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The map label for this gene is tyrA [C]

Identifier: 29349341

GI number: 29349341

Start: 5107036

End: 5107809

Strand: Reverse

Name: tyrA [C]

Synonym: BT_3933

Alternate gene names: 29349341

Gene position: 5107809-5107036 (Counterclockwise)

Preceding gene: 29349342

Following gene: 29349340

Centisome position: 81.59

GC content: 47.8

Gene sequence:

>774_bases
ATGAGAATATTAATCCTCGGAGCCGGTAAAATGGGTTCCTTCTTTACGGATATACTGAGTTTTCAGCACGAGACGGCCGT
GTTTGACGTCAACCCGCACCAGTTGCGTTTCGTGTATAACACGTATCGTTTCACCACACTGGAGGAAATCAAAGAATTCG
AACCCGAACTGGTCATCAATGCCGTCACCGTAAAATACACGCTGGATGCTTTCCGCAAGGTATTGCCTGTGCTGCCCAAA
GACTGTATCATCAGTGACATCGCTTCCGTAAAGACAGGACTGAAGAAGTTCTACGAAGAAAGCGGATTCCGCTACGTTTC
CAGTCACCCTATGTTCGGACCGACGTTTGCCAGTCTCAGCAATCTGAGCAGCGAGAATGCGATTATCATCAGCGAAGGAG
ATCATTTGGGAAAGATTTTCTTCAAAGACCTTTACCAGACGCTGCGCCTGAACATCTTCGAATATACGTTCGACGAACAT
GATGAAACGGTGGCATACTCGCTCTCCATCCCATTCGTTTCGACTTTCGTATTTGCTGCCGTGATGAAGCATCAGGAAGC
TCCGGGAACAACTTTCAAGAAGCACATGGCTATCGCAAAGGGGCTGCTGAGCGAAGATGACTACCTGCTGCAGGAAATCC
TGTTCAACCCACGCACCCCGGGACAAGTGGCCAATATCCGTACAGAGCTGAAGAATCTTCTCGAAATCATCGAAAAGAAA
GATGCGGAAGGTATGAAAGCCTACCTCACCAAGATTCGGGAAAAGATCAAGTAA

Upstream 100 bases:

>100_bases
GAATAGAGATAGAATCGACTTTTTAGTCACCCCAATGTGAGATACTATTAACTTTTAGAGAGACTATTGACTTTTGAGAA
ACTCCCCAATAATAATAGAT

Downstream 100 bases:

>100_bases
ATCATCCTCTCCTTCGATAAGATTTAACCATCCCCTGCAAGAAAGTTCTTTGCAGGGGATTTTTTTATATGTACCTTTGT
ATCCGCAAAAACGGAATCAC

Product: chorismate mutase/prephenate dehydratase (tyrA)

Products: 4-hydroxyphenylpyruvate; CO2; NADH

Alternate protein names: Prephenate Dehydrogenase; Prephenate Dehydrogenase Family Protein

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRILILGAGKMGSFFTDILSFQHETAVFDVNPHQLRFVYNTYRFTTLEEIKEFEPELVINAVTVKYTLDAFRKVLPVLPK
DCIISDIASVKTGLKKFYEESGFRYVSSHPMFGPTFASLSNLSSENAIIISEGDHLGKIFFKDLYQTLRLNIFEYTFDEH
DETVAYSLSIPFVSTFVFAAVMKHQEAPGTTFKKHMAIAKGLLSEDDYLLQEILFNPRTPGQVANIRTELKNLLEIIEKK
DAEGMKAYLTKIREKIK

Sequences:

>Translated_257_residues
MRILILGAGKMGSFFTDILSFQHETAVFDVNPHQLRFVYNTYRFTTLEEIKEFEPELVINAVTVKYTLDAFRKVLPVLPK
DCIISDIASVKTGLKKFYEESGFRYVSSHPMFGPTFASLSNLSSENAIIISEGDHLGKIFFKDLYQTLRLNIFEYTFDEH
DETVAYSLSIPFVSTFVFAAVMKHQEAPGTTFKKHMAIAKGLLSEDDYLLQEILFNPRTPGQVANIRTELKNLLEIIEKK
DAEGMKAYLTKIREKIK
>Mature_257_residues
MRILILGAGKMGSFFTDILSFQHETAVFDVNPHQLRFVYNTYRFTTLEEIKEFEPELVINAVTVKYTLDAFRKVLPVLPK
DCIISDIASVKTGLKKFYEESGFRYVSSHPMFGPTFASLSNLSSENAIIISEGDHLGKIFFKDLYQTLRLNIFEYTFDEH
DETVAYSLSIPFVSTFVFAAVMKHQEAPGTTFKKHMAIAKGLLSEDDYLLQEILFNPRTPGQVANIRTELKNLLEIIEKK
DAEGMKAYLTKIREKIK

Specific function: Tyrosine biosynthesis [C]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.3.1.12; 5.4.99.5

Molecular weight: Translated: 29388; Mature: 29388

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILILGAGKMGSFFTDILSFQHETAVFDVNPHQLRFVYNTYRFTTLEEIKEFEPELVIN
CEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCEEE
AVTVKYTLDAFRKVLPVLPKDCIISDIASVKTGLKKFYEESGFRYVSSHPMFGPTFASLS
EHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHH
NLSSENAIIISEGDHLGKIFFKDLYQTLRLNIFEYTFDEHDETVAYSLSIPFVSTFVFAA
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECHHHHHHHHHH
VMKHQEAPGTTFKKHMAIAKGLLSEDDYLLQEILFNPRTPGQVANIRTELKNLLEIIEKK
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
DAEGMKAYLTKIREKIK
CCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRILILGAGKMGSFFTDILSFQHETAVFDVNPHQLRFVYNTYRFTTLEEIKEFEPELVIN
CEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCEEE
AVTVKYTLDAFRKVLPVLPKDCIISDIASVKTGLKKFYEESGFRYVSSHPMFGPTFASLS
EHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHH
NLSSENAIIISEGDHLGKIFFKDLYQTLRLNIFEYTFDEHDETVAYSLSIPFVSTFVFAA
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEECHHHHHHHHHH
VMKHQEAPGTTFKKHMAIAKGLLSEDDYLLQEILFNPRTPGQVANIRTELKNLLEIIEKK
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
DAEGMKAYLTKIREKIK
CCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: prephenate; NAD+

Specific reaction: prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA