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The map label for this gene is phpB

Identifier: 30062173

GI number: 30062173

Start: 676845

End: 677456

Strand: Direct

Name: phpB

Synonym: S0665

Alternate gene names: 30062173

Gene position: 676845-677456 (Clockwise)

Preceding gene: 30062172

Following gene: 30062174

Centisome position: 14.72

GC content: 50.65

Gene sequence:

>612_bases
ATGCGACTGTGGTTAATTCGTCATGGCGAAACACAAGCGAATGTCGATGGTCTGTACAGCGGTCATGCGCCCACACCCCT
GACCGCACGCGGTATTGAGCAAGCGCAAAATCTGCATACACTGCTAGATGATGTTTCCTTTGACTTGGTTTTATGCAGTG
AACTGGAACGGGCACAGCATACCGCGCGACTGGTTCTCAGTGACCGCCAGCTCCCCGTTCATATCATCCCTGAACTCAAC
GAAATGTTTTTTGGCGACTGGGAGATGCGACATCATCGCGACCTCATGCAAGAAGATGCCGAAAACTATAGCGCGTGGTG
CAATGACTGGCAGCATGCTATCCCCACGAACGGTGAAGGATTTCAGGCATTTTCGCAACGTGTGGAACGCTTTATCGCAA
GGCTTAGTGAATATCAGCACTATCAGAATATTTTAATCGTCAGCCATCAGGGCGTACTGAGTCTGTTAATTGCTCGTTTA
ATTGGCATGCCTGCCGAGTCTATGTGGCATTTTCGCGTTGACCAGGGGTGTTGGAGCGCCATTGATATCAACCAAAAATT
CGCGACGCTACGCGTCCTCAATAGCCGTGCCATCGGGGTCGAGAACGCATGA

Upstream 100 bases:

>100_bases
AAAACGGTGAATCGTGTGAGGATTTATTGCCGGAACCGGTATTGACTTACATTAACCAACAAGGCTTGTATCGCTGATAC
CTGTCGTTACGGAGGGCATG

Downstream 100 bases:

>100_bases
CTTTTCTGTTTTTTTACGGGTAAGCCGCAACGACCATTGACAGCCCCGGGCAGGCTGATATTCTCCGCAGCCAGACTTTT
TCCGCCAGACACGACTTTGT

Product: alpha-ribazole phosphatase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDDVSFDLVLCSELERAQHTARLVLSDRQLPVHIIPELN
EMFFGDWEMRHHRDLMQEDAENYSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARL
IGMPAESMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA

Sequences:

>Translated_203_residues
MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDDVSFDLVLCSELERAQHTARLVLSDRQLPVHIIPELN
EMFFGDWEMRHHRDLMQEDAENYSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARL
IGMPAESMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA
>Mature_203_residues
MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDDVSFDLVLCSELERAQHTARLVLSDRQLPVHIIPELN
EMFFGDWEMRHHRDLMQEDAENYSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARL
IGMPAESMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=203, Percent_Identity=96.551724137931, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1790856, Length=187, Percent_Identity=26.2032085561497, Blast_Score=77, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324857, Length=217, Percent_Identity=26.2672811059908, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 23386; Mature: 23386

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDDVSFDLVLCSELERAQH
CEEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TARLVLSDRQLPVHIIPELNEMFFGDWEMRHHRDLMQEDAENYSAWCNDWQHAIPTNGEG
HHHHHHCCCCCCEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCH
FQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARLIGMPAESMWHFRVDQGCWSA
HHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHCCCHHHHEEEEECCCCCCE
IDINQKFATLRVLNSRAIGVENA
EECCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDDVSFDLVLCSELERAQH
CEEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TARLVLSDRQLPVHIIPELNEMFFGDWEMRHHRDLMQEDAENYSAWCNDWQHAIPTNGEG
HHHHHHCCCCCCEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCH
FQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARLIGMPAESMWHFRVDQGCWSA
HHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHCCCHHHHEEEEECCCCCCE
IDINQKFATLRVLNSRAIGVENA
EECCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]