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The map label for this gene is ltrA [H]

Identifier: 29347866

GI number: 29347866

Start: 3072048

End: 3072536

Strand: Reverse

Name: ltrA [H]

Synonym: BT_2456

Alternate gene names: 29347866

Gene position: 3072536-3072048 (Counterclockwise)

Preceding gene: 29347867

Following gene: 29347865

Centisome position: 49.08

GC content: 44.38

Gene sequence:

>489_bases
ATGCATAAAATAAGAGTCATAGAAAGTACACTTGGCTACCCTCAAAAGAATAGGATGGAATCCGAAAGCTATGAGGGAGT
GCAGACCTATATGGACATGAAAGACGGCAGTTTGATAGCAGTGCAACCAAATAAAGATGACTTAATGAGTCAAATTCTTT
CTCCCGACAATCTCAATCGTGCCTATCTACAAGTGGTACGAAACAAAGGGGTTGGAGGTGTTGATAGAATGGATTTTAAG
CAACTGCTTCCCTATCTTCATGAACACAAATCAGAACTTATCGAGTCGATACGCATTGGAAGGTACAAACCGAATTCAGT
GCGTAGGGTAGATATAGCCAAGGATAACGGGAAGAAACGGCTTATAGGCATCCCAACCGTTGTTGACCGCTTGATACAAC
AAGCCATCGTCCAAGTGCTATCGCCTATCTACGAACGCCAGTTCAGCCCAAGCAGTTTTGGGTTTCGCCCCGACGTAGTG
CGCATGTAG

Upstream 100 bases:

>100_bases
ATTGTGAGAAGTCAGCAGAAGCCATAGTACTTAAGTTCTTTTTAAGGAAGGGCTGAATCGCAATAGCTATAAACACGTAA
CTAACTCTAAATAGGAAAGA

Downstream 100 bases:

>100_bases
CATTGCTCCAAGTGTGCTGTTATACAAGCGAAGGCTACAAATATGCTGTAGGCATAGACCTTGTTAGATTCTTTGATACG
GTAAACCATAGTTTCTTACT

Product: putative reverse transcriptase/maturase

Products: NA

Alternate protein names: Reverse-transcriptase; RNA maturase; DNA endonuclease [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MHKIRVIESTLGYPQKNRMESESYEGVQTYMDMKDGSLIAVQPNKDDLMSQILSPDNLNRAYLQVVRNKGVGGVDRMDFK
QLLPYLHEHKSELIESIRIGRYKPNSVRRVDIAKDNGKKRLIGIPTVVDRLIQQAIVQVLSPIYERQFSPSSFGFRPDVV
RM

Sequences:

>Translated_162_residues
MHKIRVIESTLGYPQKNRMESESYEGVQTYMDMKDGSLIAVQPNKDDLMSQILSPDNLNRAYLQVVRNKGVGGVDRMDFK
QLLPYLHEHKSELIESIRIGRYKPNSVRRVDIAKDNGKKRLIGIPTVVDRLIQQAIVQVLSPIYERQFSPSSFGFRPDVV
RM
>Mature_162_residues
MHKIRVIESTLGYPQKNRMESESYEGVQTYMDMKDGSLIAVQPNKDDLMSQILSPDNLNRAYLQVVRNKGVGGVDRMDFK
QLLPYLHEHKSELIESIRIGRYKPNSVRRVDIAKDNGKKRLIGIPTVVDRLIQQAIVQVLSPIYERQFSPSSFGFRPDVV
RM

Specific function: Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities:reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site- specific cle

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003615
- InterPro:   IPR002866
- InterPro:   IPR000477 [H]

Pfam domain/function: PF01348 Intron_maturas2; PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 18648; Mature: 18648

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKIRVIESTLGYPQKNRMESESYEGVQTYMDMKDGSLIAVQPNKDDLMSQILSPDNLNR
CCCEEEEHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCH
AYLQVVRNKGVGGVDRMDFKQLLPYLHEHKSELIESIRIGRYKPNSVRRVDIAKDNGKKR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEE
LIGIPTVVDRLIQQAIVQVLSPIYERQFSPSSFGFRPDVVRM
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHKIRVIESTLGYPQKNRMESESYEGVQTYMDMKDGSLIAVQPNKDDLMSQILSPDNLNR
CCCEEEEHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCH
AYLQVVRNKGVGGVDRMDFKQLLPYLHEHKSELIESIRIGRYKPNSVRRVDIAKDNGKKR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEE
LIGIPTVVDRLIQQAIVQVLSPIYERQFSPSSFGFRPDVVRM
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655550; 11157264; 10488339; 9353259; 10413481; 11731786 [H]