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The map label for this gene is ubiG

Identifier: 30063665

GI number: 30063665

Start: 2334464

End: 2335186

Strand: Direct

Name: ubiG

Synonym: S2445

Alternate gene names: 30063665

Gene position: 2334464-2335186 (Clockwise)

Preceding gene: 30063656

Following gene: 30063666

Centisome position: 50.76

GC content: 54.36

Gene sequence:

>723_bases
ATGAATGCCGAAAAATCGCCGGAAAACCATAACGTAGACCACGAAGAGATCGCTAAATTTGAAGCCGTCGCCTCCCGCTG
GTGGGATCTTGAAGGTGAGTTCAAACCGTTGCACCGCATTAACCCGCTGCGTCTGGGCTATATTGCCGAGCGTGCTGGCG
GTTTATTTGGCAAAAAGGTGCTCGATGTCGGTTGTGGCGGCGGCATTCTGGCCGAGAGTATGGCGCGCGAAGGCGCGACG
GTGACCGGTCTGGATATGGGCTTTGAGCCATTGCAGGTGGCAAAGCTGCACGCGCTGGAAAGCGGCATTCAGGTGGATTA
CGTGCAGGAAACCGTGGAAGAGCACGCGGCAAAACATGCCGGGCAGTATGATGTGGTGACCTGCATGGAGATGCTGGAGC
ACGTACCCGATCCGCAGTCAGTGGTCAGAGCCTGTGCGCAACTGGTGAAACCAGGCGGCGATGTCTTTTTCTCGACGCTT
AACCGCAACGGCAAGTCATGGCTGATGGCGGTGGTTGGCGCGGAATATATTTTGCGCATGGTGCCCAAAGGTACGCATGA
TGTGAAGAAGTTTATTAAACCGGCAGAGCTGCTTGGCTGGGTGGATCAGACCAGTTTAAAAGAGCGACATATAACCGGGC
TACATTACAACCCGATCACTAATTCCTTTAAGCTCGGCCCCGGCGTGGATGTGAACTATATGCTGCACACGCAGAATAAG
TGA

Upstream 100 bases:

>100_bases
TATAACACAGCCGCGCAGTTTGAGGTAAACCTATACGCTTTATTCACATCCAATGCCTGATATACTCGTTTGTCTTGCCA
ATTACGGAGTAGAAGTGCCA

Downstream 100 bases:

>100_bases
GGTTGATGTTTGGCCGCGCCAATGCCTGATGCGACGCTTGCAGCGTCTTATCAGGCCTACAAATGCTCTCCGTAGGCCAG
ATAAGGCGTTTACGCCGCAT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNSFKLGPGVDVNYMLHTQNK

Sequences:

>Translated_240_residues
MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNSFKLGPGVDVNYMLHTQNK
>Mature_240_residues
MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNSFKLGPGVDVNYMLHTQNK

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=241, Percent_Identity=33.6099585062241, Blast_Score=157, Evalue=6e-39,
Organism=Escherichia coli, GI1788564, Length=240, Percent_Identity=99.1666666666667, Blast_Score=496, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI115533050, Length=239, Percent_Identity=31.3807531380753, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6324476, Length=250, Percent_Identity=30.4, Blast_Score=127, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281365311, Length=229, Percent_Identity=33.6244541484716, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24585589, Length=227, Percent_Identity=34.3612334801762, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26572; Mature: 26572

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCHHHHHH
LDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHA
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
VPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNSFKLGPGVDVNYMLHTQNK
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEECCCCCCEECCCCCCEEEEEEECCC
>Mature Secondary Structure
MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCHHHHHH
LDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHA
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
VPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNSFKLGPGVDVNYMLHTQNK
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEECCCCCCEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA