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The map label for this gene is ltaE [H]

Identifier: 29347225

GI number: 29347225

Start: 2277969

End: 2278982

Strand: Reverse

Name: ltaE [H]

Synonym: BT_1815

Alternate gene names: 29347225

Gene position: 2278982-2277969 (Counterclockwise)

Preceding gene: 29347226

Following gene: 29347224

Centisome position: 36.4

GC content: 47.93

Gene sequence:

>1014_bases
ATGAGAAGTTTTGCCTCTGATAATAATTCCGGTGTGCATCCGTTGGTGATGGAAGCATTGAGCCGGGCAAACGCAGATCA
TGCGTTGGGTTATGGTGATGATCGATGGACGGAAGAAGCCGTAGCCAAGATAAAAGAAACCTTTACACAGGACTGTGTCC
CTTTGTTTGTATTCAATGGCACGGGCAGCAATGTGGTGGCTTTGCAAGTAATGACGCGTCCGTATCATTCAATCTTCTGT
GCAGAAACTGCCCATATTTATGTAGACGAGTGCGGCTCTCCCGTGAAAATGACAGGTTGTCAGATTCGGCCGATTGCCAC
AACCGATGGTAAGTTGACTCCCGAACTGATGCAGCCTTATCTGCACGGTTTCGGCGACCAGCATCATTCGCAACCCCGTG
CGCTTTACATCTCTCAATGCACCGAACTCGGAACGATTTATACACCCGAAGAACTGAAACGTCTGACTGACTTTGCCCAT
CTGAACGGTATGTATGTCCACATGGACGGAGCAAGGATTGCCAATGCCTGTGCCGCTCTTCATCTTTCGCTCAAAGAACT
GACTGTAGACTGTGGAATTGACATCCTTAGTTTCGGCGGAACAAAAAACGGACTGATGATGGGGGAATGTGTGATTATAT
TTAATAAGGACCTGCAACGGGAAGCCCGTTTTGTCCGGAAACAATCTGCCCAACTGGCTTCCAAGATGCGTTACCTTTCC
TGTCAGTTTACTACCTACTTGACGGATGACCTGTGGCTGAAGAATGCCGCTCATGCCAATGCGATGGCAGGCAAGCTCTA
TCGGGCACTTAAGGAACTGCCCGAAGTCACCTTTACCCAAAAGCCGGAGAGCAACCAGTTATTTCTGACCATGCCCCGTC
CGACTATCGACCGGATGCTGGAATCTTATTTCTTTTATTTCTGGAATGAGGCGAATCACGAAATCCGCCTGGTGACTTCT
TTTGACACAACGGAAGAGGATGTAAATCAATTTATTCGACTTTTGAGACGTTAA

Upstream 100 bases:

>100_bases
TTGCTCGGATTAGATTATTGGCTGCGCAAGAAGTATATCTGGAAATAATTCTGTTACTTTGCATGACAATTAAAACAATG
CGAAGAAACAAGAAGAAACA

Downstream 100 bases:

>100_bases
AGGAGAAGAATGGAACAACAAAAGCGTCTATAATACTGTTGTAATAGGAAGTTTGGGGCTAACTTTGTCCCCGTAATATT
GCTTCTTGTTATGATGGATG

Product: low-specificity L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRSFASDNNSGVHPLVMEALSRANADHALGYGDDRWTEEAVAKIKETFTQDCVPLFVFNGTGSNVVALQVMTRPYHSIFC
AETAHIYVDECGSPVKMTGCQIRPIATTDGKLTPELMQPYLHGFGDQHHSQPRALYISQCTELGTIYTPEELKRLTDFAH
LNGMYVHMDGARIANACAALHLSLKELTVDCGIDILSFGGTKNGLMMGECVIIFNKDLQREARFVRKQSAQLASKMRYLS
CQFTTYLTDDLWLKNAAHANAMAGKLYRALKELPEVTFTQKPESNQLFLTMPRPTIDRMLESYFFYFWNEANHEIRLVTS
FDTTEEDVNQFIRLLRR

Sequences:

>Translated_337_residues
MRSFASDNNSGVHPLVMEALSRANADHALGYGDDRWTEEAVAKIKETFTQDCVPLFVFNGTGSNVVALQVMTRPYHSIFC
AETAHIYVDECGSPVKMTGCQIRPIATTDGKLTPELMQPYLHGFGDQHHSQPRALYISQCTELGTIYTPEELKRLTDFAH
LNGMYVHMDGARIANACAALHLSLKELTVDCGIDILSFGGTKNGLMMGECVIIFNKDLQREARFVRKQSAQLASKMRYLS
CQFTTYLTDDLWLKNAAHANAMAGKLYRALKELPEVTFTQKPESNQLFLTMPRPTIDRMLESYFFYFWNEANHEIRLVTS
FDTTEEDVNQFIRLLRR
>Mature_337_residues
MRSFASDNNSGVHPLVMEALSRANADHALGYGDDRWTEEAVAKIKETFTQDCVPLFVFNGTGSNVVALQVMTRPYHSIFC
AETAHIYVDECGSPVKMTGCQIRPIATTDGKLTPELMQPYLHGFGDQHHSQPRALYISQCTELGTIYTPEELKRLTDFAH
LNGMYVHMDGARIANACAALHLSLKELTVDCGIDILSFGGTKNGLMMGECVIIFNKDLQREARFVRKQSAQLASKMRYLS
CQFTTYLTDDLWLKNAAHANAMAGKLYRALKELPEVTFTQKPESNQLFLTMPRPTIDRMLESYFFYFWNEANHEIRLVTS
FDTTEEDVNQFIRLLRR

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=293, Percent_Identity=27.3037542662116, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 38190; Mature: 38190

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFASDNNSGVHPLVMEALSRANADHALGYGDDRWTEEAVAKIKETFTQDCVPLFVFNG
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
TGSNVVALQVMTRPYHSIFCAETAHIYVDECGSPVKMTGCQIRPIATTDGKLTPELMQPY
CCCCEEEEEEECCCCHHEEEECCCEEEEECCCCCEEECCEEEEEEECCCCCCCHHHHHHH
LHGFGDQHHSQPRALYISQCTELGTIYTPEELKRLTDFAHLNGMYVHMDGARIANACAAL
HHCCCCCCCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHH
HLSLKELTVDCGIDILSFGGTKNGLMMGECVIIFNKDLQREARFVRKQSAQLASKMRYLS
HHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHE
CQFTTYLTDDLWLKNAAHANAMAGKLYRALKELPEVTFTQKPESNQLFLTMPRPTIDRML
EEEEEEECHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEEECCHHHHHHH
ESYFFYFWNEANHEIRLVTSFDTTEEDVNQFIRLLRR
HHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRSFASDNNSGVHPLVMEALSRANADHALGYGDDRWTEEAVAKIKETFTQDCVPLFVFNG
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
TGSNVVALQVMTRPYHSIFCAETAHIYVDECGSPVKMTGCQIRPIATTDGKLTPELMQPY
CCCCEEEEEEECCCCHHEEEECCCEEEEECCCCCEEECCEEEEEEECCCCCCCHHHHHHH
LHGFGDQHHSQPRALYISQCTELGTIYTPEELKRLTDFAHLNGMYVHMDGARIANACAAL
HHCCCCCCCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHH
HLSLKELTVDCGIDILSFGGTKNGLMMGECVIIFNKDLQREARFVRKQSAQLASKMRYLS
HHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHE
CQFTTYLTDDLWLKNAAHANAMAGKLYRALKELPEVTFTQKPESNQLFLTMPRPTIDRML
EEEEEEECHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEEECCHHHHHHH
ESYFFYFWNEANHEIRLVTSFDTTEEDVNQFIRLLRR
HHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]