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The map label for this gene is gcp [H]

Identifier: 29346330

GI number: 29346330

Start: 1130452

End: 1131471

Strand: Reverse

Name: gcp [H]

Synonym: BT_0920

Alternate gene names: 29346330

Gene position: 1131471-1130452 (Counterclockwise)

Preceding gene: 29346332

Following gene: 29346329

Centisome position: 18.07

GC content: 44.8

Gene sequence:

>1020_bases
ATGAGTGCAATAATATTAGGAATTGAATCCTCCTGTGATGATACGTCGGCAGCCGTAATCAAGGATGGTTATCTGCTGTC
AAATGTGGTATCAAGTCAAGCCGTACATGAAGCATACGGCGGAGTAGTACCCGAATTAGCTTCACGGGCACATCAACAAA
ATATCGTTCCTGTGGTACACGAAGCACTGAAACGGGCAGGGGTTACCAAAGAAGAACTGAGCGCGGTAGCTTTCACACGT
GGACCGGGATTGATGGGATCTTTACTTGTAGGCGTCTCTTTCGCCAAAGGATTCGCACGTTCACTCGGTATTCCTTTGAT
AGATGTTAATCATCTGACAGGGCATGTCTTAGCTCATTTTATTAAAGCAGAAGGAGAAGAAAATATCCAACCGAAATTCC
CGTTCCTTTGCCTGTTGGTATCCGGAGGAAACTCACAGATTATATTGGTAAAAGCCTATAATGATATGGAAATTCTCGGT
CAGACGATTGATGACGCTGCCGGAGAAGCAATCGATAAATGTTCTAAAGTGATGGGTCTCGGATATCCGGGCGGACCGAT
CATTGACAAACTGGCACGTCAAGGCAATCCGAAAGCGTATACTTTCAGCAAACCGCATATTCCGGGGCTGGACTACAGTT
TCAGCGGACTGAAAACTTCTTTCCTATACTCCTTGCGTGACTGGATGAAAGACGATCCCGATTTCATCGAGCATCATAAA
GTGGATTTGGCCGCCTCTCTGGAAGCAACTGTTGTAGACATTCTGATGGACAAACTGCGGAAAGCTGCCAAAGAATATAA
AATAAAAGAAGTAGCCGTAGCCGGAGGAGTCTCTGCCAATAACGGATTGCGTAACTCTTTCCGAGAACACGCTGAAAAGT
ATGGCTGGAATATTTTTATTCCTAAATTCAGCTATACGACCGACAATGCAGCCATGATTGCCATTACCGGATACTTCAAG
TATCTGGATAAAGACTTCTGCTCCATTGATCTTCCGGCTTATTCCCGTGTCACATTATAA

Upstream 100 bases:

>100_bases
ATAAGCGATAACTTTTATTTAGCGAACAAAAATATAAAATAGTTCGTTATGAATCGTAGTTTTATCATTACTTTTGCACC
GTTTAATAGTTTAAAAACAT

Downstream 100 bases:

>100_bases
AACAGTTTTTTAACGTCATCGTCACTTTATATAATAAACTATTGTCATAGAATAATTTAAGTAGTGACGATTAAAGTGAC
GGCAATAACAATAGTGACGG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSAIILGIESSCDDTSAAVIKDGYLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVHEALKRAGVTKEELSAVAFTR
GPGLMGSLLVGVSFAKGFARSLGIPLIDVNHLTGHVLAHFIKAEGEENIQPKFPFLCLLVSGGNSQIILVKAYNDMEILG
QTIDDAAGEAIDKCSKVMGLGYPGGPIIDKLARQGNPKAYTFSKPHIPGLDYSFSGLKTSFLYSLRDWMKDDPDFIEHHK
VDLAASLEATVVDILMDKLRKAAKEYKIKEVAVAGGVSANNGLRNSFREHAEKYGWNIFIPKFSYTTDNAAMIAITGYFK
YLDKDFCSIDLPAYSRVTL

Sequences:

>Translated_339_residues
MSAIILGIESSCDDTSAAVIKDGYLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVHEALKRAGVTKEELSAVAFTR
GPGLMGSLLVGVSFAKGFARSLGIPLIDVNHLTGHVLAHFIKAEGEENIQPKFPFLCLLVSGGNSQIILVKAYNDMEILG
QTIDDAAGEAIDKCSKVMGLGYPGGPIIDKLARQGNPKAYTFSKPHIPGLDYSFSGLKTSFLYSLRDWMKDDPDFIEHHK
VDLAASLEATVVDILMDKLRKAAKEYKIKEVAVAGGVSANNGLRNSFREHAEKYGWNIFIPKFSYTTDNAAMIAITGYFK
YLDKDFCSIDLPAYSRVTL
>Mature_338_residues
SAIILGIESSCDDTSAAVIKDGYLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVHEALKRAGVTKEELSAVAFTRG
PGLMGSLLVGVSFAKGFARSLGIPLIDVNHLTGHVLAHFIKAEGEENIQPKFPFLCLLVSGGNSQIILVKAYNDMEILGQ
TIDDAAGEAIDKCSKVMGLGYPGGPIIDKLARQGNPKAYTFSKPHIPGLDYSFSGLKTSFLYSLRDWMKDDPDFIEHHKV
DLAASLEATVVDILMDKLRKAAKEYKIKEVAVAGGVSANNGLRNSFREHAEKYGWNIFIPKFSYTTDNAAMIAITGYFKY
LDKDFCSIDLPAYSRVTL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=339, Percent_Identity=32.7433628318584, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI8923380, Length=320, Percent_Identity=30, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1789445, Length=321, Percent_Identity=44.2367601246106, Blast_Score=270, Evalue=8e-74,
Organism=Caenorhabditis elegans, GI17557464, Length=339, Percent_Identity=29.7935103244838, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71995670, Length=326, Percent_Identity=32.2085889570552, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=345, Percent_Identity=31.304347826087, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6322891, Length=361, Percent_Identity=25.207756232687, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20129063, Length=360, Percent_Identity=33.8888888888889, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21357207, Length=325, Percent_Identity=30.4615384615385, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36775; Mature: 36643

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIILGIESSCDDTSAAVIKDGYLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVH
CCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHH
EALKRAGVTKEELSAVAFTRGPGLMGSLLVGVSFAKGFARSLGIPLIDVNHLTGHVLAHF
HHHHHCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IKAEGEENIQPKFPFLCLLVSGGNSQIILVKAYNDMEILGQTIDDAAGEAIDKCSKVMGL
HHCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
GYPGGPIIDKLARQGNPKAYTFSKPHIPGLDYSFSGLKTSFLYSLRDWMKDDPDFIEHHK
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHC
VDLAASLEATVVDILMDKLRKAAKEYKIKEVAVAGGVSANNGLRNSFREHAEKYGWNIFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCCCEEEE
PKFSYTTDNAAMIAITGYFKYLDKDFCSIDLPAYSRVTL
ECEECCCCCCEEEEEEHHHHHHCCHHCEECCCCCCCCCC
>Mature Secondary Structure 
SAIILGIESSCDDTSAAVIKDGYLLSNVVSSQAVHEAYGGVVPELASRAHQQNIVPVVH
CEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHH
EALKRAGVTKEELSAVAFTRGPGLMGSLLVGVSFAKGFARSLGIPLIDVNHLTGHVLAHF
HHHHHCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IKAEGEENIQPKFPFLCLLVSGGNSQIILVKAYNDMEILGQTIDDAAGEAIDKCSKVMGL
HHCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
GYPGGPIIDKLARQGNPKAYTFSKPHIPGLDYSFSGLKTSFLYSLRDWMKDDPDFIEHHK
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHC
VDLAASLEATVVDILMDKLRKAAKEYKIKEVAVAGGVSANNGLRNSFREHAEKYGWNIFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHCCCEEEE
PKFSYTTDNAAMIAITGYFKYLDKDFCSIDLPAYSRVTL
ECEECCCCCCEEEEEEHHHHHHCCHHCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA