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The map label for this gene is luxQ [H]

Identifier: 29347148

GI number: 29347148

Start: 2142214

End: 2144133

Strand: Reverse

Name: luxQ [H]

Synonym: BT_1738

Alternate gene names: 29347148

Gene position: 2144133-2142214 (Counterclockwise)

Preceding gene: 29347150

Following gene: 29347147

Centisome position: 34.25

GC content: 44.27

Gene sequence:

>1920_bases
ATGGTTATTAGCTTATTCATTCTGTGTTTTGCATCTACTTTAGCCTTTAGTAGCACAAACAAAGAAAAACAGTTGGAAGC
CCTTTCCGACAGTGTCTCAAATAAAATAGGTCAGAAAGATTTTATACCTTTCTATCAGGAATATATGCGATTGGCAAGGC
AGCAGAATGATACTGCTAAAATCGACGATGCTTATTCTCAGATTGCTTCCCATTATTACCGGTTGAGAAATACGGATAGC
CTGAAAGTGGTTGCATATGAATATATGGACTGGTGCCTGAAGCGTGGTAATATCAATAATCGCTATACGCAGTGGCGCCA
GTATATTCAGTTGCTTACCGAGAAAGGTTTGCAGGATGAGGCCATGCGTGAGACTGGACTTCTTCAGAAGGATGCGGATG
CGGCCAAAAGTGCTTTCGGAATGGCTTGCAGCGAGATGTGTATCGGATATAATCATCGGGTGTTCAGCAACAACGTCAAG
CTCTGTCTTGAATACTATTCTTCCGCACTGAAAAAATTTAGTGATGCGGGTTTTTATGAAGATGCCTATGTGGTGTCACT
GAATATCATCCAGACTTATCTGGCTAGAGGGGAGTATGCCAATGCGATGGAATACTTGAACCGTATGCCGGGACTGATTG
AGAAAATGAAGCGTAAGGATATCCCTGTCCGACCGGAGCTTACCATGCGTTATTATCAGTTTCAAGTGATTGCTACGCTG
GCATTGAAAGGGAAGAAGGAGGCGCAACCGTTTATTGCAGAAGCGGATAAGTTTTATCACGAAAATATGAATGCTTTTCC
CCGTGAAGGATGGTTGGGATATAAAATTCTTTGTGCGCGGACGTTGAATGACAATCAGATGGCACTCAACTATCTGGACT
CATTGATGGATTATCATCATTCGGTGGGGAGCTGTTATCCTGCCAATCACCTGTTGAAAGCCCAGTTTATGGAGCAGATG
GGACGCTTTGAAGATGCCTGCGAGGTTTATAAATCTTATGCGCATATTAATGATTCCATTCGTTCGGCAGAGCTGGACGA
GCAATTAAGCAAATATACTGTGCAATTCGAAGTGGACAAGCTGGAGCACGATAAGCTGGAATTGCGGGCGGAGGTCAACC
GCAATCTCTTTATAACTTCCGTGATTGTCGGATGCCTGGTGTTGATATTGTTGATTGTTATCACGTTCTACTATATGCGC
TCCTTGTCGTTGAACCGGAAACTGGATGCGGCAAATAAGGCCGTTATCAAGGCCAGCCATATGAAAAGCTCTTTTATCCA
GCATATCACACATGAAATCCGTACTCCGCTCAATTCGATTATCGGTTTTTCATCCTTGATGGCTGCCGGTGGGCTGACAC
AGGAAGAGATGGAAGAATATGCCCGTCAGATGGAGAGCAGCAACGCATATCTGCTTGATTTGGTAAATAATGTGATTGAT
ATAGCCGACATGGACTCTCAGACGGATGATATACCGAAGAAGCCAGTGAGTGTAGATGCGTGTTGTCAGGAATGTTTAGG
ATTGATTCGTCAGAATCTGAAAGAAGGAATCAAGTTGCAATATATGCCTTCTTCCACTCCGGTCGAAGTGTGTACGGTTG
AAATCTGGATGAAGCGTGTGCTACTCGGTTTGCTGAACAATGCCAATAAATTCACGGAAACCGGATTTATACGTCTGAGT
TATGAAGAAGACAAACCGAATCGTCTGGTACGTTTCATTATCGAAGATTCCGGTCCCGGAATTGAAGAGCACTTTCGGGA
TGCGATTTTCGAACGCTTTGCAAAGGCGGATACCTTCACTCAGGGCACCGGGCTGGGATTGTCTATTATCCGTCAGATCA
TGGAATTAGTGGATGGAAATGTCTATCTGGACACCAGCTACGCGGGTGGTGCAAGATTTGTTGTCGAATGGCCTCAATAA

Upstream 100 bases:

>100_bases
AAAGAAATTGCTTCGGGATAATTGGCGTATCTTGGTCCGGAATTTACAACAAACATTTCAAAATAATAACAAATTGACTT
GAATCGTGAAAAACATCCGG

Downstream 100 bases:

>100_bases
TAGTTGGAGATAGTATCTGCATCTATTATCTTTGCACCACATTATTTTATGACTCAAGAACATTATGAATCTGAAAAACT
ATCTTTTCTTATTAGTTCTG

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MVISLFILCFASTLAFSSTNKEKQLEALSDSVSNKIGQKDFIPFYQEYMRLARQQNDTAKIDDAYSQIASHYYRLRNTDS
LKVVAYEYMDWCLKRGNINNRYTQWRQYIQLLTEKGLQDEAMRETGLLQKDADAAKSAFGMACSEMCIGYNHRVFSNNVK
LCLEYYSSALKKFSDAGFYEDAYVVSLNIIQTYLARGEYANAMEYLNRMPGLIEKMKRKDIPVRPELTMRYYQFQVIATL
ALKGKKEAQPFIAEADKFYHENMNAFPREGWLGYKILCARTLNDNQMALNYLDSLMDYHHSVGSCYPANHLLKAQFMEQM
GRFEDACEVYKSYAHINDSIRSAELDEQLSKYTVQFEVDKLEHDKLELRAEVNRNLFITSVIVGCLVLILLIVITFYYMR
SLSLNRKLDAANKAVIKASHMKSSFIQHITHEIRTPLNSIIGFSSLMAAGGLTQEEMEEYARQMESSNAYLLDLVNNVID
IADMDSQTDDIPKKPVSVDACCQECLGLIRQNLKEGIKLQYMPSSTPVEVCTVEIWMKRVLLGLLNNANKFTETGFIRLS
YEEDKPNRLVRFIIEDSGPGIEEHFRDAIFERFAKADTFTQGTGLGLSIIRQIMELVDGNVYLDTSYAGGARFVVEWPQ

Sequences:

>Translated_639_residues
MVISLFILCFASTLAFSSTNKEKQLEALSDSVSNKIGQKDFIPFYQEYMRLARQQNDTAKIDDAYSQIASHYYRLRNTDS
LKVVAYEYMDWCLKRGNINNRYTQWRQYIQLLTEKGLQDEAMRETGLLQKDADAAKSAFGMACSEMCIGYNHRVFSNNVK
LCLEYYSSALKKFSDAGFYEDAYVVSLNIIQTYLARGEYANAMEYLNRMPGLIEKMKRKDIPVRPELTMRYYQFQVIATL
ALKGKKEAQPFIAEADKFYHENMNAFPREGWLGYKILCARTLNDNQMALNYLDSLMDYHHSVGSCYPANHLLKAQFMEQM
GRFEDACEVYKSYAHINDSIRSAELDEQLSKYTVQFEVDKLEHDKLELRAEVNRNLFITSVIVGCLVLILLIVITFYYMR
SLSLNRKLDAANKAVIKASHMKSSFIQHITHEIRTPLNSIIGFSSLMAAGGLTQEEMEEYARQMESSNAYLLDLVNNVID
IADMDSQTDDIPKKPVSVDACCQECLGLIRQNLKEGIKLQYMPSSTPVEVCTVEIWMKRVLLGLLNNANKFTETGFIRLS
YEEDKPNRLVRFIIEDSGPGIEEHFRDAIFERFAKADTFTQGTGLGLSIIRQIMELVDGNVYLDTSYAGGARFVVEWPQ
>Mature_639_residues
MVISLFILCFASTLAFSSTNKEKQLEALSDSVSNKIGQKDFIPFYQEYMRLARQQNDTAKIDDAYSQIASHYYRLRNTDS
LKVVAYEYMDWCLKRGNINNRYTQWRQYIQLLTEKGLQDEAMRETGLLQKDADAAKSAFGMACSEMCIGYNHRVFSNNVK
LCLEYYSSALKKFSDAGFYEDAYVVSLNIIQTYLARGEYANAMEYLNRMPGLIEKMKRKDIPVRPELTMRYYQFQVIATL
ALKGKKEAQPFIAEADKFYHENMNAFPREGWLGYKILCARTLNDNQMALNYLDSLMDYHHSVGSCYPANHLLKAQFMEQM
GRFEDACEVYKSYAHINDSIRSAELDEQLSKYTVQFEVDKLEHDKLELRAEVNRNLFITSVIVGCLVLILLIVITFYYMR
SLSLNRKLDAANKAVIKASHMKSSFIQHITHEIRTPLNSIIGFSSLMAAGGLTQEEMEEYARQMESSNAYLLDLVNNVID
IADMDSQTDDIPKKPVSVDACCQECLGLIRQNLKEGIKLQYMPSSTPVEVCTVEIWMKRVLLGLLNNANKFTETGFIRLS
YEEDKPNRLVRFIIEDSGPGIEEHFRDAIFERFAKADTFTQGTGLGLSIIRQIMELVDGNVYLDTSYAGGARFVVEWPQ

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=29.004329004329, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=30.0847457627119, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=28.1512605042017, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=28.8135593220339, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=27.8761061946903, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=25.968992248062, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=26.7543859649123, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=28.8793103448276, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=268, Percent_Identity=25.7462686567164, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786783, Length=301, Percent_Identity=24.9169435215947, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1789808, Length=232, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790861, Length=211, Percent_Identity=28.436018957346, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73336; Mature: 73336

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVISLFILCFASTLAFSSTNKEKQLEALSDSVSNKIGQKDFIPFYQEYMRLARQQNDTAK
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCH
IDDAYSQIASHYYRLRNTDSLKVVAYEYMDWCLKRGNINNRYTQWRQYIQLLTEKGLQDE
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHH
AMRETGLLQKDADAAKSAFGMACSEMCIGYNHRVFSNNVKLCLEYYSSALKKFSDAGFYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCC
DAYVVSLNIIQTYLARGEYANAMEYLNRMPGLIEKMKRKDIPVRPELTMRYYQFQVIATL
CHHEEHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ALKGKKEAQPFIAEADKFYHENMNAFPREGWLGYKILCARTLNDNQMALNYLDSLMDYHH
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
SVGSCYPANHLLKAQFMEQMGRFEDACEVYKSYAHINDSIRSAELDEQLSKYTVQFEVDK
HCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECH
LEHDKLELRAEVNRNLFITSVIVGCLVLILLIVITFYYMRSLSLNRKLDAANKAVIKASH
HCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
MKSSFIQHITHEIRTPLNSIIGFSSLMAAGGLTQEEMEEYARQMESSNAYLLDLVNNVID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
IADMDSQTDDIPKKPVSVDACCQECLGLIRQNLKEGIKLQYMPSSTPVEVCTVEIWMKRV
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHH
LLGLLNNANKFTETGFIRLSYEEDKPNRLVRFIIEDSGPGIEEHFRDAIFERFAKADTFT
HHHHHHCCCHHCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
QGTGLGLSIIRQIMELVDGNVYLDTSYAGGARFVVEWPQ
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC
>Mature Secondary Structure
MVISLFILCFASTLAFSSTNKEKQLEALSDSVSNKIGQKDFIPFYQEYMRLARQQNDTAK
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCH
IDDAYSQIASHYYRLRNTDSLKVVAYEYMDWCLKRGNINNRYTQWRQYIQLLTEKGLQDE
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHH
AMRETGLLQKDADAAKSAFGMACSEMCIGYNHRVFSNNVKLCLEYYSSALKKFSDAGFYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCC
DAYVVSLNIIQTYLARGEYANAMEYLNRMPGLIEKMKRKDIPVRPELTMRYYQFQVIATL
CHHEEHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
ALKGKKEAQPFIAEADKFYHENMNAFPREGWLGYKILCARTLNDNQMALNYLDSLMDYHH
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHH
SVGSCYPANHLLKAQFMEQMGRFEDACEVYKSYAHINDSIRSAELDEQLSKYTVQFEVDK
HCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECH
LEHDKLELRAEVNRNLFITSVIVGCLVLILLIVITFYYMRSLSLNRKLDAANKAVIKASH
HCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
MKSSFIQHITHEIRTPLNSIIGFSSLMAAGGLTQEEMEEYARQMESSNAYLLDLVNNVID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
IADMDSQTDDIPKKPVSVDACCQECLGLIRQNLKEGIKLQYMPSSTPVEVCTVEIWMKRV
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHH
LLGLLNNANKFTETGFIRLSYEEDKPNRLVRFIIEDSGPGIEEHFRDAIFERFAKADTFT
HHHHHHCCCHHCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
QGTGLGLSIIRQIMELVDGNVYLDTSYAGGARFVVEWPQ
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7984107 [H]