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The map label for this gene is wzb [C]

Identifier: 29348159

GI number: 29348159

Start: 3408455

End: 3408925

Strand: Reverse

Name: wzb [C]

Synonym: BT_2750

Alternate gene names: 29348159

Gene position: 3408925-3408455 (Counterclockwise)

Preceding gene: 29348160

Following gene: 29348157

Centisome position: 54.45

GC content: 48.2

Gene sequence:

>471_bases
ATGAAGAAAATATTATTTGTCTGCCTCGGAAATATCTGCCGTAGCTCTACGGCGGAAGGAGTAATGCTTCACCTGATCAA
AGAAGCCGGACTGGAAAAAGAATTTGTGATTGATTCCGCCGGAATCCTGTCTTATCATCAAGGCGAATTGCCGGATAGCC
GGATGCGTGCACACGCTGCCCGTCGGGGCTATCAACTGGTTCATCGCTCCCGTCCGGTGCGGACAGAGGACTTTTATAAT
TTTGATTTGATTATTGGCATGGACGACCGTAACATAGATGATCTGAAAGAAAAAGCTCCTTCTACGGAAGAGTGGAAAAA
GATTCATCGTATGACGGAGTACTGTACCCGCATTCCCGCCGACCATGTCCCCGACCCCTACTATGGAGGGGCCGAAGGAT
TTGAATATGTGCTGGATGTACTCGAAGACGCTTGCGCTGGTCTGCTTACTTCTTTAACTCAGGATAACTGA

Upstream 100 bases:

>100_bases
GGAAATACCAGCAGCCGTTACCGTAAACCGGGCCAATCAGATACTTCATTCGTTTTGATAATAGAAACGAATGAAGCCTG
TCAATTATTAAACGTAAATT

Downstream 100 bases:

>100_bases
TCCGTGTGTGATAAGCGATCTTCAGTTTTTCTTTGAATACCGTCTTGATGGTCGCAATGTCCTTGAAAGTGATAGGGCAT
TCTTTGAAATAACCTTCAGC

Product: putative protein-tyrosine-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKKILFVCLGNICRSSTAEGVMLHLIKEAGLEKEFVIDSAGILSYHQGELPDSRMRAHAARRGYQLVHRSRPVRTEDFYN
FDLIIGMDDRNIDDLKEKAPSTEEWKKIHRMTEYCTRIPADHVPDPYYGGAEGFEYVLDVLEDACAGLLTSLTQDN

Sequences:

>Translated_156_residues
MKKILFVCLGNICRSSTAEGVMLHLIKEAGLEKEFVIDSAGILSYHQGELPDSRMRAHAARRGYQLVHRSRPVRTEDFYN
FDLIIGMDDRNIDDLKEKAPSTEEWKKIHRMTEYCTRIPADHVPDPYYGGAEGFEYVLDVLEDACAGLLTSLTQDN
>Mature_156_residues
MKKILFVCLGNICRSSTAEGVMLHLIKEAGLEKEFVIDSAGILSYHQGELPDSRMRAHAARRGYQLVHRSRPVRTEDFYN
FDLIIGMDDRNIDDLKEKAPSTEEWKKIHRMTEYCTRIPADHVPDPYYGGAEGFEYVLDVLEDACAGLLTSLTQDN

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=151, Percent_Identity=35.7615894039735, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI4757714, Length=151, Percent_Identity=36.4238410596026, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325330, Length=136, Percent_Identity=36.7647058823529, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI78706766, Length=155, Percent_Identity=34.8387096774194, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706768, Length=155, Percent_Identity=34.8387096774194, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78711846, Length=157, Percent_Identity=32.484076433121, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI78706770, Length=147, Percent_Identity=35.3741496598639, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78706772, Length=147, Percent_Identity=35.3741496598639, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78706764, Length=128, Percent_Identity=34.375, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17751; Mature: 17751

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILFVCLGNICRSSTAEGVMLHLIKEAGLEKEFVIDSAGILSYHQGELPDSRMRAHAA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCHHCCCCCCCCHHHHHHHHH
RRGYQLVHRSRPVRTEDFYNFDLIIGMDDRNIDDLKEKAPSTEEWKKIHRMTEYCTRIPA
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
DHVPDPYYGGAEGFEYVLDVLEDACAGLLTSLTQDN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKILFVCLGNICRSSTAEGVMLHLIKEAGLEKEFVIDSAGILSYHQGELPDSRMRAHAA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCCHHCCCCCCCCHHHHHHHHH
RRGYQLVHRSRPVRTEDFYNFDLIIGMDDRNIDDLKEKAPSTEEWKKIHRMTEYCTRIPA
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
DHVPDPYYGGAEGFEYVLDVLEDACAGLLTSLTQDN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]