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The map label for this gene is mntH

Identifier: 30063796

GI number: 30063796

Start: 2492445

End: 2493683

Strand: Reverse

Name: mntH

Synonym: S2597

Alternate gene names: 30063796

Gene position: 2493683-2492445 (Counterclockwise)

Preceding gene: 30063801

Following gene: 30063792

Centisome position: 54.22

GC content: 53.03

Gene sequence:

>1239_bases
ATGACGAACTATCGCGTTGAGAGTAGCAGCGGACGGGCGGCGCGTAAGATGAGGCTCGCATTAATGGGACCTGCGTTCAT
TGCGGCGATTGGTTATATCGATCCCGGTAACTTTGCGACCAATATTCAGGCGGGTGCTAGCTTCGGCTATCAGCTACTGT
GGGTTGTCGTTTGGGCCAACCTGATGGCGATGCTGATTCAGATCCTCTCTGCCAAACTAGGGATTGCCACCGGTAAAAAT
CTGGCGGAGCAGATTCGTGATCACTATCCGCGTCCCGTAGTGTGGTTCTATTGGGTTCAGGCAGAAATTATTGCGATGGC
AACCGACCTGGCGGAATTTATTGGTGCGGCGATCGGTTTTAAACTCATTCTTGGTGTTTCGTTGTTGCAGGGCGCGGTGC
TGACGGGGATCGCGACTTTCCTGATTTTAATGCTGCAACGTCGCGGGCAAAAACCGCTGGAGAAAGTGATTGGCGGGTTA
CTGTTGTTTGTTGCCGCGGCTTACATTGTCGAGTTGATTTTCTCCCAGCCTAACCTGGCGCAGCTGGGTAAAGGAATGGT
GATCCCGAGTTTACCTACTTCGGAGGCGGTCTTCCTGGCAGCAGGCGTGTTAGGGGCGACGATTATGCCGCATGTGATTT
ATTTGCACTCTTCGCTCACTCAGCATTTACATGGCGGTTCGCGTCAACAACGTTATTCCGCCACCAAATGGGATGTGGCT
ATCGCCATGACGATTGCCGGTTTTGTCAATCTGGTGATGATGGCTACAGCTGCGGCGGCGTTCCACTTTTCTGGTCATAC
TGGTGTTGCCGATCTTGATGAGGCTTATCTGACGCTGCAACCGCTGTTAAGCCATGCTGCGGCAACGGTCTTTGGGTTAA
GTCTGGTTGCTGCCGGACTGTCCTCAACGGTGGTGGGGACACTGGCGGGGCAGGTGGTGATGCAGGGATTCATTCGCTTC
CATATCCCGCTGTGGGTGCGTCGTACAGTCACCATGTTGCCGTCATTTATTGTCATTCTGATGGGATTAGATCCGACACG
GATTCTGGTTATGAGTCAGGTGCTGTTAAGTTTTGGTATCGCCCTGGCGCTGGTTCCACTGCTGATTTTCACCAGTGACA
GCAAGTTGATGGGCGATCTGGTGAACAGCAAACGCGTAAAACAGACAGGCTGGGTGATTGTAGTGCTGGTCGTGGCGCTG
AATATCTGGTTGTTGGTGGGGACGGCGCTGGGATTGTAG

Upstream 100 bases:

>100_bases
CTATCAGAGAAATCACCACAATCCATTTAAATGAATTTGATAATCATTCTCGTTTAGCATAGCATGAAACATAGCAAAGG
CTATGTTTTAGAGGCACAAG

Downstream 100 bases:

>100_bases
TTGAATGAGCGTCGCATCTGGCACTATTGGCGGATGCGGCGTAAACGCCTTATCCGCCCTACGCGTTAAAGAGCCGGTTT
GTAGGCCTGATAAGACGCGC

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKN
LAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVA
IAMTIAGFVNLVMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRF
HIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVAL
NIWLLVGTALGL

Sequences:

>Translated_412_residues
MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKN
LAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVA
IAMTIAGFVNLVMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRF
HIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVAL
NIWLLVGTALGL
>Mature_411_residues
TNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNL
AEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLL
LFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAI
AMTIAGFVNLVMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFH
IPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALN
IWLLVGTALGL

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=439, Percent_Identity=31.4350797266515, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI295293178, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI295293175, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI295293173, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI10835169, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI295293171, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI295293169, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI295293167, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=3e-42,
Organism=Escherichia coli, GI1788736, Length=412, Percent_Identity=99.7572815533981, Blast_Score=814, Evalue=0.0,
Organism=Caenorhabditis elegans, GI193210616, Length=432, Percent_Identity=30.3240740740741, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17569473, Length=393, Percent_Identity=30.5343511450382, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71999499, Length=439, Percent_Identity=28.9293849658314, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71993856, Length=221, Percent_Identity=36.6515837104072, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323062, Length=390, Percent_Identity=33.5897435897436, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324450, Length=438, Percent_Identity=29.2237442922374, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321841, Length=418, Percent_Identity=31.1004784688995, Blast_Score=157, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24648607, Length=442, Percent_Identity=30.7692307692308, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI281362176, Length=442, Percent_Identity=30.7692307692308, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24648609, Length=442, Percent_Identity=30.7692307692308, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI45553443, Length=418, Percent_Identity=31.5789473684211, Blast_Score=205, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 44222; Mature: 44091

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWAN
CCCEECCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH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HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA