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The map label for this gene is cusC [H]

Identifier: 29347375

GI number: 29347375

Start: 2465318

End: 2466688

Strand: Reverse

Name: cusC [H]

Synonym: BT_1965

Alternate gene names: 29347375

Gene position: 2466688-2465318 (Counterclockwise)

Preceding gene: 29347376

Following gene: 29347374

Centisome position: 39.4

GC content: 50.77

Gene sequence:

>1371_bases
ATGATGAAGAAAATATTAATCTTATCCGCAGCAACGCTCGTGTTGAGTAGTTGCGGTATCTACAATAAATACAAACCTGT
ATCGGAAGTCCCCGAAGGACTTTATGGAAGCGAGACCGTCGCTTCCGCCGATACGGCGAACTTCGGTAATCTCTCGTGGA
GAGAGGTCTTTACTGACTCGTATTTGCAGAATTTGATCGATTCGGCTTTGGTACGGAATACGGATATGCAGACAGCGCAT
CTCCGTGTGAAAGAAGCGGAGGCTTCGTTGCTGACGTCCAAGCTTTCTTATCTGCCCTCTTTGTTTCTCGCACCGGAAGG
AGCTGTGAGCAGCTTCGACCGTGGCAAAGCGACACAGACCTACTCATTGCCGGTGACTGCCTCGTGGGAACTGGATATCT
TCGGAAAGGTGACCACGGCCAAACGTCGGGCAAAAGCGGCCTATGAGCAGAGCAAGGAGTATGAACAGGCGGTGAAGACG
CAATTGGTGTCTGCCGTGGCGAATACTTATTATACCTTGCTGATGCTCGACGCTCAATATGAGATTTCCGTGTCCACCGA
AGCGGCATGGAAAGAGAGCGTGCGGACAGCCCGTGCCATGAAGAAGGCCGGTATGATGACCGAAGCCGGACTGGCTCAGA
CGGAAGCTACCTATTATAATATATGTACGACAGTGCTCGACCTGAAAGAACAAATCAATCAGACCGAGAACTCAATGGCT
TTGTTGCTGGCGGAAACACCTCACAAGATGCAACGCGGCAAACTGGAAAACCAGCAGTTGCCGGAAGACTTCTCCGTAGG
GATTCCTTTGCAGATGCTTTCCAACCGTCCGGATGTACGTAGCGCGGAGTTCTCTTTAGCGCAGGCGTTCTATACGACGA
ATGCTGCCCGTGCCGCTTTCTATCCTTCCATCACGCTGAGCGGGAGTGCCGGATGGACAAACAGTGCCGGTAGCATGATT
ATCAATCCGGGCAAGTTTGTTGCTTCTGCCGTAGCTTCACTGACGCAACCTTTATTTAACAAGGGAGTGAATATCGCCCA
GCTGAAAATAGCGAAGGCACAGCAGGAAGAAGCCCGCCTCAGCTTTGAACAGACATTGCTGAACGCAGGTGTGGAAGTAA
ACGAGGCACTGGTGCAATATCAGACGGCCCGTGAGAAATCCGCTTTCTACGATAAGCAGATCACCTCTTTGCAGACTGCT
GCCAGAAGCACTAGTCTTTTGATGGAACATAGTAATAATACTACTTATCTGGAAGTACTGACCGCACAGCAGACATTGCT
GAACGCCAGACTTTCACAGGTAGCCAATCGCTTTACCGAAATCCAGGGCGTGATTACACTGTATCAGGCTTTGGGCGGAG
GCCGGATGTAG

Upstream 100 bases:

>100_bases
CTTACGCCCTGTGCAGAGCAGACCTACGGAAGACTGGCAGATCGAGGAAGAAATCAAGGTGAGTGAAGAAGAAAAATCTA
AAGCAGGAAAAAAATAATTG

Downstream 100 bases:

>100_bases
GAGGATAGTATGAATCCTGAAAAAGTACGGTGTCAGATAATCGAATACACCAAACACGAGATGTATCTGCACGGTGCTGA
CGGACTGACCATGGATGACA

Product: multidrug efflux pump channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MMKKILILSAATLVLSSCGIYNKYKPVSEVPEGLYGSETVASADTANFGNLSWREVFTDSYLQNLIDSALVRNTDMQTAH
LRVKEAEASLLTSKLSYLPSLFLAPEGAVSSFDRGKATQTYSLPVTASWELDIFGKVTTAKRRAKAAYEQSKEYEQAVKT
QLVSAVANTYYTLLMLDAQYEISVSTEAAWKESVRTARAMKKAGMMTEAGLAQTEATYYNICTTVLDLKEQINQTENSMA
LLLAETPHKMQRGKLENQQLPEDFSVGIPLQMLSNRPDVRSAEFSLAQAFYTTNAARAAFYPSITLSGSAGWTNSAGSMI
INPGKFVASAVASLTQPLFNKGVNIAQLKIAKAQQEEARLSFEQTLLNAGVEVNEALVQYQTAREKSAFYDKQITSLQTA
ARSTSLLMEHSNNTTYLEVLTAQQTLLNARLSQVANRFTEIQGVITLYQALGGGRM

Sequences:

>Translated_456_residues
MMKKILILSAATLVLSSCGIYNKYKPVSEVPEGLYGSETVASADTANFGNLSWREVFTDSYLQNLIDSALVRNTDMQTAH
LRVKEAEASLLTSKLSYLPSLFLAPEGAVSSFDRGKATQTYSLPVTASWELDIFGKVTTAKRRAKAAYEQSKEYEQAVKT
QLVSAVANTYYTLLMLDAQYEISVSTEAAWKESVRTARAMKKAGMMTEAGLAQTEATYYNICTTVLDLKEQINQTENSMA
LLLAETPHKMQRGKLENQQLPEDFSVGIPLQMLSNRPDVRSAEFSLAQAFYTTNAARAAFYPSITLSGSAGWTNSAGSMI
INPGKFVASAVASLTQPLFNKGVNIAQLKIAKAQQEEARLSFEQTLLNAGVEVNEALVQYQTAREKSAFYDKQITSLQTA
ARSTSLLMEHSNNTTYLEVLTAQQTLLNARLSQVANRFTEIQGVITLYQALGGGRM
>Mature_456_residues
MMKKILILSAATLVLSSCGIYNKYKPVSEVPEGLYGSETVASADTANFGNLSWREVFTDSYLQNLIDSALVRNTDMQTAH
LRVKEAEASLLTSKLSYLPSLFLAPEGAVSSFDRGKATQTYSLPVTASWELDIFGKVTTAKRRAKAAYEQSKEYEQAVKT
QLVSAVANTYYTLLMLDAQYEISVSTEAAWKESVRTARAMKKAGMMTEAGLAQTEATYYNICTTVLDLKEQINQTENSMA
LLLAETPHKMQRGKLENQQLPEDFSVGIPLQMLSNRPDVRSAEFSLAQAFYTTNAARAAFYPSITLSGSAGWTNSAGSMI
INPGKFVASAVASLTQPLFNKGVNIAQLKIAKAQQEEARLSFEQTLLNAGVEVNEALVQYQTAREKSAFYDKQITSLQTA
ARSTSLLMEHSNNTTYLEVLTAQQTLLNARLSQVANRFTEIQGVITLYQALGGGRM

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=461, Percent_Identity=29.5010845986985, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50030; Mature: 50030

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKILILSAATLVLSSCGIYNKYKPVSEVPEGLYGSETVASADTANFGNLSWREVFTDS
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHH
YLQNLIDSALVRNTDMQTAHLRVKEAEASLLTSKLSYLPSLFLAPEGAVSSFDRGKATQT
HHHHHHHHHHHCCCCCCHHHEEEHHHHHHHHHHHHHHCCHHHCCCCCCHHCCCCCCCCEE
YSLPVTASWELDIFGKVTTAKRRAKAAYEQSKEYEQAVKTQLVSAVANTYYTLLMLDAQY
EECCEEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCE
EISVSTEAAWKESVRTARAMKKAGMMTEAGLAQTEATYYNICTTVLDLKEQINQTENSMA
EEEECHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LLLAETPHKMQRGKLENQQLPEDFSVGIPLQMLSNRPDVRSAEFSLAQAFYTTNAARAAF
EEEECCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCHHHEE
YPSITLSGSAGWTNSAGSMIINPGKFVASAVASLTQPLFNKGVNIAQLKIAKAQQEEARL
CCCEEECCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
SFEQTLLNAGVEVNEALVQYQTAREKSAFYDKQITSLQTAARSTSLLMEHSNNTTYLEVL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEH
TAQQTLLNARLSQVANRFTEIQGVITLYQALGGGRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMKKILILSAATLVLSSCGIYNKYKPVSEVPEGLYGSETVASADTANFGNLSWREVFTDS
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHH
YLQNLIDSALVRNTDMQTAHLRVKEAEASLLTSKLSYLPSLFLAPEGAVSSFDRGKATQT
HHHHHHHHHHHCCCCCCHHHEEEHHHHHHHHHHHHHHCCHHHCCCCCCHHCCCCCCCCEE
YSLPVTASWELDIFGKVTTAKRRAKAAYEQSKEYEQAVKTQLVSAVANTYYTLLMLDAQY
EECCEEEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCE
EISVSTEAAWKESVRTARAMKKAGMMTEAGLAQTEATYYNICTTVLDLKEQINQTENSMA
EEEECHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LLLAETPHKMQRGKLENQQLPEDFSVGIPLQMLSNRPDVRSAEFSLAQAFYTTNAARAAF
EEEECCCHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCHHHEE
YPSITLSGSAGWTNSAGSMIINPGKFVASAVASLTQPLFNKGVNIAQLKIAKAQQEEARL
CCCEEECCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
SFEQTLLNAGVEVNEALVQYQTAREKSAFYDKQITSLQTAARSTSLLMEHSNNTTYLEVL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEH
TAQQTLLNARLSQVANRFTEIQGVITLYQALGGGRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]