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The map label for this gene is corC [H]

Identifier: 29346906

GI number: 29346906

Start: 1844687

End: 1845745

Strand: Reverse

Name: corC [H]

Synonym: BT_1496

Alternate gene names: 29346906

Gene position: 1845745-1844687 (Counterclockwise)

Preceding gene: 29346907

Following gene: 29346905

Centisome position: 29.48

GC content: 42.12

Gene sequence:

>1059_bases
ATGCTCTGCAACTTCTTCTTCATGAATGTATTCGTGTTTCATTCTCCCTTGGCGGAGTTCATTATACTGACTGTAATCCT
GACTTTCCTGTTATTGTTGTTTGGAGAGATCATGCCGAAGATTTATTCAGCACAAAAGACATTGGCATTTTGCCGTTTCT
CCGCTCCGGGAATCTATTTTCTGGAGAAACTGTTTCATCCGGTTGCTTCTATGCTGGTGCGTTCTACCACTTTTCTGAAT
AAGCACTTTGCCAAGAAGAATCATAATATTTCTGTGGATGAACTTTCTCATGCATTGGAATTGACGGACAAAGCTGAAAT
TTCTGAGGAAAATAATATTTTGGAAGGAATTATCCGCTTCGGTGGTGAGACTGTGAAAGAGGTGATGACATCTCGTCTTG
ATATGGTCGATCTGGATGTCCGTACCCCTTTCAAAGAAGTGATGCAGTGTATCATTGAAAATGCTTATTCACGTATCCCT
ATTTATTCCGGTTCGCGGGATAATATCAAGGGTGTGCTATATATCAAGGACCTTCTGCCACATGTCAATAAGGGAGATAA
TTTCCGTTGGCAATCATTGATTCGCCCTGCTTATTTTGTGCCGGAGACGAAGATGATTGATGATCTGCTTCGTGATTTTC
AAGCGAATAAGATACATATTGCCATTGTGGTGGATGAGTTTGGAGGTACTTCCGGACTGGTGACAATGGAGGATATTATC
GAAGAAATCGTAGGCGAGATTCATGATGAATATGACGATGAAGAGCGCACGTATGTAGTGCTGAACGATCATACATGGAT
ATTTGAAGCAAAGACACAGTTGACTGACTTCTATAAGATTGCGAAAGTCGATGAAGATGAATTTGAAAAGGTAGTAGGTG
ACGCTGATACGCTGGCGGGCATGCTGCTCGAAATAAAAGGTGAGTTTCCGGCATTGCATGAGAAGGTGACTTATCACAAT
TATGAGTTTGAGGTGCTGGAGATGGATAGCCGCCGTATTCTGAAGGTTAAGTTCACGATTCTTCCGAAGGAGATGGATGA
GTCGGAGAGTAAGGAGTGA

Upstream 100 bases:

>100_bases
TCATCCTGCTGACGAAAAGATCAGCGCACTCCTTGGAGATTCCGAACGGCTTCTGGCTACGATACTGATCACTAACAATT
TTGTGAATGTGACCATTATC

Downstream 100 bases:

>100_bases
TGAGTAGATAAGACCTGTTCGGGCGGAGAAACTATAATCGGAGAAGAAATTATAAACCAAAAACGATGGGATTATTTCTG
CAACATAAAACGGTTGATAT

Product: hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLCNFFFMNVFVFHSPLAEFIILTVILTFLLLLFGEIMPKIYSAQKTLAFCRFSAPGIYFLEKLFHPVASMLVRSTTFLN
KHFAKKNHNISVDELSHALELTDKAEISEENNILEGIIRFGGETVKEVMTSRLDMVDLDVRTPFKEVMQCIIENAYSRIP
IYSGSRDNIKGVLYIKDLLPHVNKGDNFRWQSLIRPAYFVPETKMIDDLLRDFQANKIHIAIVVDEFGGTSGLVTMEDII
EEIVGEIHDEYDDEERTYVVLNDHTWIFEAKTQLTDFYKIAKVDEDEFEKVVGDADTLAGMLLEIKGEFPALHEKVTYHN
YEFEVLEMDSRRILKVKFTILPKEMDESESKE

Sequences:

>Translated_352_residues
MLCNFFFMNVFVFHSPLAEFIILTVILTFLLLLFGEIMPKIYSAQKTLAFCRFSAPGIYFLEKLFHPVASMLVRSTTFLN
KHFAKKNHNISVDELSHALELTDKAEISEENNILEGIIRFGGETVKEVMTSRLDMVDLDVRTPFKEVMQCIIENAYSRIP
IYSGSRDNIKGVLYIKDLLPHVNKGDNFRWQSLIRPAYFVPETKMIDDLLRDFQANKIHIAIVVDEFGGTSGLVTMEDII
EEIVGEIHDEYDDEERTYVVLNDHTWIFEAKTQLTDFYKIAKVDEDEFEKVVGDADTLAGMLLEIKGEFPALHEKVTYHN
YEFEVLEMDSRRILKVKFTILPKEMDESESKE
>Mature_352_residues
MLCNFFFMNVFVFHSPLAEFIILTVILTFLLLLFGEIMPKIYSAQKTLAFCRFSAPGIYFLEKLFHPVASMLVRSTTFLN
KHFAKKNHNISVDELSHALELTDKAEISEENNILEGIIRFGGETVKEVMTSRLDMVDLDVRTPFKEVMQCIIENAYSRIP
IYSGSRDNIKGVLYIKDLLPHVNKGDNFRWQSLIRPAYFVPETKMIDDLLRDFQANKIHIAIVVDEFGGTSGLVTMEDII
EEIVGEIHDEYDDEERTYVVLNDHTWIFEAKTQLTDFYKIAKVDEDEFEKVVGDADTLAGMLLEIKGEFPALHEKVTYHN
YEFEVLEMDSRRILKVKFTILPKEMDESESKE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=291, Percent_Identity=29.2096219931272, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI40068053, Length=284, Percent_Identity=29.2253521126761, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI40068055, Length=284, Percent_Identity=29.2253521126761, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI94681046, Length=276, Percent_Identity=28.6231884057971, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI40068049, Length=274, Percent_Identity=29.1970802919708, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786879, Length=233, Percent_Identity=35.6223175965665, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI87082033, Length=352, Percent_Identity=25.5681818181818, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI145693175, Length=340, Percent_Identity=27.3529411764706, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790664, Length=356, Percent_Identity=22.1910112359551, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788119, Length=380, Percent_Identity=22.8947368421053, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539402, Length=246, Percent_Identity=28.4552845528455, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71980512, Length=289, Percent_Identity=27.681660899654, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 40739; Mature: 40739

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCNFFFMNVFVFHSPLAEFIILTVILTFLLLLFGEIMPKIYSAQKTLAFCRFSAPGIYF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LEKLFHPVASMLVRSTTFLNKHFAKKNHNISVDELSHALELTDKAEISEENNILEGIIRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GGETVKEVMTSRLDMVDLDVRTPFKEVMQCIIENAYSRIPIYSGSRDNIKGVLYIKDLLP
CCHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCC
HVNKGDNFRWQSLIRPAYFVPETKMIDDLLRDFQANKIHIAIVVDEFGGTSGLVTMEDII
CCCCCCCCHHHHHCCCHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEHHHHH
EEIVGEIHDEYDDEERTYVVLNDHTWIFEAKTQLTDFYKIAKVDEDEFEKVVGDADTLAG
HHHHHHHHHCCCCCCCEEEEEECCEEEEECHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
MLLEIKGEFPALHEKVTYHNYEFEVLEMDSRRILKVKFTILPKEMDESESKE
HHHHCCCCCCHHHHHHEECCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MLCNFFFMNVFVFHSPLAEFIILTVILTFLLLLFGEIMPKIYSAQKTLAFCRFSAPGIYF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LEKLFHPVASMLVRSTTFLNKHFAKKNHNISVDELSHALELTDKAEISEENNILEGIIRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GGETVKEVMTSRLDMVDLDVRTPFKEVMQCIIENAYSRIPIYSGSRDNIKGVLYIKDLLP
CCHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCC
HVNKGDNFRWQSLIRPAYFVPETKMIDDLLRDFQANKIHIAIVVDEFGGTSGLVTMEDII
CCCCCCCCHHHHHCCCHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEHHHHH
EEIVGEIHDEYDDEERTYVVLNDHTWIFEAKTQLTDFYKIAKVDEDEFEKVVGDADTLAG
HHHHHHHHHCCCCCCCEEEEEECCEEEEECHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
MLLEIKGEFPALHEKVTYHNYEFEVLEMDSRRILKVKFTILPKEMDESESKE
HHHHCCCCCCHHHHHHEECCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]