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The map label for this gene is dnaX [H]

Identifier: 29347020

GI number: 29347020

Start: 1981122

End: 1982981

Strand: Reverse

Name: dnaX [H]

Synonym: BT_1610

Alternate gene names: 29347020

Gene position: 1982981-1981122 (Counterclockwise)

Preceding gene: 29347021

Following gene: 29347012

Centisome position: 31.68

GC content: 46.56

Gene sequence:

>1860_bases
ATGGAGAACTATATTGTATCAGCTCGTAAGTACCGTCCGTCCACATTCGAATCGGTGGTGGGACAACGAGCGTTGACTAC
TACATTAAAGAATGCAATCGCTACCCAGAAATTGGCTCATGCTTATTTGTTTTGCGGACCGCGCGGGGTGGGAAAGACTA
CTTGTGCGCGTATCTTCGCCAAAACCATCAACTGTATGACGCCTACTACCGATGGTGAAGCCTGCAACGAATGCGAATCG
TGTGTGGCTTTCAACGAACAGCGGTCGTATAATATCCATGAACTTGATGCCGCTTCCAACAATTCGGTGGATGATATCCG
TCAATTGGTGGAACAGGTGCGCATCCCGCCACAGATCGGTAAATATAAGGTATATATTATCGATGAGGTGCATATGCTCT
CGGCTTCCGCTTTCAACGCATTCTTGAAAACATTGGAGGAACCTCCCCGTCACGCTATCTTTATTCTGGCTACGACGGAG
AAGCATAAGATTCTTCCGACTATCCTTTCCCGTTGCCAGATTTATGATTTTAACCGGATCAGTGTCGAAGATACGGTGAA
TCATTTGTCGTACGTTGCTGCAAAAGAAAATATTACGGCAGAACCCGAAGCGCTGAATGTCATTGCGATGAAAGCGGATG
GAGGTATGCGTGACGCATTGTCTATCTTCGATCAGGTAGTGAGTTTTACGGGAGGGAATATTACTTATAAGAGTGTTATT
GAGAACTTGAACGTTCTCGATTACGAATATTATTTCCGTCTGACGGATTGTTTTCTTGAAAACAGGGTGAGTGATGCGTT
GTTGCTTTTCAATGATGTACTGAATAAAGGATTTGACGGTAGTCACTTCATCACCGGATTATCTTCGCATTGCCGGGATT
TGCTGGTCAGTAAGGATGCCGCTACCTTGCCATTACTGGAAGTAGGGGCGAGCATACGTCAGCGTTATCAGGAACAGGCG
CAGAAATGCCCGTTGCAGTTTCTTTACCGTGCGATGAAACTTTGCAATGATTGTGATTTGAATTACCGTGCCAGCAAGAA
CAAGCGCTTACTGGTGGAACTGACCTTGATACAGGTTGCCCAGCTTACCACCGAGGGGGATGACGTAAGTGGTGGGCGTG
GCCCTAAGCAGACCATAAAACCCGTATTCACCCAACCTGCCGCAGCTCAGCAGCCGCAGGTCGCTTCTGCAACGTCTGCT
CAACAGACTACTGTTCATACTGCTCCGTCTCCGGCTACTGCTCCGTCTGCCGCTAATACTGCTGTGCGTCAACCGCAGGT
ATCTGTTGCTTCGGGGGCTGCTGCTCCGGTAAATACTGCTTCCGCTCCGTCACAGAGTGCTGGAATTTCTTCGATTTCCA
AAGAGGAACGGAAGATTCCTGTGATGAAGATGTCTAGTCTGGGAGTATCTATCAAAAATCCGCAACGTGATCAGGCTGCT
CAGAATACAGCCAAAAACAATGTTGCTCAGGTTCAAATACAGCCGGAAGAAGACTTTATCTTCAACGACAGAGATTTGAA
TTATTACTGGCAGGAATATGCGGGACAGTTACCCAAAGAACAGGTAGCTATAGCAAAGCGTATGCAAGTGATACGTCCGG
TATTATTGAATAATTCGACTACTTTTGAAGTAGTGGTCGATAATGAGATTGCTGCTAAAGATTTTACAGCTTTGATTCCG
GAATTACAGACTTACCTTCGTGGAAGATTGAAGAACAGCAAAGTGGCGATGACAGTACGGGTCAGTGAACCTACGGAAAC
TGTTCGGGCGGTTGGTCGTGTTGAGAAGTTCCAGATGATGGCTCAGAAGAATCAGGCGCTCATGCAACTGAAAGATGAGT
TCGGACTTGAATTATATTAA

Upstream 100 bases:

>100_bases
AGGTTCAAAACTTCTTTCTCTATCCTTTATTACTTATCACTTTTTTGTGTACATTTGCACTGAAAGCGAAAAATCAAAAA
AAACAGAGAGAATCCCGGAT

Downstream 100 bases:

>100_bases
TGTACGGACCTCTATAAGATTTCCATCCGGATCTTTAAAGTAAATGCTCCGGATGGATATGAAAGCAATACTAATGTAAA
CGTTGATTCATTCTGCCACT

Product: DNA polymerase III subunit gamma/tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MENYIVSARKYRPSTFESVVGQRALTTTLKNAIATQKLAHAYLFCGPRGVGKTTCARIFAKTINCMTPTTDGEACNECES
CVAFNEQRSYNIHELDAASNNSVDDIRQLVEQVRIPPQIGKYKVYIIDEVHMLSASAFNAFLKTLEEPPRHAIFILATTE
KHKILPTILSRCQIYDFNRISVEDTVNHLSYVAAKENITAEPEALNVIAMKADGGMRDALSIFDQVVSFTGGNITYKSVI
ENLNVLDYEYYFRLTDCFLENRVSDALLLFNDVLNKGFDGSHFITGLSSHCRDLLVSKDAATLPLLEVGASIRQRYQEQA
QKCPLQFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQVAQLTTEGDDVSGGRGPKQTIKPVFTQPAAAQQPQVASATSA
QQTTVHTAPSPATAPSAANTAVRQPQVSVASGAAAPVNTASAPSQSAGISSISKEERKIPVMKMSSLGVSIKNPQRDQAA
QNTAKNNVAQVQIQPEEDFIFNDRDLNYYWQEYAGQLPKEQVAIAKRMQVIRPVLLNNSTTFEVVVDNEIAAKDFTALIP
ELQTYLRGRLKNSKVAMTVRVSEPTETVRAVGRVEKFQMMAQKNQALMQLKDEFGLELY

Sequences:

>Translated_619_residues
MENYIVSARKYRPSTFESVVGQRALTTTLKNAIATQKLAHAYLFCGPRGVGKTTCARIFAKTINCMTPTTDGEACNECES
CVAFNEQRSYNIHELDAASNNSVDDIRQLVEQVRIPPQIGKYKVYIIDEVHMLSASAFNAFLKTLEEPPRHAIFILATTE
KHKILPTILSRCQIYDFNRISVEDTVNHLSYVAAKENITAEPEALNVIAMKADGGMRDALSIFDQVVSFTGGNITYKSVI
ENLNVLDYEYYFRLTDCFLENRVSDALLLFNDVLNKGFDGSHFITGLSSHCRDLLVSKDAATLPLLEVGASIRQRYQEQA
QKCPLQFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQVAQLTTEGDDVSGGRGPKQTIKPVFTQPAAAQQPQVASATSA
QQTTVHTAPSPATAPSAANTAVRQPQVSVASGAAAPVNTASAPSQSAGISSISKEERKIPVMKMSSLGVSIKNPQRDQAA
QNTAKNNVAQVQIQPEEDFIFNDRDLNYYWQEYAGQLPKEQVAIAKRMQVIRPVLLNNSTTFEVVVDNEIAAKDFTALIP
ELQTYLRGRLKNSKVAMTVRVSEPTETVRAVGRVEKFQMMAQKNQALMQLKDEFGLELY
>Mature_619_residues
MENYIVSARKYRPSTFESVVGQRALTTTLKNAIATQKLAHAYLFCGPRGVGKTTCARIFAKTINCMTPTTDGEACNECES
CVAFNEQRSYNIHELDAASNNSVDDIRQLVEQVRIPPQIGKYKVYIIDEVHMLSASAFNAFLKTLEEPPRHAIFILATTE
KHKILPTILSRCQIYDFNRISVEDTVNHLSYVAAKENITAEPEALNVIAMKADGGMRDALSIFDQVVSFTGGNITYKSVI
ENLNVLDYEYYFRLTDCFLENRVSDALLLFNDVLNKGFDGSHFITGLSSHCRDLLVSKDAATLPLLEVGASIRQRYQEQA
QKCPLQFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQVAQLTTEGDDVSGGRGPKQTIKPVFTQPAAAQQPQVASATSA
QQTTVHTAPSPATAPSAANTAVRQPQVSVASGAAAPVNTASAPSQSAGISSISKEERKIPVMKMSSLGVSIKNPQRDQAA
QNTAKNNVAQVQIQPEEDFIFNDRDLNYYWQEYAGQLPKEQVAIAKRMQVIRPVLLNNSTTFEVVVDNEIAAKDFTALIP
ELQTYLRGRLKNSKVAMTVRVSEPTETVRAVGRVEKFQMMAQKNQALMQLKDEFGLELY

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=232, Percent_Identity=25.4310344827586, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI194306571, Length=232, Percent_Identity=25.4310344827586, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI194306567, Length=232, Percent_Identity=25.4310344827586, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI31563534, Length=225, Percent_Identity=25.3333333333333, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4506491, Length=247, Percent_Identity=23.8866396761134, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI31881687, Length=247, Percent_Identity=23.8866396761134, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1786676, Length=362, Percent_Identity=37.8453038674033, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1787119, Length=246, Percent_Identity=24.7967479674797, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17541988, Length=215, Percent_Identity=25.5813953488372, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324478, Length=309, Percent_Identity=23.6245954692557, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324039, Length=339, Percent_Identity=23.0088495575221, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322528, Length=218, Percent_Identity=25.2293577981651, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647857, Length=235, Percent_Identity=28.5106382978723, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18859927, Length=235, Percent_Identity=22.9787234042553, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 68578; Mature: 68578

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYIVSARKYRPSTFESVVGQRALTTTLKNAIATQKLAHAYLFCGPRGVGKTTCARIFA
CCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
KTINCMTPTTDGEACNECESCVAFNEQRSYNIHELDAASNNSVDDIRQLVEQVRIPPQIG
HHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCC
KYKVYIIDEVHMLSASAFNAFLKTLEEPPRHAIFILATTEKHKILPTILSRCQIYDFNRI
CEEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHEEECCCCC
SVEDTVNHLSYVAAKENITAEPEALNVIAMKADGGMRDALSIFDQVVSFTGGNITYKSVI
CHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEHHHHH
ENLNVLDYEYYFRLTDCFLENRVSDALLLFNDVLNKGFDGSHFITGLSSHCRDLLVSKDA
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
ATLPLLEVGASIRQRYQEQAQKCPLQFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQVA
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHH
QLTTEGDDVSGGRGPKQTIKPVFTQPAAAQQPQVASATSAQQTTVHTAPSPATAPSAANT
HHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCH
AVRQPQVSVASGAAAPVNTASAPSQSAGISSISKEERKIPVMKMSSLGVSIKNPQRDQAA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHCCCCCCCCCHHHHH
QNTAKNNVAQVQIQPEEDFIFNDRDLNYYWQEYAGQLPKEQVAIAKRMQVIRPVLLNNST
HHHHCCCEEEEEEECCCCCEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
TFEVVVDNEIAAKDFTALIPELQTYLRGRLKNSKVAMTVRVSEPTETVRAVGRVEKFQMM
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
AQKNQALMQLKDEFGLELY
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MENYIVSARKYRPSTFESVVGQRALTTTLKNAIATQKLAHAYLFCGPRGVGKTTCARIFA
CCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
KTINCMTPTTDGEACNECESCVAFNEQRSYNIHELDAASNNSVDDIRQLVEQVRIPPQIG
HHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCC
KYKVYIIDEVHMLSASAFNAFLKTLEEPPRHAIFILATTEKHKILPTILSRCQIYDFNRI
CEEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHEEECCCCC
SVEDTVNHLSYVAAKENITAEPEALNVIAMKADGGMRDALSIFDQVVSFTGGNITYKSVI
CHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEHHHHH
ENLNVLDYEYYFRLTDCFLENRVSDALLLFNDVLNKGFDGSHFITGLSSHCRDLLVSKDA
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
ATLPLLEVGASIRQRYQEQAQKCPLQFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQVA
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHH
QLTTEGDDVSGGRGPKQTIKPVFTQPAAAQQPQVASATSAQQTTVHTAPSPATAPSAANT
HHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCH
AVRQPQVSVASGAAAPVNTASAPSQSAGISSISKEERKIPVMKMSSLGVSIKNPQRDQAA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHCCCCCCCCCHHHHH
QNTAKNNVAQVQIQPEEDFIFNDRDLNYYWQEYAGQLPKEQVAIAKRMQVIRPVLLNNST
HHHHCCCEEEEEEECCCCCEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
TFEVVVDNEIAAKDFTALIPELQTYLRGRLKNSKVAMTVRVSEPTETVRAVGRVEKFQMM
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
AQKNQALMQLKDEFGLELY
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]