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The map label for this gene is map [H]

Identifier: 29348115

GI number: 29348115

Start: 3367257

End: 3368054

Strand: Reverse

Name: map [H]

Synonym: BT_2706

Alternate gene names: 29348115

Gene position: 3368054-3367257 (Counterclockwise)

Preceding gene: 29348116

Following gene: 29348114

Centisome position: 53.8

GC content: 41.35

Gene sequence:

>798_bases
ATGATATTTCTTAAGACAGAAGATGAAATAGAATTGCTCCGTCAGAGTAACCTGCTTGTCGGTAGAACTCTAGCTGAGGT
TGCTAAAGTGGTGAAGCCTGGTGTAACTACACGTGAGTTGGATAAAGTTGCTGAAGAATTCATTAGAGATAATGGGGCAA
CTCCAACTTTTAAAGGATTCCCGAATCAATATGGAGACCCGTTTCCTGCATCCATCTGTACTTCTGTAAATGAGCAGGTA
GTACATGGAATCCCGGGGGATATTGTTCTGAAAGACGGCGATATCGTATCTGTGGATTGCGGAACTTATATGAATGGTTT
TTGTGGAGATTCTGCTTATACTTTTTGTGTAGGAGAGGTAGACGAAGAAATTCGTACCTTGTTGAAGGTAACTAAAGAAG
CGTTATATATCGGTATTCAGAATGCAGTACATGGAAAAAGAATCGGAGATATCGGATATGCTATTCAGCAATATTGTGAG
TCTCATTCTTATGGTGTAGTGCGTGAGTTTGTCGGTCACGGCATCGGTAAGGAAATGCACGAAGATCCCCAGGTACCTAA
TTATGGTAAAAGAGGATATGGTCCTTTGATGAAAAGAGGTCTTTGCATTGCAATTGAGCCGATGATAACGTTGGGAGACA
GACAAGTGATTATGGAAGGTGACGGATGGACTGTGAGGACCAGAGATCGTAAATGTGCTGCGCACTTTGAGCATACGGTA
GCTGTTGGAGCTGGTGAGGCTGATATTTTGTCTTCATTCAAATTCATAGAAGAAGTTTTAGGAGATAAAGCAATATAA

Upstream 100 bases:

>100_bases
TGAAAGTCATTTGTTGATGAGACATTATGATGGTCTGTTGAAATCAGGTCGTATTAAGGGACGCGCTGGTGTAGCGGCAT
ATTAATTCTTTAGAATAGAA

Downstream 100 bases:

>100_bases
TATGGCAAAGCAATCTGCAATAGAACAAGATGGAGTTATAGTTGAAGCATTGTCTAATGCAATGTTTCGTGTTGAATTAG
AAAACGGACATGAGATTACT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MIFLKTEDEIELLRQSNLLVGRTLAEVAKVVKPGVTTRELDKVAEEFIRDNGATPTFKGFPNQYGDPFPASICTSVNEQV
VHGIPGDIVLKDGDIVSVDCGTYMNGFCGDSAYTFCVGEVDEEIRTLLKVTKEALYIGIQNAVHGKRIGDIGYAIQQYCE
SHSYGVVREFVGHGIGKEMHEDPQVPNYGKRGYGPLMKRGLCIAIEPMITLGDRQVIMEGDGWTVRTRDRKCAAHFEHTV
AVGAGEADILSSFKFIEEVLGDKAI

Sequences:

>Translated_265_residues
MIFLKTEDEIELLRQSNLLVGRTLAEVAKVVKPGVTTRELDKVAEEFIRDNGATPTFKGFPNQYGDPFPASICTSVNEQV
VHGIPGDIVLKDGDIVSVDCGTYMNGFCGDSAYTFCVGEVDEEIRTLLKVTKEALYIGIQNAVHGKRIGDIGYAIQQYCE
SHSYGVVREFVGHGIGKEMHEDPQVPNYGKRGYGPLMKRGLCIAIEPMITLGDRQVIMEGDGWTVRTRDRKCAAHFEHTV
AVGAGEADILSSFKFIEEVLGDKAI
>Mature_265_residues
MIFLKTEDEIELLRQSNLLVGRTLAEVAKVVKPGVTTRELDKVAEEFIRDNGATPTFKGFPNQYGDPFPASICTSVNEQV
VHGIPGDIVLKDGDIVSVDCGTYMNGFCGDSAYTFCVGEVDEEIRTLLKVTKEALYIGIQNAVHGKRIGDIGYAIQQYCE
SHSYGVVREFVGHGIGKEMHEDPQVPNYGKRGYGPLMKRGLCIAIEPMITLGDRQVIMEGDGWTVRTRDRKCAAHFEHTV
AVGAGEADILSSFKFIEEVLGDKAI

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=250, Percent_Identity=40.4, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=36.1111111111111, Blast_Score=148, Evalue=4e-36,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=38.4313725490196, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1788728, Length=214, Percent_Identity=25.7009345794392, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=252, Percent_Identity=39.2857142857143, Blast_Score=156, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6323273, Length=252, Percent_Identity=34.9206349206349, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21355531, Length=245, Percent_Identity=39.5918367346939, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24583427, Length=248, Percent_Identity=36.6935483870968, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29121; Mature: 29121

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLKTEDEIELLRQSNLLVGRTLAEVAKVVKPGVTTRELDKVAEEFIRDNGATPTFKGF
CEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
PNQYGDPFPASICTSVNEQVVHGIPGDIVLKDGDIVSVDCGTYMNGFCGDSAYTFCVGEV
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCHHCCCCCCCCEEEEEHHH
DEEIRTLLKVTKEALYIGIQNAVHGKRIGDIGYAIQQYCESHSYGVVREFVGHGIGKEMH
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
EDPQVPNYGKRGYGPLMKRGLCIAIEPMITLGDRQVIMEGDGWTVRTRDRKCAAHFEHTV
CCCCCCCCCCCCCCHHHHCCEEEEECCEEEECCCEEEEECCCEEEEECCCHHHHHHHHHE
AVGAGEADILSSFKFIEEVLGDKAI
EECCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIFLKTEDEIELLRQSNLLVGRTLAEVAKVVKPGVTTRELDKVAEEFIRDNGATPTFKGF
CEEECCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
PNQYGDPFPASICTSVNEQVVHGIPGDIVLKDGDIVSVDCGTYMNGFCGDSAYTFCVGEV
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCHHCCCCCCCCEEEEEHHH
DEEIRTLLKVTKEALYIGIQNAVHGKRIGDIGYAIQQYCESHSYGVVREFVGHGIGKEMH
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
EDPQVPNYGKRGYGPLMKRGLCIAIEPMITLGDRQVIMEGDGWTVRTRDRKCAAHFEHTV
CCCCCCCCCCCCCCHHHHCCEEEEECCEEEECCCEEEEECCCEEEEECCCHHHHHHHHHE
AVGAGEADILSSFKFIEEVLGDKAI
EECCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]