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The map label for this gene is farR

Identifier: 30062107

GI number: 30062107

Start: 587457

End: 588401

Strand: Direct

Name: farR

Synonym: S0580

Alternate gene names: 30062107

Gene position: 587457-588401 (Clockwise)

Preceding gene: 30062092

Following gene: 30062117

Centisome position: 12.77

GC content: 48.25

Gene sequence:

>945_bases
ATGGGACACAAACCCTTATACCGACAGATTGCTGATCGCATTCGTGAGCAAATTGCGCGTGGCGAGCTTAAACCTGGCGA
TGCGTTACCTACCGAATCGGCATTACAAACAGAGTTTGGCGTCAGCCGGGTTACGGTGCGTCAGGCTTTGCGCCAGTTAG
TCGAGCAACAGATCCTCGAAAGCATTCAGGGCAGCGGGACTTACGTCAAAGAAGAGCGGGTCAATTACGATATTTTTCAG
TTAACCAGTTTTGATGAAAAACTGTCGGACCGTCACGTCGATACACACAGTGAAGTTCTGATATTTGAAGTGATTCCGGC
TGACGATTTTCTTCAGCAACAGCTACAAATCACCGTGCAGGATCGTGTGTGGCATGTGAAGCGCGTGCGCTATCGCAAGC
AAAAGCCAATGGCGCTGGAAGAAACCTGGATGCCGCTTGCGTTGTTCCCGGATCTCACCTGGCAGGTCATGGAAAATTCG
AAATATCACTTTATTGAAGAAGTGAAGAAGATGGTTATCGATCGTAGCGAACAGGAAATCATTCCTCTGATGCCAACCGA
AGAGATGAGCCGTCTGCTTAATATCAGCCAGACAAAGCCGATTCTTGAAAAAGTATCGCGTGGATATTTAGTTGATGGTC
GGGTGTTTGAATATAGCCGCAACGCTTTTAATACCGATGACTATAAATTTACCCTGATAGCGCAGCCGAAAATCATCGCG
ATAAGCACAAAAAGGCCATCATACGATGGCCAACCATGTGGAAACCGACAGCCCTTCGCCATTCCTGTAGAGGGAAGCGG
CGAGGGCTATTTCTTATTACAGATATTTATTTCAGAACAGTTTTCAGTGCTTCACCGATATCCGCCAGGCTGCGAACGGT
TTTCACGCCTGCGGCTTCCAGAGCAGCGAATTTCTCATCCGCAGTCCCTTTCCCACCGGCAATGA

Upstream 100 bases:

>100_bases
AATTTCACTTGATTGAAATTATTTGCATTTTATTTGTATTATTTACAGGATGAGTTTATCGGGCATAATGGCTAAATTCG
TATTAATGAGATGCTAAATA

Downstream 100 bases:

>100_bases
TCGCACCCGCGTGGCCCATACGTTTGCCTTTCGGCGCAGTCACACCAGCGATGTAACCCACAACTGGCTTGGTAACATGC
TCTTTGATGTACGCTGCCGC

Product: DNA-binding transcriptional repressor MngR

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQ
LTSFDEKLSDRHVDTHSEVLIFEVIPADDFLQQQLQITVQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENS
KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTLIAQPKIIA
ISTKRPSYDGQPCGNRQPFAIPVEGSGEGYFLLQIFISEQFSVLHRYPPGCERFSRLRLPEQRISHPQSLSHRQ

Sequences:

>Translated_314_residues
MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQ
LTSFDEKLSDRHVDTHSEVLIFEVIPADDFLQQQLQITVQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENS
KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTLIAQPKIIA
ISTKRPSYDGQPCGNRQPFAIPVEGSGEGYFLLQIFISEQFSVLHRYPPGCERFSRLRLPEQRISHPQSLSHRQ
>Mature_313_residues
GHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQL
TSFDEKLSDRHVDTHSEVLIFEVIPADDFLQQQLQITVQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENSK
YHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTLIAQPKIIAI
STKRPSYDGQPCGNRQPFAIPVEGSGEGYFLLQIFISEQFSVLHRYPPGCERFSRLRLPEQRISHPQSLSHRQ

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=237, Percent_Identity=99.1561181434599, Blast_Score=479, Evalue=1e-137,
Organism=Escherichia coli, GI1790118, Length=224, Percent_Identity=31.25, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87082252, Length=227, Percent_Identity=26.431718061674, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788418, Length=232, Percent_Identity=25.4310344827586, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790540, Length=230, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 36694; Mature: 36563

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILE
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
SIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIFEVIPADDFLQQQLQITVQ
HHCCCCCEEECCCCCCEEEEECCHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHH
DRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENSKYHFIEEVKKMVIDRSEQEI
HHHHHHHHHHHHHCCCCCHHHCCCCEEECCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCE
IPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTLIAQPKIIA
ECCCCHHHHHHHHCCCCCHHHHHHHHCCEEECCEEEEECCCCCCCCCEEEEEEECCEEEE
ISTKRPSYDGQPCGNRQPFAIPVEGSGEGYFLLQIFISEQFSVLHRYPPGCERFSRLRLP
EECCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHCCCCCHHHHHHCCCC
EQRISHPQSLSHRQ
HHHCCCCCCCCCCC
>Mature Secondary Structure 
GHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILE
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
SIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIFEVIPADDFLQQQLQITVQ
HHCCCCCEEECCCCCCEEEEECCHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHH
DRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENSKYHFIEEVKKMVIDRSEQEI
HHHHHHHHHHHHHCCCCCHHHCCCCEEECCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCE
IPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTLIAQPKIIA
ECCCCHHHHHHHHCCCCCHHHHHHHHCCEEECCEEEEECCCCCCCCCEEEEEEECCEEEE
ISTKRPSYDGQPCGNRQPFAIPVEGSGEGYFLLQIFISEQFSVLHRYPPGCERFSRLRLP
EECCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHCCCCCHHHHHHCCCC
EQRISHPQSLSHRQ
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]