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The map label for this gene is idsA [H]

Identifier: 29347468

GI number: 29347468

Start: 2577222

End: 2578196

Strand: Reverse

Name: idsA [H]

Synonym: BT_2058

Alternate gene names: 29347468

Gene position: 2578196-2577222 (Counterclockwise)

Preceding gene: 29347469

Following gene: 29347467

Centisome position: 41.18

GC content: 43.59

Gene sequence:

>975_bases
ATGTTTACAGCTTCTCAATTACTTGATAAAATAAACAACCACCTATCTGAAATTCAGATAACCCGGACTCCGGAAGGACT
CTACGAACCAATCGAATACATCCTTTCTCTGGGAGGAAAGCGGATTCGTCCTGTATTGATGCTGATGGCATATAACTTGT
ATAAGGAAGATGTTTCATCAATTTACGATCCTGCTACCGGTATCGAAGTTTATCATAATCACACTTTGTTGCATGATGAT
CTGATGGATCGTTCGGATATGCGCAGAGGAAAACCGACTGTGCATAAGGTCTGGAACGATAACACAGCTATTTTGTCGGG
TGATACCATGCTGATACTGGCTTTCCGGTATGTAGCCGGTTGTGCGCCCGAGCATTTGAAAGAAGTCATTGATTTGTTTA
GTCTGACTGCGTTGGAAATTTGTGAAGGGCAGCAGTTGGATATGGAATTTGAGTCGCGCAACGATGTGGCGGAAGACGAA
TATATTGAAATGATTCGTCTGAAAACGGCTGTATTGCTTGCCGCAAGTCTGAAGATCGGTGCGATTCTGGCAGGAGCGTC
TGCCGCTGATGCGGAGAATCTTTATAATTTTGGTATGCAGATAGGGGTTGCATTCCAGTTACAGGATGATTTGCTGGATG
TTTATGGCGATCCGGAAGTGTTCGGAAAGAAAATCGGTGGAGACATCCTTTGCAATAAGAAGACATATATGCTGATCAAA
GCACTGGAACGTGCAAACGGAGAACAGCTGGAAGAACTGAATCGCTGGCTGAATGCAGACAACTGTCAGCCGGCAGAAAA
GATAGCGGCAGTGACGGAGATTTATAATCAGTTGACTATCCGCAGCGTTTGTGAAAACAAAATGCGCGAATATTATACGC
TGGCTATGGAGAGTCTTGAAGCAGTTGCAGTTGCAGAAGAGAAGAAGAAAGAACTTAAGAATTTAGTGAAATTACTGATG
TATCGGGAAATGTAG

Upstream 100 bases:

>100_bases
ACAGTTCCTGTAATGTTCAGATTGCAGTAATTTGTAACACTCATACATTTAAGAGGCTGCGAATGCAGCCTCTTTTTATT
CATTAATCTTTGTTTTCATC

Downstream 100 bases:

>100_bases
TAAAGTTGGTGGGAAATGCCTTACAGACGATTGCCAAATACGGATCAAGCCAGAGTACGGGCGCTGAAAGCAGCGGTCGA
GAAGGGTGACGTGTATAATG

Product: putative isoprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MFTASQLLDKINNHLSEIQITRTPEGLYEPIEYILSLGGKRIRPVLMLMAYNLYKEDVSSIYDPATGIEVYHNHTLLHDD
LMDRSDMRRGKPTVHKVWNDNTAILSGDTMLILAFRYVAGCAPEHLKEVIDLFSLTALEICEGQQLDMEFESRNDVAEDE
YIEMIRLKTAVLLAASLKIGAILAGASAADAENLYNFGMQIGVAFQLQDDLLDVYGDPEVFGKKIGGDILCNKKTYMLIK
ALERANGEQLEELNRWLNADNCQPAEKIAAVTEIYNQLTIRSVCENKMREYYTLAMESLEAVAVAEEKKKELKNLVKLLM
YREM

Sequences:

>Translated_324_residues
MFTASQLLDKINNHLSEIQITRTPEGLYEPIEYILSLGGKRIRPVLMLMAYNLYKEDVSSIYDPATGIEVYHNHTLLHDD
LMDRSDMRRGKPTVHKVWNDNTAILSGDTMLILAFRYVAGCAPEHLKEVIDLFSLTALEICEGQQLDMEFESRNDVAEDE
YIEMIRLKTAVLLAASLKIGAILAGASAADAENLYNFGMQIGVAFQLQDDLLDVYGDPEVFGKKIGGDILCNKKTYMLIK
ALERANGEQLEELNRWLNADNCQPAEKIAAVTEIYNQLTIRSVCENKMREYYTLAMESLEAVAVAEEKKKELKNLVKLLM
YREM
>Mature_324_residues
MFTASQLLDKINNHLSEIQITRTPEGLYEPIEYILSLGGKRIRPVLMLMAYNLYKEDVSSIYDPATGIEVYHNHTLLHDD
LMDRSDMRRGKPTVHKVWNDNTAILSGDTMLILAFRYVAGCAPEHLKEVIDLFSLTALEICEGQQLDMEFESRNDVAEDE
YIEMIRLKTAVLLAASLKIGAILAGASAADAENLYNFGMQIGVAFQLQDDLLDVYGDPEVFGKKIGGDILCNKKTYMLIK
ALERANGEQLEELNRWLNADNCQPAEKIAAVTEIYNQLTIRSVCENKMREYYTLAMESLEAVAVAEEKKKELKNLVKLLM
YREM

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=235, Percent_Identity=29.3617021276596, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI209571584, Length=300, Percent_Identity=28.6666666666667, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI209571582, Length=291, Percent_Identity=28.5223367697594, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4503685, Length=291, Percent_Identity=28.5223367697594, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4758430, Length=234, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI83700220, Length=234, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1789578, Length=219, Percent_Identity=36.5296803652968, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786623, Length=246, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17505681, Length=256, Percent_Identity=27.34375, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17508563, Length=241, Percent_Identity=26.5560165975104, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322294, Length=229, Percent_Identity=29.2576419213974, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325188, Length=241, Percent_Identity=24.896265560166, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24651612, Length=221, Percent_Identity=31.6742081447964, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17137582, Length=262, Percent_Identity=30.5343511450382, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 36716; Mature: 36716

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTASQLLDKINNHLSEIQITRTPEGLYEPIEYILSLGGKRIRPVLMLMAYNLYKEDVSS
CCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IYDPATGIEVYHNHTLLHDDLMDRSDMRRGKPTVHKVWNDNTAILSGDTMLILAFRYVAG
HHCCCCCCEECCCCEEEHHHHHCHHHHHCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHC
CAPEHLKEVIDLFSLTALEICEGQQLDMEFESRNDVAEDEYIEMIRLKTAVLLAASLKIG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILAGASAADAENLYNFGMQIGVAFQLQDDLLDVYGDPEVFGKKIGGDILCNKKTYMLIK
HHEECCCCCCHHHHHHHHHHHEEEEEEHHHHHHHCCCHHHHHHHCCCCEEECCHHHHHHH
ALERANGEQLEELNRWLNADNCQPAEKIAAVTEIYNQLTIRSVCENKMREYYTLAMESLE
HHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAVAEEKKKELKNLVKLLMYREM
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTASQLLDKINNHLSEIQITRTPEGLYEPIEYILSLGGKRIRPVLMLMAYNLYKEDVSS
CCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IYDPATGIEVYHNHTLLHDDLMDRSDMRRGKPTVHKVWNDNTAILSGDTMLILAFRYVAG
HHCCCCCCEECCCCEEEHHHHHCHHHHHCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHC
CAPEHLKEVIDLFSLTALEICEGQQLDMEFESRNDVAEDEYIEMIRLKTAVLLAASLKIG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILAGASAADAENLYNFGMQIGVAFQLQDDLLDVYGDPEVFGKKIGGDILCNKKTYMLIK
HHEECCCCCCHHHHHHHHHHHEEEEEEHHHHHHHCCCHHHHHHHCCCCEEECCHHHHHHH
ALERANGEQLEELNRWLNADNCQPAEKIAAVTEIYNQLTIRSVCENKMREYYTLAMESLE
HHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAVAEEKKKELKNLVKLLMYREM
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]