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The map label for this gene is rprX [H]

Identifier: 29346143

GI number: 29346143

Start: 906714

End: 908093

Strand: Reverse

Name: rprX [H]

Synonym: BT_0733

Alternate gene names: 29346143

Gene position: 908093-906714 (Counterclockwise)

Preceding gene: 29346145

Following gene: 29346142

Centisome position: 14.51

GC content: 47.32

Gene sequence:

>1380_bases
ATGCGTACGAGCGACTTTAATGAAATCGTGCTTCGCGTCAACGAGCTGCAAAAGGATAATGTGGAACATGGTTCGGTCAC
CGTTTCCGCCGGATATGGTGCAGACGGCAAGTCGCTGGTGACAAGCCAGACCGTCTCTTATACGGACAGTACCTACAAAG
ACACCCTGCATACACGCACGGAAACAGCAGTAGATACCCTAGCCGTCAATGCCAACGATCCGGATGCCAGCGCCGTTGCC
TCCAGCGAAAGCGGACTTGATGTATTATTAAAGAAACAGGACTCGATGAAAGAACTCATACTCAGCGTCCAACAGGGTAT
GCACTCCGGCGTGGATACCTACATCGACATCAACCTGCAAAAATATGACAGTCTACTGACCGATGTACTGAAAGCACACA
ACATAGATGTGCCTCACCGTACCTTATATATATACAGCGGAGCTACTCAGGATTCATCCCAGACATTCATAGATACACTG
GGCATCGCAGGAGACAGCACCTATATCCCCAGCCCGAAAGCCATCCGCTACAACTACGAATTCAACAGGCATCACAGTCA
ACGCTACCAACTGATAATGGAACCCATCACCTCCCTGGTATGGAAACAAATGACTGGCATCCTGGTCACTTCATTTGTCA
TCTTCCTCATCCTCGGATTTTCCTTCTGGTTCCTCATCCGGACACTGCTGAAACAAAAGACGCTGGAAGAAATGAAGAGC
AACTTTACGAACAACATCACGCATGAGTTAAAGACTCCGATTGCCGTGGCGTATGCCGCCAACGATGCGCTGCTGAATTT
CAACCAGGCGGAAGAGAAAAGCAAACGTGACCAATATCTGCGCATCAGCCAAGAGCAGCTACAGCGTTTGAGCGGACTCG
TCGAACAGATTCTTTCCATGAGCATGGAAAGCCGCAAGACGTTCAGACTGCACCCCGAAGAGATTTGTCTAAAAGAACTG
ATTACTTCTTTAATAGAGCAGCACCAGCTAAAAGCGGATATCCCCGTACACATAACACTGGAAACAGAACCGGAAGCACT
GACGATAGTAGCCGACCGCACTCATTTCAGCAATATCATCAGTAACCTGATAGACAATGCCGTGAAATATTCGAAACAAG
AAGCAGAGATTATGATTCAGTGCCGCCAAACGGGAGAAACGGTGACTATCACCGTCTCTGATCATGGAATAGGTATCCCT
CTGGATAAACAGAAACATATATTCGACAAATTCTATCGCGTTCCGACCGGAAATCTTCATAACGTGAAGGGATACGGCTT
AGGGCTTTTCTATGTCAAAAGCATGGTCGAAAAACATGGAGGCACCATCACCGTCAAAAGTGAATCCGGCAAAGGAAGTA
CATTTACCATTACTATCTAA

Upstream 100 bases:

>100_bases
CATCTGCTCGCTGACAGGCATCTTTGTTTACCAGACATATTGGCTGACAGGGCTTTACCGCACGATGAAGCAGGAAATGA
ACAATAATATCAAAGACGCC

Downstream 100 bases:

>100_bases
AACATCAGAACCATGAGCAAAAACGACATTACAGTATTGTTGGTGGAAGACGAACTGACACTCGCCATGATTATCAAAGA
TACGCTCGAGGAAAACGGTT

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRTSDFNEIVLRVNELQKDNVEHGSVTVSAGYGADGKSLVTSQTVSYTDSTYKDTLHTRTETAVDTLAVNANDPDASAVA
SSESGLDVLLKKQDSMKELILSVQQGMHSGVDTYIDINLQKYDSLLTDVLKAHNIDVPHRTLYIYSGATQDSSQTFIDTL
GIAGDSTYIPSPKAIRYNYEFNRHHSQRYQLIMEPITSLVWKQMTGILVTSFVIFLILGFSFWFLIRTLLKQKTLEEMKS
NFTNNITHELKTPIAVAYAANDALLNFNQAEEKSKRDQYLRISQEQLQRLSGLVEQILSMSMESRKTFRLHPEEICLKEL
ITSLIEQHQLKADIPVHITLETEPEALTIVADRTHFSNIISNLIDNAVKYSKQEAEIMIQCRQTGETVTITVSDHGIGIP
LDKQKHIFDKFYRVPTGNLHNVKGYGLGLFYVKSMVEKHGGTITVKSESGKGSTFTITI

Sequences:

>Translated_459_residues
MRTSDFNEIVLRVNELQKDNVEHGSVTVSAGYGADGKSLVTSQTVSYTDSTYKDTLHTRTETAVDTLAVNANDPDASAVA
SSESGLDVLLKKQDSMKELILSVQQGMHSGVDTYIDINLQKYDSLLTDVLKAHNIDVPHRTLYIYSGATQDSSQTFIDTL
GIAGDSTYIPSPKAIRYNYEFNRHHSQRYQLIMEPITSLVWKQMTGILVTSFVIFLILGFSFWFLIRTLLKQKTLEEMKS
NFTNNITHELKTPIAVAYAANDALLNFNQAEEKSKRDQYLRISQEQLQRLSGLVEQILSMSMESRKTFRLHPEEICLKEL
ITSLIEQHQLKADIPVHITLETEPEALTIVADRTHFSNIISNLIDNAVKYSKQEAEIMIQCRQTGETVTITVSDHGIGIP
LDKQKHIFDKFYRVPTGNLHNVKGYGLGLFYVKSMVEKHGGTITVKSESGKGSTFTITI
>Mature_459_residues
MRTSDFNEIVLRVNELQKDNVEHGSVTVSAGYGADGKSLVTSQTVSYTDSTYKDTLHTRTETAVDTLAVNANDPDASAVA
SSESGLDVLLKKQDSMKELILSVQQGMHSGVDTYIDINLQKYDSLLTDVLKAHNIDVPHRTLYIYSGATQDSSQTFIDTL
GIAGDSTYIPSPKAIRYNYEFNRHHSQRYQLIMEPITSLVWKQMTGILVTSFVIFLILGFSFWFLIRTLLKQKTLEEMKS
NFTNNITHELKTPIAVAYAANDALLNFNQAEEKSKRDQYLRISQEQLQRLSGLVEQILSMSMESRKTFRLHPEEICLKEL
ITSLIEQHQLKADIPVHITLETEPEALTIVADRTHFSNIISNLIDNAVKYSKQEAEIMIQCRQTGETVTITVSDHGIGIP
LDKQKHIFDKFYRVPTGNLHNVKGYGLGLFYVKSMVEKHGGTITVKSESGKGSTFTITI

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=30.9734513274336, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI48994928, Length=227, Percent_Identity=31.7180616740088, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=28.6324786324786, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=29.2035398230088, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787374, Length=217, Percent_Identity=32.7188940092166, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=25.5506607929515, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=25.8771929824561, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790346, Length=246, Percent_Identity=26.0162601626016, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=24.8888888888889, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=24.6696035242291, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=26.2931034482759, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=27.9279279279279, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790861, Length=204, Percent_Identity=28.4313725490196, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788279, Length=209, Percent_Identity=27.7511961722488, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=218, Percent_Identity=25.6880733944954, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51581; Mature: 51581

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSDFNEIVLRVNELQKDNVEHGSVTVSAGYGADGKSLVTSQTVSYTDSTYKDTLHTRT
CCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHEECEEECCCCHHHHHHHHHH
ETAVDTLAVNANDPDASAVASSESGLDVLLKKQDSMKELILSVQQGMHSGVDTYIDINLQ
HHHHHEEEEECCCCCHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEHH
KYDSLLTDVLKAHNIDVPHRTLYIYSGATQDSSQTFIDTLGIAGDSTYIPSPKAIRYNYE
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEE
FNRHHSQRYQLIMEPITSLVWKQMTGILVTSFVIFLILGFSFWFLIRTLLKQKTLEEMKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFTNNITHELKTPIAVAYAANDALLNFNQAEEKSKRDQYLRISQEQLQRLSGLVEQILSM
HHCCCCHHHHCCCEEEEEECCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SMESRKTFRLHPEEICLKELITSLIEQHQLKADIPVHITLETEPEALTIVADRTHFSNII
HHHCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCHHHHHHH
SNLIDNAVKYSKQEAEIMIQCRQTGETVTITVSDHGIGIPLDKQKHIFDKFYRVPTGNLH
HHHHHHHHHHCCHHHHEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCC
NVKGYGLGLFYVKSMVEKHGGTITVKSESGKGSTFTITI
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEC
>Mature Secondary Structure
MRTSDFNEIVLRVNELQKDNVEHGSVTVSAGYGADGKSLVTSQTVSYTDSTYKDTLHTRT
CCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHEECEEECCCCHHHHHHHHHH
ETAVDTLAVNANDPDASAVASSESGLDVLLKKQDSMKELILSVQQGMHSGVDTYIDINLQ
HHHHHEEEEECCCCCHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEHH
KYDSLLTDVLKAHNIDVPHRTLYIYSGATQDSSQTFIDTLGIAGDSTYIPSPKAIRYNYE
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEE
FNRHHSQRYQLIMEPITSLVWKQMTGILVTSFVIFLILGFSFWFLIRTLLKQKTLEEMKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFTNNITHELKTPIAVAYAANDALLNFNQAEEKSKRDQYLRISQEQLQRLSGLVEQILSM
HHCCCCHHHHCCCEEEEEECCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SMESRKTFRLHPEEICLKELITSLIEQHQLKADIPVHITLETEPEALTIVADRTHFSNII
HHHCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCHHHHHHH
SNLIDNAVKYSKQEAEIMIQCRQTGETVTITVSDHGIGIPLDKQKHIFDKFYRVPTGNLH
HHHHHHHHHHCCHHHHEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCC
NVKGYGLGLFYVKSMVEKHGGTITVKSESGKGSTFTITI
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]