Click here to switch to the map view.

The map label for this gene is ftsZ [H]

Identifier: 29348853

GI number: 29348853

Start: 4436513

End: 4437820

Strand: Reverse

Name: ftsZ [H]

Synonym: BT_3444

Alternate gene names: 29348853

Gene position: 4437820-4436513 (Counterclockwise)

Preceding gene: 29348854

Following gene: 29348852

Centisome position: 70.89

GC content: 51.38

Gene sequence:

>1308_bases
ATGGACGAGATAGTACAATTCGATTTCCCGACCGACTCACCGAAAATCATCAAAGTGATTGGTGTAGGTGGCGGTGGCGG
TAACGCTGTGAACCACATGTACCGGGAAGGCATACATGACGTAACGTTCGTTCTCTGCAACACGGACAACCAGGCATTGG
CCGAGTCACCCGTTCCGGTGAAACTGCAACTGGGCCGTAGCATCACACAAGGACTTGGAGCCGGCAACCGTCCCGAACGG
GCACGCGACGCCGCCGAAGAAAGTATTGACGATATCAAAGAACAGCTGAACGACGGCACCAAGATGGTATTCATCACTGC
CGGAATGGGAGGAGGAACCGGAACCGGAGCCGCCCCTGTCATCGCCCGCATTGCGAAGGAGATGGATATTCTGACAGTAG
GTATTGTCACCATTCCATTTATTTTCGAAGGAGAAAAGAAAATCATTCAGGCACTGGACGGCGTCGAACGTATCGCCCAG
CACGTAGATGCCCTGCTGGTCATCAACAACGAGCGCCTGCGCGAAATATATGCCGACCTTACCTTCATGAATGCTTTCGG
CAAGGCCGATGATACGCTTTCCATCGCTGCAAAGAGTATCGCCGAGATTATCACCATGCGTGGTACGGTGAATCTGGACT
TTGCCGATGTGAAGACCATCCTGAAAGACGGTGGTGTAGCCATCATGAGTACCGGATTCGGAGAAGGCGAGAACCGTGTC
ACCAAAGCTATCGATGATGCCCTCCACTCTCCGTTGCTGAACAACAACGACATCTTCAACGCTAAAAAGGTGATGTTGAA
CGTATCCTTCTGTCCCACGTCCGAACTGATGATGGAAGAAATGAACGAGATACACGAGTTCATGAGCAAGTTCCGCGAAG
GTGTGGAAGTAATCTGGGGTGTCGCCGTAGACAACTCTCTGGACACCAAAGTAAAGATCACCGTACTCGCCACCGGATTT
GGTGTAGAAGACGTGCCCGGTATGGACACACTGCACGAAGCCCGCAGCCAGGAGGAAGAAGAACGCCAGTTGCAGCTTGA
AGAAGAGAAGGAGAAGAATAAAGAGCGTATCCGCAAGGCATACGGTGAAAGTGCCGGCATCGGAAAGAAAAGCCTGCGCA
GCCGTCGCCATATCTATATCTTCAATACCGAAGATTTGGACAACGACGACATCATCGCCATGATAGAGGAATCTCCTACT
TACACGCGCGATAAAACGAAGCTGTTGAAGATCAAGACGAAAGCGGCTCTTGAAGAGGAAGTTGCCATGGAAGAGGCTAC
GGACAATGACGGAGTAATCACTTTCTAG

Upstream 100 bases:

>100_bases
AGAGAGAAGCCGGTCCCAGTTGGATTCAACGCAAGATCGACTCCCTGACCAAGGAAATCTTCTCTGACGACGATATGAAA
TAAATTCAAAATTCAATAAT

Downstream 100 bases:

>100_bases
ATGGTTCTTCCCCTTGCTATTACAAATTGTAAATAATTAAAATATAAATATCATCATGGATTTATTTGACAAAGTCAGCG
AAGACATTAAAAACGCAATG

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MDEIVQFDFPTDSPKIIKVIGVGGGGGNAVNHMYREGIHDVTFVLCNTDNQALAESPVPVKLQLGRSITQGLGAGNRPER
ARDAAEESIDDIKEQLNDGTKMVFITAGMGGGTGTGAAPVIARIAKEMDILTVGIVTIPFIFEGEKKIIQALDGVERIAQ
HVDALLVINNERLREIYADLTFMNAFGKADDTLSIAAKSIAEIITMRGTVNLDFADVKTILKDGGVAIMSTGFGEGENRV
TKAIDDALHSPLLNNNDIFNAKKVMLNVSFCPTSELMMEEMNEIHEFMSKFREGVEVIWGVAVDNSLDTKVKITVLATGF
GVEDVPGMDTLHEARSQEEEERQLQLEEEKEKNKERIRKAYGESAGIGKKSLRSRRHIYIFNTEDLDNDDIIAMIEESPT
YTRDKTKLLKIKTKAALEEEVAMEEATDNDGVITF

Sequences:

>Translated_435_residues
MDEIVQFDFPTDSPKIIKVIGVGGGGGNAVNHMYREGIHDVTFVLCNTDNQALAESPVPVKLQLGRSITQGLGAGNRPER
ARDAAEESIDDIKEQLNDGTKMVFITAGMGGGTGTGAAPVIARIAKEMDILTVGIVTIPFIFEGEKKIIQALDGVERIAQ
HVDALLVINNERLREIYADLTFMNAFGKADDTLSIAAKSIAEIITMRGTVNLDFADVKTILKDGGVAIMSTGFGEGENRV
TKAIDDALHSPLLNNNDIFNAKKVMLNVSFCPTSELMMEEMNEIHEFMSKFREGVEVIWGVAVDNSLDTKVKITVLATGF
GVEDVPGMDTLHEARSQEEEERQLQLEEEKEKNKERIRKAYGESAGIGKKSLRSRRHIYIFNTEDLDNDDIIAMIEESPT
YTRDKTKLLKIKTKAALEEEVAMEEATDNDGVITF
>Mature_435_residues
MDEIVQFDFPTDSPKIIKVIGVGGGGGNAVNHMYREGIHDVTFVLCNTDNQALAESPVPVKLQLGRSITQGLGAGNRPER
ARDAAEESIDDIKEQLNDGTKMVFITAGMGGGTGTGAAPVIARIAKEMDILTVGIVTIPFIFEGEKKIIQALDGVERIAQ
HVDALLVINNERLREIYADLTFMNAFGKADDTLSIAAKSIAEIITMRGTVNLDFADVKTILKDGGVAIMSTGFGEGENRV
TKAIDDALHSPLLNNNDIFNAKKVMLNVSFCPTSELMMEEMNEIHEFMSKFREGVEVIWGVAVDNSLDTKVKITVLATGF
GVEDVPGMDTLHEARSQEEEERQLQLEEEKEKNKERIRKAYGESAGIGKKSLRSRRHIYIFNTEDLDNDDIIAMIEESPT
YTRDKTKLLKIKTKAALEEEVAMEEATDNDGVITF

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=301, Percent_Identity=42.1926910299003, Blast_Score=207, Evalue=1e-54,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 47800; Mature: 47800

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEIVQFDFPTDSPKIIKVIGVGGGGGNAVNHMYREGIHDVTFVLCNTDNQALAESPVPV
CCCCEEECCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHCCCCCE
KLQLGRSITQGLGAGNRPERARDAAEESIDDIKEQLNDGTKMVFITAGMGGGTGTGAAPV
EEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHH
IARIAKEMDILTVGIVTIPFIFEGEKKIIQALDGVERIAQHVDALLVINNERLREIYADL
HHHHHHHHHHEEEHHHHCCEEECCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHH
TFMNAFGKADDTLSIAAKSIAEIITMRGTVNLDFADVKTILKDGGVAIMSTGFGEGENRV
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHCCCEEEEECCCCCCHHHH
TKAIDDALHSPLLNNNDIFNAKKVMLNVSFCPTSELMMEEMNEIHEFMSKFREGVEVIWG
HHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHEEEE
VAVDNSLDTKVKITVLATGFGVEDVPGMDTLHEARSQEEEERQLQLEEEKEKNKERIRKA
EEECCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHH
YGESAGIGKKSLRSRRHIYIFNTEDLDNDDIIAMIEESPTYTRDKTKLLKIKTKAALEEE
HCCCCCCCHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHH
VAMEEATDNDGVITF
HHHHHCCCCCCEEEC
>Mature Secondary Structure
MDEIVQFDFPTDSPKIIKVIGVGGGGGNAVNHMYREGIHDVTFVLCNTDNQALAESPVPV
CCCCEEECCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHCCCCCE
KLQLGRSITQGLGAGNRPERARDAAEESIDDIKEQLNDGTKMVFITAGMGGGTGTGAAPV
EEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHH
IARIAKEMDILTVGIVTIPFIFEGEKKIIQALDGVERIAQHVDALLVINNERLREIYADL
HHHHHHHHHHEEEHHHHCCEEECCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHH
TFMNAFGKADDTLSIAAKSIAEIITMRGTVNLDFADVKTILKDGGVAIMSTGFGEGENRV
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHCCCEEEEECCCCCCHHHH
TKAIDDALHSPLLNNNDIFNAKKVMLNVSFCPTSELMMEEMNEIHEFMSKFREGVEVIWG
HHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHEEEE
VAVDNSLDTKVKITVLATGFGVEDVPGMDTLHEARSQEEEERQLQLEEEKEKNKERIRKA
EEECCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHH
YGESAGIGKKSLRSRRHIYIFNTEDLDNDDIIAMIEESPTYTRDKTKLLKIKTKAALEEE
HCCCCCCCHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHH
VAMEEATDNDGVITF
HHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]