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The map label for this gene is rpoC [H]

Identifier: 29348142

GI number: 29348142

Start: 3382547

End: 3386830

Strand: Reverse

Name: rpoC [H]

Synonym: BT_2733

Alternate gene names: 29348142

Gene position: 3386830-3382547 (Counterclockwise)

Preceding gene: 29348143

Following gene: 29348141

Centisome position: 54.1

GC content: 43.51

Gene sequence:

>4284_bases
ATGGCTTTTAGAAAAGAAAATAAGACGAAAAGCAATTTCTCGAAGATCTCAATTGGTCTGGCTTCTCCGGAAGAAATCCT
AGAGAATTCGAGTGGTGAAGTTTTGAAGCCTGAAACCATAAATTACCGTACGTACAAACCCGAACGCGATGGTTTGTTCT
GCGAGCGCATTTTTGGTCCTATTAAGGATTACGAATGCCATTGCGGTAAATATAAGCGTATCCGTTATAAAGGTATCGTC
TGCGACCGTTGTGGTGTAGAAGTTACAGAAAAGAAAGTACGCCGTGAACGTATGGGACATATACAGTTGGTGGTGCCGGT
GGCACACATCTGGTATTTCCGTTCGCTTCCAAATAAGATCGGTTATTTGCTCGGACTGCCGACAAAGAAGCTGGATTCGA
TTATATATTACGAACGTTATGTTGTTATTCAGCCGGGTGTAAAGGCTGAAGATGGCATTGCCGAATATGATTTACTTTCT
GAAGAAGAATATCTGGATATTCTGGATACACTTCCGAAGGACAATCAATATCTGGAGGATAATGATCCGAATAAGTTCAT
CGCTAAGATGGGAGCTGAAGCAATCTATGATTTGCTGGCTCGTTTGGATCTGGATGCTCTGTCTTATGAATTGCGTCACC
GTGCAGGCAATGATGCTTCACAGCAACGTAAGAATGAGGCATTGAAACGTCTGCAGGTTGTAGAATCGTTCCGTGCATCA
CGTGGACGTAACAAGCCGGAATGGATGATTGTACGTATCGTACCGGTTATTCCGCCCGAACTCCGTCCATTGGTTCCATT
GGATGGTGGTCGTTTTGCTACTTCTGACTTGAATGACCTTTATCGTCGTGTTATCATTCGTAACAACCGTCTGAAGAGAT
TGATCGAAATCAAAGCTCCGGAAGTAATCTTGCGTAATGAGAAACGTATGCTTCAGGAATCTGTAGACTCATTGTTCGAT
AATTCACGTAAATCAAGTGCAGTGAAGACGGATGCTAACCGTCCGTTGAAATCACTGTCTGATAGCTTGAAAGGTAAACA
AGGACGTTTCCGTCAGAACTTGTTGGGTAAACGTGTTGACTACTCTGCACGTTCGGTAATTGTCGTTGGTCCGGAACTGA
AGATGGGTGAGTGCGGTATTCCTAAATTGATGGCTGCCGAACTTTATAAGCCGTTTATTATCCGTAAGCTCATTGAACGT
GGTATCGTTAAGACGGTGAAATCTGCAAAGAAGATTGTAGATCGTAAGGAAGCGGTGATCTGGGATATTCTGGAACACGT
AATGAAAGGACATCCTGTACTGTTGAACCGTGCTCCGACATTGCACCGTTTGGGTATCCAGGCATTCCAGCCGAAGATGA
TCGAAGGTAAAGCTATCCAGTTGCACCCGTTGGCATGTACGGCATTCAACGCCGACTTCGACGGTGACCAGATGGCTGTT
CACTTGCCTTTGAGTAACGAAGCAATTCTTGAAGCTCAGATGTTGATGCTTCAGTCACATAATATCCTGAATCCGGCAAA
TGGTGCGCCTATTACTGTGCCTGCACAGGATATGGTTCTTGGTTTGTATTACATTACCAAGTTGCGTGCTGGTGCTAAGG
GAGAAGGACTTACATTCTACGGACCGGAAGAAGCATTAATCGCTTATAATGAAGGTAAGGTAGATATTCATGCTCCGGTA
AAGGTGATCGTGAAAGACGTTGATGAAAATGGTAACATTGTTGACGTTATGCGTGAAACTTCTGTAGGACGTGTGATTGT
TAATGAAATTGTTCCTCCTGAAGCAGGTTATATCAATACGATTATTTCTAAGAAATCTCTTCGTGATATCATTAGTGATG
TAATCAAGGTTTGTGGTGTGGCTAAAGCTGCAGACTTCTTGGATGGAATCAAGAACTTAGGTTACCAAATGGCCTTTAAG
GGTGGTTTGTCATTCAACTTGGGTGATATTATTATCCCGAAAGAAAAAGAGACATTGGTACAAAAAGGTTACGACGAAGT
TGAACAAGTCGTAAACAACTATAATATGGGTTTCATTACCAACAACGAACGTTATAATCAGGTAATTGATATCTGGACAC
ATGTGAACTCTGAGTTGTCTAACATCTTGATGAAAACTATTTCTTCGGATGACCAAGGATTTAACTCTGTATACATGATG
CTGGATTCGGGTGCCCGTGGTTCTAAAGAACAGATTCGTCAGTTGTCCGGTATGCGTGGTTTGATGGCTAAGCTCCAGAA
AGCTGGTGCTGAAGGTGGTCAGATTATTGAAAACCCGATCTTGTCAAACTTTAAAGAGGGACTTTCTGTGTTGGAGTACT
TTATCTCTACTCACGGTGCCCGTAAAGGTTTGGCGGATACCGCTTTGAAGACTGCCGATGCCGGATATTTGACTCGTCGT
CTGGTAGACGTTTCTCACGACGTGATCATCACGGAAGAAGACTGCGGTACACTTCGTGGATTGGTTTGTACAGACTTGAA
GAATAACGATGAAGTAATCGCTACCCTGTATGAACGCATCTTAGGTCGTGTTTCTGTACATGATATTATTCATCCTACTA
CAGGCGAATTGCTTGTTGCCGGTGGTGAAGAAATCACAGAAGAAGTTGCTAAGAAGATTCAGGATTCTCCGATTGAAAGC
GTTGAAATCCGTTCTGTATTGACTTGTGAAGCGAAGAAGGGTGTTTGTGCTAAGTGTTACGGACGTAACCTGGCAACAAG
CCGCATGGTTCAGAAGGGTGAGGCTGTCGGTGTAATTGCTGCTCAGTCAATCGGTGAGCCGGGTACACAGTTGACATTGC
GTACATTCCACGCTGGTGGTACTGCTGCGAATATTGCGGCAAATGCAAGTATTGTGGCTAAGAACAGTGCTCGTCTGGAA
TTTGAAGAACTTCGTACGGTAGATATCGTAGACGAAATGGGTGAAGCTGCAAAAGTAGTGGTAGGCCGTTTGGCTGAAGT
TCGTTTTGTGGACGTAAATACTGGTATCGTTCTTTCTACGCACAATGTACCTTATGGTTCTACATTATATGTATCGGATG
GTGATCTGGTTGAAAAGGGTAAGTTAATTGCTAAATGGGACCCGTTCAATGCCGTTATTATAACTGAAGCAACTGGTAAG
ATTGAATTCGAAGGTGTAATTGAGAATGTTACCTATAAAGTGGAATCGGATGAAGCAACCGGTCTTCGTGAAATCATCAT
TATTGAATCTAAGGATAAAACGAAAGTTCCTTCGGCTCATATCCTGACAGAAGACGGTGATCTGATTCGTACTTATAACT
TACCGGTAGGTGGTCACGTGATTATTGAAAATGGTCAGAAAGTGAAAGCCGGTGAAGTAATCGTGAAGATTCCGCGTGCT
GTAGGTAAGGCGGGTGACATCACGGGTGGTCTTCCTCGTGTTACTGAGTTGTTTGAAGCACGTAATCCGTCTAATCCTGC
TGTCGTTTCTGAAATTGACGGTGAGGTTACAATGGGTAAGATCAAGCGTGGTAACCGTGAAATCATCGTAACTTCGAAAA
CAGGTGAAGTGAAGAAGTATCTTGTTGCATTGTCCAAACAGATTCTGGTTCAGGAGAACGACTATGTGCGTGCTGGTACT
CCATTATCTGACGGTGCTACTACTCCGGCTGATATCCTGGCAATTAAAGGTCCTACGGCTGTACAGGAATATATTGTGAA
TGAAGTTCAGGATGTATACCGTCTGCAGGGTGTGAAGATCAATGATAAGCATTTTGAGATTATCGTTCGCCAGATGATGC
GTAAGGTTCAGATCGATGAGCCGGGTGATACTCGCTTCTTGGAACAACAGGTAGTGGATAAGCTTGAGTTTATGGAGGAA
AACGATCGTATCTGGGGTAAGAAAGTGGTTGTTGATGCAGGTGATTCTCAGAATATGCAGCCGGGACAGATTGTGACTGC
CCGTAAGTTGCGTGATGAGAACAGTATGCTGAAGCGCCGTGACTTGAAACCTGTTGAGGTACGTGATGCTGTAGCTGCAA
CTTCTACTCAGATTCTTCAGGGTATTACGCGTGCTGCACTGCAGACTTCAAGCTTTATGTCAGCTGCATCCTTCCAGGAA
ACAACGAAGGTGTTGAATGAGGCTGCTATCAATGGCAAGACAGATAAACTTGAAGGAATGAAGGAAAACGTAATTTGCGG
TCACTTAATTCCGGCAGGTACAGGTCAGCGTGAATTTGAAAAGATTATCGTTGGTTCAAAAGAAGAGTATGATCGTATCT
TGGCGAACAAGAAGACAGTACTTGATTACAATGAAGTAGAATAA

Upstream 100 bases:

>100_bases
GAAAGAATGCAGGATGTCAATAGGCCGATGAAGGTCTGTTGACATTCGCATCTTCTTCAATTTCCAATGATTCAATTATC
AAATCTCAATTATATAGAGT

Downstream 100 bases:

>100_bases
TACAATTCAATTGACTATATGAAAAAGGAGCGATTGCTGTAGCAGGCAGTTGCTCCTTTTTTTGTTTCTTTTACCTGACT
GTATCATTCTTATCTCGATA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1427; Mature: 1426

Protein sequence:

>1427_residues
MAFRKENKTKSNFSKISIGLASPEEILENSSGEVLKPETINYRTYKPERDGLFCERIFGPIKDYECHCGKYKRIRYKGIV
CDRCGVEVTEKKVRRERMGHIQLVVPVAHIWYFRSLPNKIGYLLGLPTKKLDSIIYYERYVVIQPGVKAEDGIAEYDLLS
EEEYLDILDTLPKDNQYLEDNDPNKFIAKMGAEAIYDLLARLDLDALSYELRHRAGNDASQQRKNEALKRLQVVESFRAS
RGRNKPEWMIVRIVPVIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLIEIKAPEVILRNEKRMLQESVDSLFD
NSRKSSAVKTDANRPLKSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELKMGECGIPKLMAAELYKPFIIRKLIER
GIVKTVKSAKKIVDRKEAVIWDILEHVMKGHPVLLNRAPTLHRLGIQAFQPKMIEGKAIQLHPLACTAFNADFDGDQMAV
HLPLSNEAILEAQMLMLQSHNILNPANGAPITVPAQDMVLGLYYITKLRAGAKGEGLTFYGPEEALIAYNEGKVDIHAPV
KVIVKDVDENGNIVDVMRETSVGRVIVNEIVPPEAGYINTIISKKSLRDIISDVIKVCGVAKAADFLDGIKNLGYQMAFK
GGLSFNLGDIIIPKEKETLVQKGYDEVEQVVNNYNMGFITNNERYNQVIDIWTHVNSELSNILMKTISSDDQGFNSVYMM
LDSGARGSKEQIRQLSGMRGLMAKLQKAGAEGGQIIENPILSNFKEGLSVLEYFISTHGARKGLADTALKTADAGYLTRR
LVDVSHDVIITEEDCGTLRGLVCTDLKNNDEVIATLYERILGRVSVHDIIHPTTGELLVAGGEEITEEVAKKIQDSPIES
VEIRSVLTCEAKKGVCAKCYGRNLATSRMVQKGEAVGVIAAQSIGEPGTQLTLRTFHAGGTAANIAANASIVAKNSARLE
FEELRTVDIVDEMGEAAKVVVGRLAEVRFVDVNTGIVLSTHNVPYGSTLYVSDGDLVEKGKLIAKWDPFNAVIITEATGK
IEFEGVIENVTYKVESDEATGLREIIIIESKDKTKVPSAHILTEDGDLIRTYNLPVGGHVIIENGQKVKAGEVIVKIPRA
VGKAGDITGGLPRVTELFEARNPSNPAVVSEIDGEVTMGKIKRGNREIIVTSKTGEVKKYLVALSKQILVQENDYVRAGT
PLSDGATTPADILAIKGPTAVQEYIVNEVQDVYRLQGVKINDKHFEIIVRQMMRKVQIDEPGDTRFLEQQVVDKLEFMEE
NDRIWGKKVVVDAGDSQNMQPGQIVTARKLRDENSMLKRRDLKPVEVRDAVAATSTQILQGITRAALQTSSFMSAASFQE
TTKVLNEAAINGKTDKLEGMKENVICGHLIPAGTGQREFEKIIVGSKEEYDRILANKKTVLDYNEVE

Sequences:

>Translated_1427_residues
MAFRKENKTKSNFSKISIGLASPEEILENSSGEVLKPETINYRTYKPERDGLFCERIFGPIKDYECHCGKYKRIRYKGIV
CDRCGVEVTEKKVRRERMGHIQLVVPVAHIWYFRSLPNKIGYLLGLPTKKLDSIIYYERYVVIQPGVKAEDGIAEYDLLS
EEEYLDILDTLPKDNQYLEDNDPNKFIAKMGAEAIYDLLARLDLDALSYELRHRAGNDASQQRKNEALKRLQVVESFRAS
RGRNKPEWMIVRIVPVIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLIEIKAPEVILRNEKRMLQESVDSLFD
NSRKSSAVKTDANRPLKSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELKMGECGIPKLMAAELYKPFIIRKLIER
GIVKTVKSAKKIVDRKEAVIWDILEHVMKGHPVLLNRAPTLHRLGIQAFQPKMIEGKAIQLHPLACTAFNADFDGDQMAV
HLPLSNEAILEAQMLMLQSHNILNPANGAPITVPAQDMVLGLYYITKLRAGAKGEGLTFYGPEEALIAYNEGKVDIHAPV
KVIVKDVDENGNIVDVMRETSVGRVIVNEIVPPEAGYINTIISKKSLRDIISDVIKVCGVAKAADFLDGIKNLGYQMAFK
GGLSFNLGDIIIPKEKETLVQKGYDEVEQVVNNYNMGFITNNERYNQVIDIWTHVNSELSNILMKTISSDDQGFNSVYMM
LDSGARGSKEQIRQLSGMRGLMAKLQKAGAEGGQIIENPILSNFKEGLSVLEYFISTHGARKGLADTALKTADAGYLTRR
LVDVSHDVIITEEDCGTLRGLVCTDLKNNDEVIATLYERILGRVSVHDIIHPTTGELLVAGGEEITEEVAKKIQDSPIES
VEIRSVLTCEAKKGVCAKCYGRNLATSRMVQKGEAVGVIAAQSIGEPGTQLTLRTFHAGGTAANIAANASIVAKNSARLE
FEELRTVDIVDEMGEAAKVVVGRLAEVRFVDVNTGIVLSTHNVPYGSTLYVSDGDLVEKGKLIAKWDPFNAVIITEATGK
IEFEGVIENVTYKVESDEATGLREIIIIESKDKTKVPSAHILTEDGDLIRTYNLPVGGHVIIENGQKVKAGEVIVKIPRA
VGKAGDITGGLPRVTELFEARNPSNPAVVSEIDGEVTMGKIKRGNREIIVTSKTGEVKKYLVALSKQILVQENDYVRAGT
PLSDGATTPADILAIKGPTAVQEYIVNEVQDVYRLQGVKINDKHFEIIVRQMMRKVQIDEPGDTRFLEQQVVDKLEFMEE
NDRIWGKKVVVDAGDSQNMQPGQIVTARKLRDENSMLKRRDLKPVEVRDAVAATSTQILQGITRAALQTSSFMSAASFQE
TTKVLNEAAINGKTDKLEGMKENVICGHLIPAGTGQREFEKIIVGSKEEYDRILANKKTVLDYNEVE
>Mature_1426_residues
AFRKENKTKSNFSKISIGLASPEEILENSSGEVLKPETINYRTYKPERDGLFCERIFGPIKDYECHCGKYKRIRYKGIVC
DRCGVEVTEKKVRRERMGHIQLVVPVAHIWYFRSLPNKIGYLLGLPTKKLDSIIYYERYVVIQPGVKAEDGIAEYDLLSE
EEYLDILDTLPKDNQYLEDNDPNKFIAKMGAEAIYDLLARLDLDALSYELRHRAGNDASQQRKNEALKRLQVVESFRASR
GRNKPEWMIVRIVPVIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLIEIKAPEVILRNEKRMLQESVDSLFDN
SRKSSAVKTDANRPLKSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELKMGECGIPKLMAAELYKPFIIRKLIERG
IVKTVKSAKKIVDRKEAVIWDILEHVMKGHPVLLNRAPTLHRLGIQAFQPKMIEGKAIQLHPLACTAFNADFDGDQMAVH
LPLSNEAILEAQMLMLQSHNILNPANGAPITVPAQDMVLGLYYITKLRAGAKGEGLTFYGPEEALIAYNEGKVDIHAPVK
VIVKDVDENGNIVDVMRETSVGRVIVNEIVPPEAGYINTIISKKSLRDIISDVIKVCGVAKAADFLDGIKNLGYQMAFKG
GLSFNLGDIIIPKEKETLVQKGYDEVEQVVNNYNMGFITNNERYNQVIDIWTHVNSELSNILMKTISSDDQGFNSVYMML
DSGARGSKEQIRQLSGMRGLMAKLQKAGAEGGQIIENPILSNFKEGLSVLEYFISTHGARKGLADTALKTADAGYLTRRL
VDVSHDVIITEEDCGTLRGLVCTDLKNNDEVIATLYERILGRVSVHDIIHPTTGELLVAGGEEITEEVAKKIQDSPIESV
EIRSVLTCEAKKGVCAKCYGRNLATSRMVQKGEAVGVIAAQSIGEPGTQLTLRTFHAGGTAANIAANASIVAKNSARLEF
EELRTVDIVDEMGEAAKVVVGRLAEVRFVDVNTGIVLSTHNVPYGSTLYVSDGDLVEKGKLIAKWDPFNAVIITEATGKI
EFEGVIENVTYKVESDEATGLREIIIIESKDKTKVPSAHILTEDGDLIRTYNLPVGGHVIIENGQKVKAGEVIVKIPRAV
GKAGDITGGLPRVTELFEARNPSNPAVVSEIDGEVTMGKIKRGNREIIVTSKTGEVKKYLVALSKQILVQENDYVRAGTP
LSDGATTPADILAIKGPTAVQEYIVNEVQDVYRLQGVKINDKHFEIIVRQMMRKVQIDEPGDTRFLEQQVVDKLEFMEEN
DRIWGKKVVVDAGDSQNMQPGQIVTARKLRDENSMLKRRDLKPVEVRDAVAATSTQILQGITRAALQTSSFMSAASFQET
TKVLNEAAINGKTDKLEGMKENVICGHLIPAGTGQREFEKIIVGSKEEYDRILANKKTVLDYNEVE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI39725938, Length=839, Percent_Identity=26.4600715137068, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI4505939, Length=853, Percent_Identity=25.7913247362251, Blast_Score=188, Evalue=3e-47,
Organism=Homo sapiens, GI103471997, Length=224, Percent_Identity=34.375, Blast_Score=105, Evalue=3e-22,
Organism=Escherichia coli, GI2367335, Length=1426, Percent_Identity=48.5273492286115, Blast_Score=1337, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=659, Percent_Identity=26.8588770864947, Blast_Score=181, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71987878, Length=651, Percent_Identity=27.0353302611367, Blast_Score=177, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=842, Percent_Identity=23.9904988123515, Blast_Score=167, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6320061, Length=553, Percent_Identity=26.2206148282098, Blast_Score=147, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6324917, Length=261, Percent_Identity=27.5862068965517, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360912, Length=831, Percent_Identity=26.835138387485, Blast_Score=199, Evalue=1e-50,
Organism=Drosophila melanogaster, GI17530899, Length=860, Percent_Identity=26.2790697674419, Blast_Score=190, Evalue=6e-48,
Organism=Drosophila melanogaster, GI17647875, Length=335, Percent_Identity=28.955223880597, Blast_Score=114, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 158442; Mature: 158310

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFRKENKTKSNFSKISIGLASPEEILENSSGEVLKPETINYRTYKPERDGLFCERIFGP
CCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCEECCCCCCEEECCCCCCCCHHHHHHCC
IKDYECHCGKYKRIRYKGIVCDRCGVEVTEKKVRRERMGHIQLVVPVAHIWYFRSLPNKI
CCCCCCCCCCEEEEEEECEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCHHHH
GYLLGLPTKKLDSIIYYERYVVIQPGVKAEDGIAEYDLLSEEEYLDILDTLPKDNQYLED
HHEECCCHHHHHHEEEEEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCC
NDPNKFIAKMGAEAIYDLLARLDLDALSYELRHRAGNDASQQRKNEALKRLQVVESFRAS
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RGRNKPEWMIVRIVPVIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLIEIKAP
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCC
EVILRNEKRMLQESVDSLFDNSRKSSAVKTDANRPLKSLSDSLKGKQGRFRQNLLGKRVD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCC
YSARSVIVVGPELKMGECGIPKLMAAELYKPFIIRKLIERGIVKTVKSAKKIVDRKEAVI
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WDILEHVMKGHPVLLNRAPTLHRLGIQAFQPKMIEGKAIQLHPLACTAFNADFDGDQMAV
HHHHHHHHCCCCEEEECCCCHHHHCHHHCCCCEECCCEEEEEEEEEEEECCCCCCCCEEE
HLPLSNEAILEAQMLMLQSHNILNPANGAPITVPAQDMVLGLYYITKLRAGAKGEGLTFY
EECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCEEEE
GPEEALIAYNEGKVDIHAPVKVIVKDVDENGNIVDVMRETSVGRVIVNEIVPPEAGYINT
CCCCEEEEECCCCEEEECCCEEEEEECCCCCCEEEEEHHCCCCHHHHHHCCCCCCCHHHH
IISKKSLRDIISDVIKVCGVAKAADFLDGIKNLGYQMAFKGGLSFNLGDIIIPKEKETLV
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCCCEECCCCEEECCCHHHHH
QKGYDEVEQVVNNYNMGFITNNERYNQVIDIWTHVNSELSNILMKTISSDDQGFNSVYMM
HCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LDSGARGSKEQIRQLSGMRGLMAKLQKAGAEGGQIIENPILSNFKEGLSVLEYFISTHGA
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
RKGLADTALKTADAGYLTRRLVDVSHDVIITEEDCGTLRGLVCTDLKNNDEVIATLYERI
CCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCHHCCEEEECCCCCCHHHHHHHHHH
LGRVSVHDIIHPTTGELLVAGGEEITEEVAKKIQDSPIESVEIRSVLTCEAKKGVCAKCY
HCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEHHHHEEECCCCCCCHHHH
GRNLATSRMVQKGEAVGVIAAQSIGEPGTQLTLRTFHAGGTAANIAANASIVAKNSARLE
CCCHHHHHHHHCCCCEEEEEHHCCCCCCCEEEEEEEECCCCEEEHCCCCEEEECCCCCCC
FEELRTVDIVDEMGEAAKVVVGRLAEVRFVDVNTGIVLSTHNVPYGSTLYVSDGDLVEKG
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCCCEEEECCCCCHHCC
KLIAKWDPFNAVIITEATGKIEFEGVIENVTYKVESDEATGLREIIIIESKDKTKVPSAH
CEEEEECCCCEEEEEECCCCEEEEEEEECEEEEEECCCCCCCEEEEEEECCCCCCCCCCE
ILTEDGDLIRTYNLPVGGHVIIENGQKVKAGEVIVKIPRAVGKAGDITGGLPRVTELFEA
EEECCCCEEEEECCCCCCEEEEECCCEEECCCEEEEECHHHCCCCCCCCCCHHHHHHHHC
RNPSNPAVVSEIDGEVTMGKIKRGNREIIVTSKTGEVKKYLVALSKQILVQENDYVRAGT
CCCCCCCEEEECCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHEEECCCEEECCC
PLSDGATTPADILAIKGPTAVQEYIVNEVQDVYRLQGVKINDKHFEIIVRQMMRKVQIDE
CCCCCCCCCHHEEEECCCHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCC
PGDTRFLEQQVVDKLEFMEENDRIWGKKVVVDAGDSQNMQPGQIVTARKLRDENSMLKRR
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHCCHHHHHHHC
DLKPVEVRDAVAATSTQILQGITRAALQTSSFMSAASFQETTKVLNEAAINGKTDKLEGM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
KENVICGHLIPAGTGQREFEKIIVGSKEEYDRILANKKTVLDYNEVE
HHCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
AFRKENKTKSNFSKISIGLASPEEILENSSGEVLKPETINYRTYKPERDGLFCERIFGP
CCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCEECCCCCCEEECCCCCCCCHHHHHHCC
IKDYECHCGKYKRIRYKGIVCDRCGVEVTEKKVRRERMGHIQLVVPVAHIWYFRSLPNKI
CCCCCCCCCCEEEEEEECEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCHHHH
GYLLGLPTKKLDSIIYYERYVVIQPGVKAEDGIAEYDLLSEEEYLDILDTLPKDNQYLED
HHEECCCHHHHHHEEEEEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCC
NDPNKFIAKMGAEAIYDLLARLDLDALSYELRHRAGNDASQQRKNEALKRLQVVESFRAS
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RGRNKPEWMIVRIVPVIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLIEIKAP
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCC
EVILRNEKRMLQESVDSLFDNSRKSSAVKTDANRPLKSLSDSLKGKQGRFRQNLLGKRVD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCC
YSARSVIVVGPELKMGECGIPKLMAAELYKPFIIRKLIERGIVKTVKSAKKIVDRKEAVI
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WDILEHVMKGHPVLLNRAPTLHRLGIQAFQPKMIEGKAIQLHPLACTAFNADFDGDQMAV
HHHHHHHHCCCCEEEECCCCHHHHCHHHCCCCEECCCEEEEEEEEEEEECCCCCCCCEEE
HLPLSNEAILEAQMLMLQSHNILNPANGAPITVPAQDMVLGLYYITKLRAGAKGEGLTFY
EECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCEEEE
GPEEALIAYNEGKVDIHAPVKVIVKDVDENGNIVDVMRETSVGRVIVNEIVPPEAGYINT
CCCCEEEEECCCCEEEECCCEEEEEECCCCCCEEEEEHHCCCCHHHHHHCCCCCCCHHHH
IISKKSLRDIISDVIKVCGVAKAADFLDGIKNLGYQMAFKGGLSFNLGDIIIPKEKETLV
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCCCEECCCCEEECCCHHHHH
QKGYDEVEQVVNNYNMGFITNNERYNQVIDIWTHVNSELSNILMKTISSDDQGFNSVYMM
HCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LDSGARGSKEQIRQLSGMRGLMAKLQKAGAEGGQIIENPILSNFKEGLSVLEYFISTHGA
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
RKGLADTALKTADAGYLTRRLVDVSHDVIITEEDCGTLRGLVCTDLKNNDEVIATLYERI
CCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCHHCCEEEECCCCCCHHHHHHHHHH
LGRVSVHDIIHPTTGELLVAGGEEITEEVAKKIQDSPIESVEIRSVLTCEAKKGVCAKCY
HCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEHHHHEEECCCCCCCHHHH
GRNLATSRMVQKGEAVGVIAAQSIGEPGTQLTLRTFHAGGTAANIAANASIVAKNSARLE
CCCHHHHHHHHCCCCEEEEEHHCCCCCCCEEEEEEEECCCCEEEHCCCCEEEECCCCCCC
FEELRTVDIVDEMGEAAKVVVGRLAEVRFVDVNTGIVLSTHNVPYGSTLYVSDGDLVEKG
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCCCEEEECCCCCHHCC
KLIAKWDPFNAVIITEATGKIEFEGVIENVTYKVESDEATGLREIIIIESKDKTKVPSAH
CEEEEECCCCEEEEEECCCCEEEEEEEECEEEEEECCCCCCCEEEEEEECCCCCCCCCCE
ILTEDGDLIRTYNLPVGGHVIIENGQKVKAGEVIVKIPRAVGKAGDITGGLPRVTELFEA
EEECCCCEEEEECCCCCCEEEEECCCEEECCCEEEEECHHHCCCCCCCCCCHHHHHHHHC
RNPSNPAVVSEIDGEVTMGKIKRGNREIIVTSKTGEVKKYLVALSKQILVQENDYVRAGT
CCCCCCCEEEECCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHEEECCCEEECCC
PLSDGATTPADILAIKGPTAVQEYIVNEVQDVYRLQGVKINDKHFEIIVRQMMRKVQIDE
CCCCCCCCCHHEEEECCCHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCC
PGDTRFLEQQVVDKLEFMEENDRIWGKKVVVDAGDSQNMQPGQIVTARKLRDENSMLKRR
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHCCHHHHHHHC
DLKPVEVRDAVAATSTQILQGITRAALQTSSFMSAASFQETTKVLNEAAINGKTDKLEGM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
KENVICGHLIPAGTGQREFEKIIVGSKEEYDRILANKKTVLDYNEVE
HHCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA