF
CCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
DYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKIGYRVACEADTHVQATVSQAL
HHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCHHHHHHCCEEEEECCCCHHHHHHHHHH
KKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEW
HCCCEEEEEEECCCCCEEEEEEHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHH
RSSSMSTRTAQNSVTDLLFVGLVQHQ
HCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA