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The map label for this gene is dsdA

Identifier: 30063773

GI number: 30063773

Start: 2460404

End: 2461732

Strand: Direct

Name: dsdA

Synonym: S2570

Alternate gene names: 30063773

Gene position: 2460404-2461732 (Clockwise)

Preceding gene: 30063771

Following gene: 30063776

Centisome position: 53.49

GC content: 50.56

Gene sequence:

>1329_bases
ATGGAAAACGCTAAAATGAACTCGCTCATCGCCCAGTATCCGTTGGTAAAGGATCTGGTTGCTCTTAAAGAAACCACCTG
GTTTAATCCTAGCACGACCTCATTGGCTGAAGGTTTACCTTATGTTGGCCTGACCGAACAGGATGTTCAGGACGCCCATG
CGCGCTTATCCCGTTTTGCACCCTATCTGGCAAAAGCATTTGCTGAAACAGCTGCCACTGGGGGGATTATTGAATCAGAA
CTGGTTGCCATTCCGGCTATGCAAAAACGGCTGGAAAAGGAATATCAACAACCGATCAGCGGGCAACTCCTACTGAAAAA
AGATAGCCATTTGCCCATTTCCGGCTCTATAAAAGCACGCGGCGGGATTTATGAAGTCCTGGCACATGCAGAAAAACTGG
CTCTGGAAGCGGGGTTGCTGACGCTTGATGATGACTACAGCAAACTGCTTTCTCCGGAGTTTAAACAGTTCTTTAGCCAA
TACAGCATTGCTGTGGGCTCAACCGGAAATCTGGGGTTATCAATCGGCATTATGAGCGCCCGCATTGGCTTTAAGGTGAC
AGTTCATATGTCTGCTGATGCCCGGGCATGGAAAAAAGCGAAACTGCGCAGCCATGGCGTTACGGTCGTGGAATATGAGC
AAGATTATGGTGTTGCCGTCGAGGAAGGACGTAAAGCAGCGCAGTCTGACCCGAACTGTTTCTTTATTGATGACGAAAAT
TCCCGCACGTTGTTCCTTGGGTATTCCGTTGCTGGCCAGCGTCTTAAAGCGCAATTTGCCCAGCAAGGCCGTATCGTCGA
TGCTGATAACCCTCTGTTTGTCTATCTGCCGTGTGGTGTTGGCGGTGGTCCTGGTGGCGTCGCATTCGGGCTTAAACTGG
CGTTTGGCGATCATGTTCACTGCTTTTTTGCCGAACCAACGCACTCCCCTTGTATGTTGTTAGGCGTCCATACAGGATTA
CACGATCAGATTTCTGTTCAGGATATTGGTATCGACAACCTTACCGCAGCGGATGGCCTTGCAGTTGGTCGCGCATCATG
CTTTGTCGGGCGGGCAATGGAGCGTCTGCTGGATGGCTTCTATACCCTTAGCGATCAAACCATGTATGACATGCTTGGCT
GGCTGGCGCAGGAAGAAGGTATTCGTCTTGAACCTTCAGCACTGGCGGGTATGGCCGGACCTCAGCGCGTGTGTGCATCA
GTAAGTTACCAACAGATGCACGGTTTCAGCGCAGAACAATTGCGTAATGCCACTCATCTGGTGTGGGCGACGGGAGGTGG
AATGGTGCCGGAAGAAGAGATGAATCAATATCTGGCAAAAGGCCGTTAA

Upstream 100 bases:

>100_bases
CATTTAAATACTATACGACAGCGACATTTATCGCTTCAGTCGTCGCTCTGGCGGGCACATTCCTGCTGTCATTTATCATC
TAAGCGCAAAGAGACGTACT

Downstream 100 bases:

>100_bases
TAACGTTTCAACGCAACATCGCAATCCTTTCCCTGGGTGAGCGATGCTGCCGATGGCGCAGACTTAAGATCCCCGGTCTT
ACCCGCTATAACCCCCTCCT

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MENAKMNSLIAQYPLVKDLVALKETTWFNPSTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFAETAATGGIIESE
LVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASCFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR

Sequences:

>Translated_442_residues
MENAKMNSLIAQYPLVKDLVALKETTWFNPSTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFAETAATGGIIESE
LVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASCFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR
>Mature_442_residues
MENAKMNSLIAQYPLVKDLVALKETTWFNPSTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFAETAATGGIIESE
LVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASCFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=442, Percent_Identity=99.0950226244344, Blast_Score=902, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 47921; Mature: 47921

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENAKMNSLIAQYPLVKDLVALKETTWFNPSTTSLAEGLPYVGLTEQDVQDAHARLSRFA
CCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
PYLAKAFAETAATGGIIESELVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKAR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
GGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSA
CCHHHHHHHHHHHHHHHCEEEECCCHHHHCCHHHHHHHHHHEEEECCCCCCEEEEEEEEE
RIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
ECCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHCCCCCEEEEECCC
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCEEE
CFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASCFVGRAMERLLDGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQMHGFSAEQLRNATHL
EECCCCHHHHHHHHHHHCCCCEECHHHHHCCCCHHHHHHHCCHHHHCCCCHHHHCCCEEE
VWATGGGMVPEEEMNQYLAKGR
EEECCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MENAKMNSLIAQYPLVKDLVALKETTWFNPSTTSLAEGLPYVGLTEQDVQDAHARLSRFA
CCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
PYLAKAFAETAATGGIIESELVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKAR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
GGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSA
CCHHHHHHHHHHHHHHHCEEEECCCHHHHCCHHHHHHHHHHEEEECCCCCCEEEEEEEEE
RIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
ECCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHCCCCCEEEEECCC
SRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCEEE
CFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASCFVGRAMERLLDGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQMHGFSAEQLRNATHL
EECCCCHHHHHHHHHHHCCCCEECHHHHHCCCCHHHHHHHCCHHHHCCCCHHHHCCCEEE
VWATGGGMVPEEEMNQYLAKGR
EEECCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA