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The map label for this gene is capA [H]

Identifier: 29346756

GI number: 29346756

Start: 1671731

End: 1672756

Strand: Reverse

Name: capA [H]

Synonym: BT_1346

Alternate gene names: 29346756

Gene position: 1672756-1671731 (Counterclockwise)

Preceding gene: 29346757

Following gene: 29346755

Centisome position: 26.72

GC content: 28.75

Gene sequence:

>1026_bases
ATGAAATTTGCGTATACAGGTGATTGTGTTTTACAAGACATTCAAAACATCGCTAGAACGTCGTTTGTAAATTTTGGAAA
TGAATTATCGAATAATAATTGTCGATTAATTATAAATCTAGAATCTCCATTTATCAAAGGAGATGAATCTCCTATTAAGA
ATAAAATAACTCTTTCGGCACTCCCTGATTCTATTTGTTTTCTCGATTATTTGATGCCATATTTGATAAATCTAGCAAAT
AACCATATAAATGATTATGGAAATGAGTCTGTACTTTTCACACAAGAACTATTAGATAAACACCATTTTCATTATTGGGG
AGTAGGATATAAAAATGAATTGGATAATAATGTTTGGGTTGATTCGGTTAATAAGATAATAAATATTGCTTATGTAACTC
GCACAAGCGACTTTACAGGTTCACGATTGTTTGCTGATATCGATCTAAAAGGGGGATTTTCACCTAATTTGAACCAAGTA
GAACAGATACGTAAAAAATACTGGGATTTTAGTATTATTGTTAATATTCATTGGGGAAAAGAAGATATATCATATCCTGA
ACCGGATAAAAGAGAATTAGCGCATAAGCTAATTGATGCAGGAGTAGATTTGATTATAGGACATCACCCTCATATAATTC
AACATTGTGAATACTATAAAGAAAAAATGATTTATTATTCTATTGGAAATTTTTATTTTCCTACAATTGAATATAAAATT
GATGGGAGAGTATTCTACAAAAATCCTTTAAAGCATCAAAAAATAGGACTTGTTCCTATAATTGAAATAAATCATGGTGT
TATTGATAGAATAATAACTTGGAAAGTGAAAATGGAAGATTCTGGTGAGTTGAGTTGGACTAAAAATGTAAGTCTTTCCT
ATTTACCTTCCAACATGCTATTTTATAATTTCTGTTATAAAGGGTATGAATTCATATTACTCTTAAAAAGACTATCTACT
TTCTTGAAAAGGAATTTTTCTAATCCCAAATTGGTTTTTTCTAAAATATTTGAGAAAATTGGTTGA

Upstream 100 bases:

>100_bases
ATTTATTTCGACTAAAAATAAGAAAAGTTCTTTTATTTTGGAAATATTATAGAGAAGGATGCAAAGGTGTTGTTGGTAAT
AAGAAACAATAATAAGGGAA

Downstream 100 bases:

>100_bases
ATGATAAACTAGATATAATGATGAATAATTTGAAACGGATATTAAAGAATCCAAGGCTTATTTTAATTTTTATATTATCC
CGATATTGTCATTGGATAGA

Product: capsule biosynthesis protein capA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKFAYTGDCVLQDIQNIARTSFVNFGNELSNNNCRLIINLESPFIKGDESPIKNKITLSALPDSICFLDYLMPYLINLAN
NHINDYGNESVLFTQELLDKHHFHYWGVGYKNELDNNVWVDSVNKIINIAYVTRTSDFTGSRLFADIDLKGGFSPNLNQV
EQIRKKYWDFSIIVNIHWGKEDISYPEPDKRELAHKLIDAGVDLIIGHHPHIIQHCEYYKEKMIYYSIGNFYFPTIEYKI
DGRVFYKNPLKHQKIGLVPIIEINHGVIDRIITWKVKMEDSGELSWTKNVSLSYLPSNMLFYNFCYKGYEFILLLKRLST
FLKRNFSNPKLVFSKIFEKIG

Sequences:

>Translated_341_residues
MKFAYTGDCVLQDIQNIARTSFVNFGNELSNNNCRLIINLESPFIKGDESPIKNKITLSALPDSICFLDYLMPYLINLAN
NHINDYGNESVLFTQELLDKHHFHYWGVGYKNELDNNVWVDSVNKIINIAYVTRTSDFTGSRLFADIDLKGGFSPNLNQV
EQIRKKYWDFSIIVNIHWGKEDISYPEPDKRELAHKLIDAGVDLIIGHHPHIIQHCEYYKEKMIYYSIGNFYFPTIEYKI
DGRVFYKNPLKHQKIGLVPIIEINHGVIDRIITWKVKMEDSGELSWTKNVSLSYLPSNMLFYNFCYKGYEFILLLKRLST
FLKRNFSNPKLVFSKIFEKIG
>Mature_341_residues
MKFAYTGDCVLQDIQNIARTSFVNFGNELSNNNCRLIINLESPFIKGDESPIKNKITLSALPDSICFLDYLMPYLINLAN
NHINDYGNESVLFTQELLDKHHFHYWGVGYKNELDNNVWVDSVNKIINIAYVTRTSDFTGSRLFADIDLKGGFSPNLNQV
EQIRKKYWDFSIIVNIHWGKEDISYPEPDKRELAHKLIDAGVDLIIGHHPHIIQHCEYYKEKMIYYSIGNFYFPTIEYKI
DGRVFYKNPLKHQKIGLVPIIEINHGVIDRIITWKVKMEDSGELSWTKNVSLSYLPSNMLFYNFCYKGYEFILLLKRLST
FLKRNFSNPKLVFSKIFEKIG

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 39839; Mature: 39839

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAYTGDCVLQDIQNIARTSFVNFGNELSNNNCRLIINLESPFIKGDESPIKNKITLSA
CCEEECHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEC
LPDSICFLDYLMPYLINLANNHINDYGNESVLFTQELLDKHHFHYWGVGYKNELDNNVWV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCEEECCCCCCCCCCCCCH
DSVNKIINIAYVTRTSDFTGSRLFADIDLKGGFSPNLNQVEQIRKKYWDFSIIVNIHWGK
HHHHHEEEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEEECC
EDISYPEPDKRELAHKLIDAGVDLIIGHHPHIIQHCEYYKEKMIYYSIGNFYFPTIEYKI
CCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHEEEEEECCEEEEEEEEEE
DGRVFYKNPLKHQKIGLVPIIEINHGVIDRIITWKVKMEDSGELSWTKNVSLSYLPSNML
CCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCEEEECCCEEEECCCCHH
FYNFCYKGYEFILLLKRLSTFLKRNFSNPKLVFSKIFEKIG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKFAYTGDCVLQDIQNIARTSFVNFGNELSNNNCRLIINLESPFIKGDESPIKNKITLSA
CCEEECHHHHHHHHHHHHHHHHHHCCHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEC
LPDSICFLDYLMPYLINLANNHINDYGNESVLFTQELLDKHHFHYWGVGYKNELDNNVWV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHCCCCEEECCCCCCCCCCCCCH
DSVNKIINIAYVTRTSDFTGSRLFADIDLKGGFSPNLNQVEQIRKKYWDFSIIVNIHWGK
HHHHHEEEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEEECC
EDISYPEPDKRELAHKLIDAGVDLIIGHHPHIIQHCEYYKEKMIYYSIGNFYFPTIEYKI
CCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHEEEEEECCEEEEEEEEEE
DGRVFYKNPLKHQKIGLVPIIEINHGVIDRIITWKVKMEDSGELSWTKNVSLSYLPSNML
CCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCEEEECCCEEEECCCCHH
FYNFCYKGYEFILLLKRLSTFLKRNFSNPKLVFSKIFEKIG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]