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The map label for this gene is aslA [H]

Identifier: 29350039

GI number: 29350039

Start: 6062271

End: 6063833

Strand: Reverse

Name: aslA [H]

Synonym: BT_4631

Alternate gene names: 29350039

Gene position: 6063833-6062271 (Counterclockwise)

Preceding gene: 29350040

Following gene: 29350038

Centisome position: 96.86

GC content: 42.99

Gene sequence:

>1563_bases
ATGATGAATAAAAGATCCCTCAATCTGCTGCCTTGTGTCGCAGTTCTATGTTCTTGTTCTTTGCCCGCGTATGCCGGGCA
AAGTTCAAAAAAAGAAAAAAAAACAAAACCTAATGTTATTATCATTCTCGCAGACGATTTAGGTTATGGTGATCTTGAAT
GTTATGGTACCACACGTGTACATACCCCCAATGTAAATCGGTTGGCTTCTGAAGGTATACGGTTTACCAATGTACATGCT
ACCGCTTCTACCAGTACTCCTTCCCGCTATGCTTTGCTGACCGGAGAATATGCATGGAGAAAGAAAGGTACCGGAGTAGC
TGCAGGTAATGCAGGCATGATAATTCGACCAGAACAATATACTATAGCCGATATGTTTAAATCGGCAGACTATACCACCG
GAGCTATTGGTAAATGGCATCTAGGATTAGGTGACAAAACGGGTACACAAGACTGGAACGGGACAATATCTCCTGCACTC
AAAGATATAGGATTCGACTATTCTTATATCATGGCTGCTACTGCAGACCGTGTTCCTTGCATTTATATTGAAAACGGTAA
AGTAGCCGACTATGATTCCACCGCTCCTATTGAAGTCAGTTATCAGAAACCATTTGAAGGTGAGCCGACAGGAAGAAAGA
ATCCTGAATTGCTTTATAATCTCAAGCCAAGCCACGGACACGACATGGCAATCGTAAACGGTATCTCGCGCATCGGATAC
ATGAAAGGAGGAGGTAAAGCTTTGTGGAAAGATGAAAATATAGCAGACACCATCACCAGTCATGCCATCCGTTTCATTGA
AGAAAACAAAGAGCGGCCTTTCTTTCTTTATTTTGCGACCAATGATGTACATGTTCCCCGCTTCCCACACGAACGTTTCA
GAGGTAAAAACCCGATGGGATTACGAGGTGATGCCATTGTACAGTTTGACTGGAGCGTGGGAGAAATCATGAAAACGTTA
GACCGGCTGGGATTGACTGAAAACACACTCATTATTCTATCCAGCGATAACGGTCCGGTACTGGATGATGGTTATGATGA
CAAAGCCGTTGAGCTTGCTGGCAGTCATAAGCCGGGTGGTCCTTTCCGTGGTGGAAAATACAGTGCCTTCGAAGCGGGAA
CATGTGTTCCGGCCATCGTACGCTATCCGGCACAGGTGAAAAAGAACCAAACTTTAAACACATTGCTAAGCCAAATAGAC
TGGATCCAATCATTGGCTTCTCTAGTAAATGTCACTATTCCCCAAAGTAAAGCTCCGGACAGTCAAAATCATTTAGACAG
TTGGTTAGGAAAAAGTAAAAAAGATCGTCCTTGGGTTATCGAGGAATCTAATATTCTGGCATTATCCGTACGCAAAGGAA
AATGGAAATATATCGAACCTTCCAATGGTTCCCCCATGATCACTTGGGGTCCGAAAATAGAAACAGGATATGCACCTTAT
GATCAGCTGTTCGATATGAATAAGTCCGAGTTTGAAAGCGAAAATCTGGCTCCGAAATATCCAGCCATAGTAAAAGAAAT
GAAAGATATATTGGTGCAGGAAAGAGCAAAAGGGAAAAAGTGA

Upstream 100 bases:

>100_bases
AACTGTCCTCCTGCCGCCATTCGCGAATTGACTGTTTACGGATTAGAAGGTAATAATTAAAAATCAGTATTATACTCAAA
ACCTTATTTGATTTAAACAC

Downstream 100 bases:

>100_bases
CATTTATTGAAACAACAAAATATATGGCTTCACCAAAATAAACAAAAACCTTTCTATTTATTTTCAATAGGCTAATTATA
AAATTCAAAAAGGTGTGTCA

Product: putative arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MMNKRSLNLLPCVAVLCSCSLPAYAGQSSKKEKKTKPNVIIILADDLGYGDLECYGTTRVHTPNVNRLASEGIRFTNVHA
TASTSTPSRYALLTGEYAWRKKGTGVAAGNAGMIIRPEQYTIADMFKSADYTTGAIGKWHLGLGDKTGTQDWNGTISPAL
KDIGFDYSYIMAATADRVPCIYIENGKVADYDSTAPIEVSYQKPFEGEPTGRKNPELLYNLKPSHGHDMAIVNGISRIGY
MKGGGKALWKDENIADTITSHAIRFIEENKERPFFLYFATNDVHVPRFPHERFRGKNPMGLRGDAIVQFDWSVGEIMKTL
DRLGLTENTLIILSSDNGPVLDDGYDDKAVELAGSHKPGGPFRGGKYSAFEAGTCVPAIVRYPAQVKKNQTLNTLLSQID
WIQSLASLVNVTIPQSKAPDSQNHLDSWLGKSKKDRPWVIEESNILALSVRKGKWKYIEPSNGSPMITWGPKIETGYAPY
DQLFDMNKSEFESENLAPKYPAIVKEMKDILVQERAKGKK

Sequences:

>Translated_520_residues
MMNKRSLNLLPCVAVLCSCSLPAYAGQSSKKEKKTKPNVIIILADDLGYGDLECYGTTRVHTPNVNRLASEGIRFTNVHA
TASTSTPSRYALLTGEYAWRKKGTGVAAGNAGMIIRPEQYTIADMFKSADYTTGAIGKWHLGLGDKTGTQDWNGTISPAL
KDIGFDYSYIMAATADRVPCIYIENGKVADYDSTAPIEVSYQKPFEGEPTGRKNPELLYNLKPSHGHDMAIVNGISRIGY
MKGGGKALWKDENIADTITSHAIRFIEENKERPFFLYFATNDVHVPRFPHERFRGKNPMGLRGDAIVQFDWSVGEIMKTL
DRLGLTENTLIILSSDNGPVLDDGYDDKAVELAGSHKPGGPFRGGKYSAFEAGTCVPAIVRYPAQVKKNQTLNTLLSQID
WIQSLASLVNVTIPQSKAPDSQNHLDSWLGKSKKDRPWVIEESNILALSVRKGKWKYIEPSNGSPMITWGPKIETGYAPY
DQLFDMNKSEFESENLAPKYPAIVKEMKDILVQERAKGKK
>Mature_520_residues
MMNKRSLNLLPCVAVLCSCSLPAYAGQSSKKEKKTKPNVIIILADDLGYGDLECYGTTRVHTPNVNRLASEGIRFTNVHA
TASTSTPSRYALLTGEYAWRKKGTGVAAGNAGMIIRPEQYTIADMFKSADYTTGAIGKWHLGLGDKTGTQDWNGTISPAL
KDIGFDYSYIMAATADRVPCIYIENGKVADYDSTAPIEVSYQKPFEGEPTGRKNPELLYNLKPSHGHDMAIVNGISRIGY
MKGGGKALWKDENIADTITSHAIRFIEENKERPFFLYFATNDVHVPRFPHERFRGKNPMGLRGDAIVQFDWSVGEIMKTL
DRLGLTENTLIILSSDNGPVLDDGYDDKAVELAGSHKPGGPFRGGKYSAFEAGTCVPAIVRYPAQVKKNQTLNTLLSQID
WIQSLASLVNVTIPQSKAPDSQNHLDSWLGKSKKDRPWVIEESNILALSVRKGKWKYIEPSNGSPMITWGPKIETGYAPY
DQLFDMNKSEFESENLAPKYPAIVKEMKDILVQERAKGKK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI146229331, Length=477, Percent_Identity=29.1404612159329, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI146229329, Length=477, Percent_Identity=29.1404612159329, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI6005990, Length=477, Percent_Identity=29.1404612159329, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI146229324, Length=477, Percent_Identity=29.1404612159329, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4503899, Length=416, Percent_Identity=29.5673076923077, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI45430057, Length=517, Percent_Identity=27.4661508704062, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI71852584, Length=425, Percent_Identity=27.5294117647059, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI71852586, Length=315, Percent_Identity=29.2063492063492, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI53831991, Length=281, Percent_Identity=28.8256227758007, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI58743319, Length=118, Percent_Identity=44.0677966101695, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI31742482, Length=183, Percent_Identity=35.5191256830601, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI157266309, Length=162, Percent_Identity=35.1851851851852, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI146229327, Length=393, Percent_Identity=25.6997455470738, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI59797060, Length=133, Percent_Identity=34.5864661654135, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI38569405, Length=118, Percent_Identity=37.2881355932203, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI38569407, Length=115, Percent_Identity=37.3913043478261, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI109389362, Length=120, Percent_Identity=34.1666666666667, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790233, Length=377, Percent_Identity=26.2599469496021, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790112, Length=114, Percent_Identity=35.0877192982456, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559078, Length=285, Percent_Identity=29.1228070175439, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24666175, Length=400, Percent_Identity=25.25, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281366397, Length=456, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281366395, Length=456, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24666163, Length=456, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24666109, Length=466, Percent_Identity=25.1072961373391, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363223, Length=413, Percent_Identity=25.4237288135593, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 57545; Mature: 57545

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNKRSLNLLPCVAVLCSCSLPAYAGQSSKKEKKTKPNVIIILADDLGYGDLECYGTTRV
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCEEEEECCEE
HTPNVNRLASEGIRFTNVHATASTSTPSRYALLTGEYAWRKKGTGVAAGNAGMIIRPEQY
ECCCHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCHHECCCCCEEEECCCCEEECCCCC
TIADMFKSADYTTGAIGKWHLGLGDKTGTQDWNGTISPALKDIGFDYSYIMAATADRVPC
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCE
IYIENGKVADYDSTAPIEVSYQKPFEGEPTGRKNPELLYNLKPSHGHDMAIVNGISRIGY
EEECCCEEECCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCE
MKGGGKALWKDENIADTITSHAIRFIEENKERPFFLYFATNDVHVPRFPHERFRGKNPMG
ECCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECCCCCHHHHCCCCCCC
LRGDAIVQFDWSVGEIMKTLDRLGLTENTLIILSSDNGPVLDDGYDDKAVELAGSHKPGG
CCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCC
PFRGGKYSAFEAGTCVPAIVRYPAQVKKNQTLNTLLSQIDWIQSLASLVNVTIPQSKAPD
CCCCCCCCCCCCCCCHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCC
SQNHLDSWLGKSKKDRPWVIEESNILALSVRKGKWKYIEPSNGSPMITWGPKIETGYAPY
CHHHHHHHHCCCCCCCCEEEECCCEEEEEEECCCEEEECCCCCCEEEEECCCCCCCCCCH
DQLFDMNKSEFESENLAPKYPAIVKEMKDILVQERAKGKK
HHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMNKRSLNLLPCVAVLCSCSLPAYAGQSSKKEKKTKPNVIIILADDLGYGDLECYGTTRV
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCEEEEECCEE
HTPNVNRLASEGIRFTNVHATASTSTPSRYALLTGEYAWRKKGTGVAAGNAGMIIRPEQY
ECCCHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCHHECCCCCEEEECCCCEEECCCCC
TIADMFKSADYTTGAIGKWHLGLGDKTGTQDWNGTISPALKDIGFDYSYIMAATADRVPC
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCE
IYIENGKVADYDSTAPIEVSYQKPFEGEPTGRKNPELLYNLKPSHGHDMAIVNGISRIGY
EEECCCEEECCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCE
MKGGGKALWKDENIADTITSHAIRFIEENKERPFFLYFATNDVHVPRFPHERFRGKNPMG
ECCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECCCCCHHHHCCCCCCC
LRGDAIVQFDWSVGEIMKTLDRLGLTENTLIILSSDNGPVLDDGYDDKAVELAGSHKPGG
CCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCC
PFRGGKYSAFEAGTCVPAIVRYPAQVKKNQTLNTLLSQIDWIQSLASLVNVTIPQSKAPD
CCCCCCCCCCCCCCCHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCC
SQNHLDSWLGKSKKDRPWVIEESNILALSVRKGKWKYIEPSNGSPMITWGPKIETGYAPY
CHHHHHHHHCCCCCCCCEEEECCCEEEEEEECCCEEEECCCCCCEEEEECCCCCCCCCCH
DQLFDMNKSEFESENLAPKYPAIVKEMKDILVQERAKGKK
HHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]