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The map label for this gene is aslA [H]

Identifier: 29348518

GI number: 29348518

Start: 3955003

End: 3956529

Strand: Reverse

Name: aslA [H]

Synonym: BT_3109

Alternate gene names: 29348518

Gene position: 3956529-3955003 (Counterclockwise)

Preceding gene: 29348530

Following gene: 29348517

Centisome position: 63.2

GC content: 43.03

Gene sequence:

>1527_bases
ATGAAAAAAATAATCTATCTTGTTCCTGCGTTATCTTTAGCAGGTTGCACTTCACAGCAGGTAGAAGAAAAGCCGAATGT
GATTGTCATTCTTGCTGATGATCTGGGGTTCGGTGATGTCAGTGCTTATGGTTCAACTACTATTCATACACCGAATATTG
ACAGTCTTGCCCGTGGGGGAGTTTGTTTCACAAATGGATATGCTACTTCGGCTACTTCTACCCCCAGTCGTTATGCCCTA
ATGACCGGAATGTATCCATGGAAGAATAAAGATGCAAAAATCCTTCCGGGTGATGCTCCTCTTATTATCAACGAGAGCCA
ATACACTTTACCAAAGATGATGCGAGAGTGTGGTTATGTGACCGGAGCTATCGGAAAATGGCATTTGGGCATGGGAAATG
GAAATGTCAATTGGAATGAGACAGTCAAGCCGGGAGCAAAAGAGATTGGCTTTGATTACTCTTGTCTGATTGCGGCAACA
AATGACCGCGTTCCGACTGTTTATGTAGAAAATGGAGATGTGGTAGGTCGTGATCCGTCAGATCCTATTGAGGTGAGTTA
TGAACAGAACTTTGAGGGGGAGCCGACTGCTATATCCAATCCCGAAATGCTGAAAATGCAATGGGCGCACGGACATAATA
ATTCGATTGTAAATGGAATACCCCGTATCGGTTATATGAAAGGTGGGAAGAAAGCCCGTTGGAAAGACGAAGATATGGCT
GATTATTTTGTAGACAAGGTAAAGAACTTTATTACTGAACACAGAGACTCTTCATTCTTTCTTTATTATGGTTTGCATGA
ACCTCATGTGCCACGCGCGCCTCATCAACGTTTTGTTGGGAAAACGACTATGGGACCTCGTGGAGATGCAATTGTGGAAG
CAGACTGGTGTGTGGGTGAATTACTAACTTATTTGAAGAAAGAAGGACTTCTGGAAAAGACTCTGATTATTTTTTCAAGT
GACAATGGTCCGGTTTTGAATGATGGATATAAAGATGGTGCTCCCGAACTGGCTGGCAAGCACGCTCCTGCCGGAGGATT
ACGTGGTGGTAAATATAGTTTGTTCGATGGAGGTACACATATTCCTTTATTCGTTTATTGGAAAGGAAAGATTCAGCCTG
TAAAATCGGATGCACTAGTCTGCCAGATGGACTTGTTGGCGTCTTTAGGAAGCATGGTGGGAGCCACTCTGCCGGATGGA
CTGGATAGTCGCAACTATTTAAATGCATTCATGGGAACAGAACTGAAAGCTCGTGAAAATTTGATTATTGAAGCTCAAGG
CAGACTGGGTTACCGCAGTGGTGACTGGATTATGATGCCACCTTATAAAGGTTCGCAAAGAAACCTGACCGGAAATGAAT
TGGGGAACTTGGATGAATTCAGTCTGTTTGATGTAAAATCAGACAAGGGACAGAAATCTAATGTAGCTGGCAGACATCCG
GAACTGCTTGAGCGGTTAAAGCAGGAATTTTTTGTGCAAACAGATGGATTTTATCGTAGTGAGGTGGAAGAAGAACCATT
AAAATAA

Upstream 100 bases:

>100_bases
TATAGATATGGATGGACATTACTCCCTATTATTAAACATATGTTCTATTTAAATAAATAAGCACTGACTAAATTTGCATC
ATTATAAACTATATAATATT

Downstream 100 bases:

>100_bases
GCCCGATAACCCCTTCTGGAAAGCATTTGATTGATTAGGTATTAGATTGTTTTGCAGGAATTGGTGTAGAAGGATAGTTT
CTGAACATGTGTGCTCATAA

Product: arylsulfatase A

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MKKIIYLVPALSLAGCTSQQVEEKPNVIVILADDLGFGDVSAYGSTTIHTPNIDSLARGGVCFTNGYATSATSTPSRYAL
MTGMYPWKNKDAKILPGDAPLIINESQYTLPKMMRECGYVTGAIGKWHLGMGNGNVNWNETVKPGAKEIGFDYSCLIAAT
NDRVPTVYVENGDVVGRDPSDPIEVSYEQNFEGEPTAISNPEMLKMQWAHGHNNSIVNGIPRIGYMKGGKKARWKDEDMA
DYFVDKVKNFITEHRDSSFFLYYGLHEPHVPRAPHQRFVGKTTMGPRGDAIVEADWCVGELLTYLKKEGLLEKTLIIFSS
DNGPVLNDGYKDGAPELAGKHAPAGGLRGGKYSLFDGGTHIPLFVYWKGKIQPVKSDALVCQMDLLASLGSMVGATLPDG
LDSRNYLNAFMGTELKARENLIIEAQGRLGYRSGDWIMMPPYKGSQRNLTGNELGNLDEFSLFDVKSDKGQKSNVAGRHP
ELLERLKQEFFVQTDGFYRSEVEEEPLK

Sequences:

>Translated_508_residues
MKKIIYLVPALSLAGCTSQQVEEKPNVIVILADDLGFGDVSAYGSTTIHTPNIDSLARGGVCFTNGYATSATSTPSRYAL
MTGMYPWKNKDAKILPGDAPLIINESQYTLPKMMRECGYVTGAIGKWHLGMGNGNVNWNETVKPGAKEIGFDYSCLIAAT
NDRVPTVYVENGDVVGRDPSDPIEVSYEQNFEGEPTAISNPEMLKMQWAHGHNNSIVNGIPRIGYMKGGKKARWKDEDMA
DYFVDKVKNFITEHRDSSFFLYYGLHEPHVPRAPHQRFVGKTTMGPRGDAIVEADWCVGELLTYLKKEGLLEKTLIIFSS
DNGPVLNDGYKDGAPELAGKHAPAGGLRGGKYSLFDGGTHIPLFVYWKGKIQPVKSDALVCQMDLLASLGSMVGATLPDG
LDSRNYLNAFMGTELKARENLIIEAQGRLGYRSGDWIMMPPYKGSQRNLTGNELGNLDEFSLFDVKSDKGQKSNVAGRHP
ELLERLKQEFFVQTDGFYRSEVEEEPLK
>Mature_508_residues
MKKIIYLVPALSLAGCTSQQVEEKPNVIVILADDLGFGDVSAYGSTTIHTPNIDSLARGGVCFTNGYATSATSTPSRYAL
MTGMYPWKNKDAKILPGDAPLIINESQYTLPKMMRECGYVTGAIGKWHLGMGNGNVNWNETVKPGAKEIGFDYSCLIAAT
NDRVPTVYVENGDVVGRDPSDPIEVSYEQNFEGEPTAISNPEMLKMQWAHGHNNSIVNGIPRIGYMKGGKKARWKDEDMA
DYFVDKVKNFITEHRDSSFFLYYGLHEPHVPRAPHQRFVGKTTMGPRGDAIVEADWCVGELLTYLKKEGLLEKTLIIFSS
DNGPVLNDGYKDGAPELAGKHAPAGGLRGGKYSLFDGGTHIPLFVYWKGKIQPVKSDALVCQMDLLASLGSMVGATLPDG
LDSRNYLNAFMGTELKARENLIIEAQGRLGYRSGDWIMMPPYKGSQRNLTGNELGNLDEFSLFDVKSDKGQKSNVAGRHP
ELLERLKQEFFVQTDGFYRSEVEEEPLK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI146229331, Length=486, Percent_Identity=29.4238683127572, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI146229329, Length=486, Percent_Identity=29.4238683127572, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI6005990, Length=486, Percent_Identity=29.4238683127572, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI146229324, Length=486, Percent_Identity=29.4238683127572, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI4503899, Length=425, Percent_Identity=27.0588235294118, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI31742482, Length=469, Percent_Identity=27.7185501066098, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI71852584, Length=445, Percent_Identity=25.6179775280899, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI146229327, Length=395, Percent_Identity=27.0886075949367, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI45430057, Length=513, Percent_Identity=25.9259259259259, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI71852586, Length=314, Percent_Identity=27.0700636942675, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI53831991, Length=118, Percent_Identity=44.9152542372881, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI58743319, Length=123, Percent_Identity=41.4634146341463, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI157266309, Length=134, Percent_Identity=40.2985074626866, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI38569407, Length=108, Percent_Identity=42.5925925925926, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI38569405, Length=108, Percent_Identity=42.5925925925926, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI109389362, Length=115, Percent_Identity=40, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI59797060, Length=107, Percent_Identity=41.1214953271028, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790233, Length=483, Percent_Identity=27.9503105590062, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081924, Length=432, Percent_Identity=29.1666666666667, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790112, Length=408, Percent_Identity=22.5490196078431, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559078, Length=129, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115533416, Length=125, Percent_Identity=37.6, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281366397, Length=441, Percent_Identity=27.2108843537415, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281366395, Length=441, Percent_Identity=27.2108843537415, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24666163, Length=441, Percent_Identity=27.2108843537415, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281363223, Length=468, Percent_Identity=26.0683760683761, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24666175, Length=451, Percent_Identity=26.1640798226164, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666109, Length=112, Percent_Identity=40.1785714285714, Blast_Score=88, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 56063; Mature: 56063

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIYLVPALSLAGCTSQQVEEKPNVIVILADDLGFGDVSAYGSTTIHTPNIDSLARGG
CCEEEEEECCHHHCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEECCCHHHHHCCC
VCFTNGYATSATSTPSRYALMTGMYPWKNKDAKILPGDAPLIINESQYTLPKMMRECGYV
EEEECCEECCCCCCCCCEEEEECCCCCCCCCCEEECCCCCEEECCCCCHHHHHHHHCCCE
TGAIGKWHLGMGNGNVNWNETVKPGAKEIGFDYSCLIAATNDRVPTVYVENGDVVGRDPS
ECCCCEEEEECCCCCCCCCCCCCCCHHHHCCCEEEEEEECCCCCCEEEEECCEEECCCCC
DPIEVSYEQNFEGEPTAISNPEMLKMQWAHGHNNSIVNGIPRIGYMKGGKKARWKDEDMA
CCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCHHCCCCCCCEECCCCCCCCCCCHHH
DYFVDKVKNFITEHRDSSFFLYYGLHEPHVPRAPHQRFVGKTTMGPRGDAIVEADWCVGE
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCEEEECCHHHHH
LLTYLKKEGLLEKTLIIFSSDNGPVLNDGYKDGAPELAGKHAPAGGLRGGKYSLFDGGTH
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEECCCCC
IPLFVYWKGKIQPVKSDALVCQMDLLASLGSMVGATLPDGLDSRNYLNAFMGTELKAREN
CEEEEEECCEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEECCCC
LIIEAQGRLGYRSGDWIMMPPYKGSQRNLTGNELGNLDEFSLFDVKSDKGQKSNVAGRHP
EEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCH
ELLERLKQEFFVQTDGFYRSEVEEEPLK
HHHHHHHHHHEECCCCCCHHCCCCCCCC
>Mature Secondary Structure
MKKIIYLVPALSLAGCTSQQVEEKPNVIVILADDLGFGDVSAYGSTTIHTPNIDSLARGG
CCEEEEEECCHHHCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEECCCHHHHHCCC
VCFTNGYATSATSTPSRYALMTGMYPWKNKDAKILPGDAPLIINESQYTLPKMMRECGYV
EEEECCEECCCCCCCCCEEEEECCCCCCCCCCEEECCCCCEEECCCCCHHHHHHHHCCCE
TGAIGKWHLGMGNGNVNWNETVKPGAKEIGFDYSCLIAATNDRVPTVYVENGDVVGRDPS
ECCCCEEEEECCCCCCCCCCCCCCCHHHHCCCEEEEEEECCCCCCEEEEECCEEECCCCC
DPIEVSYEQNFEGEPTAISNPEMLKMQWAHGHNNSIVNGIPRIGYMKGGKKARWKDEDMA
CCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCHHCCCCCCCEECCCCCCCCCCCHHH
DYFVDKVKNFITEHRDSSFFLYYGLHEPHVPRAPHQRFVGKTTMGPRGDAIVEADWCVGE
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCEEEECCHHHHH
LLTYLKKEGLLEKTLIIFSSDNGPVLNDGYKDGAPELAGKHAPAGGLRGGKYSLFDGGTH
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEECCCCC
IPLFVYWKGKIQPVKSDALVCQMDLLASLGSMVGATLPDGLDSRNYLNAFMGTELKAREN
CEEEEEECCEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEECCCC
LIIEAQGRLGYRSGDWIMMPPYKGSQRNLTGNELGNLDEFSLFDVKSDKGQKSNVAGRHP
EEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCH
ELLERLKQEFFVQTDGFYRSEVEEEPLK
HHHHHHHHHHEECCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]